| # | Title | Journal | Year | Citations |
|---|
| 1 | Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 9,122 |
| 2 | Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria | Lancet Neurology, The | 2018 | 4,605 |
| 3 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 4 | Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease | Nature Genetics | 2009 | 2,155 |
| 5 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 6 | Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: A multiple-center epidemiological study* | Critical Care Medicine | 2005 | 1,885 |
| 7 | An anomalous positron abundance in cosmic rays with energies 1.5–100 GeV | Nature | 2009 | 1,794 |
| 8 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 9 | Systematic Pelvic Lymphadenectomy vs No Lymphadenectomy in Early-Stage Endometrial Carcinoma: Randomized Clinical Trial | Journal of the National Cancer Institute | 2008 | 1,316 |
| 10 | Modulation of anxiety through blockade of anandamide hydrolysis | Nature Medicine | 2003 | 1,306 |
| 11 | Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia | New England Journal of Medicine | 2013 | 1,284 |
| 12 | Evolutionary and Biomedical Insights from the Rhesus Macaque Genome | Science | 2007 | 1,283 |
| 13 | Utilisation of CO2 as a chemical feedstock: opportunities and challenges | Dalton Transactions | 2007 | 1,260 |
| 14 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study | Intensive Care Medicine | 2004 | 1,188 |
| 15 | High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome | Gut | 2016 | 1,092 |
| 16 | The Metabolic Signature of Macrophage Responses | Frontiers in Immunology | 2019 | 1,083 |
| 17 | Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita | Nature Biotechnology | 2008 | 1,012 |
| 18 | Efficacy of Implantable Cardioverter–Defibrillators for the Prevention of Sudden Death in Patients with Hypertrophic Cardiomyopathy | New England Journal of Medicine | 2000 | 953 |
| 19 | Sirolimus for Kaposi's Sarcoma in Renal-Transplant Recipients | New England Journal of Medicine | 2005 | 924 |
| 20 | The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update | Allergy: European Journal of Allergy and Clinical Immunology | 2014 | 912 |
| 21 | Amyotrophic lateral sclerosis | Nature Reviews Disease Primers | 2017 | 885 |
| 22 | Standards for epidemiologic studies and surveillance of epilepsy | Epilepsia | 2011 | 836 |
| 23 | Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG) | Archives of Virology | 2011 | 827 |
| 24 | Nitrate in vegetables: toxicity, content, intake and EC regulation | Journal of the Science of Food and Agriculture | 2006 | 807 |
| 25 | Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases | Vascular Pharmacology | 2018 | 805 |
| 26 | Ticks and tick-borne diseases: a One Health perspective | Trends in Parasitology | 2012 | 802 |
| 27 | Electroluminescent materials for white organic light emitting diodes | Chemical Society Reviews | 2011 | 794 |
| 28 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 29 | The Controversial Role of Human Gut Lachnospiraceae | Microorganisms | 2020 | 777 |
| 30 | The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis | Nature Reviews Cancer | 2005 | 775 |
| 31 | Great ape genetic diversity and population history | Nature | 2013 | 768 |
| 32 | Genome-Wide Analysis of the World's Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection | PLoS Biology | 2012 | 719 |
| 33 | Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection | Lancet, The | 1995 | 692 |
| 34 | Genome Sequence, Comparative Analysis, and Population Genetics of the Domestic Horse | Science | 2009 | 680 |
| 35 | A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease | Nature Reviews Neurology | 2019 | 666 |
| 36 | Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature | Neuroepidemiology | 2013 | 659 |
| 37 | The mitochondrial transporter family (SLC25): physiological and pathological implications | Pflugers Archiv European Journal of Physiology | 2004 | 655 |
| 38 | Incidence of amyotrophic lateral sclerosis in Europe | Journal of Neurology, Neurosurgery and Psychiatry | 2010 | 648 |
| 39 | Complementary Feeding | Journal of Pediatric Gastroenterology and Nutrition | 2017 | 644 |
| 40 | Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments | Archives of Virology | 2008 | 642 |
| 41 | Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricular asynchrony | Journal of the American College of Cardiology | 2002 | 641 |
| 42 | Fecal Microbiota and Metabolome of Children with Autism and Pervasive Developmental Disorder Not Otherwise Specified | PLoS ONE | 2013 | 640 |
| 43 | Building knowledge through families of experiments | IEEE Transactions on Software Engineering | 1999 | 632 |
| 44 | Identification of Enteramine, the Specific Hormone of the Enterochromaffin Cell System, as 5-Hydroxytryptamine | Nature | 1952 | 614 |
| 45 | Influence of processing on the antioxidant properties of fruit and vegetables | Trends in Food Science and Technology | 1999 | 613 |
| 46 | FSH Directly Regulates Bone Mass | Cell | 2006 | 612 |
| 47 | Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 609 |
| 48 | Inhomogeneous superconductivity in condensed matter and QCD | Reviews of Modern Physics | 2004 | 586 |
| 49 | Sustained virological response to interferon-α is associated with improved outcome in HCV-related cirrhosis: A retrospective study | Hepatology | 2007 | 585 |
| 50 | Knowledge Graphs | ACM Computing Surveys | 2022 | 585 |
