| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | JNdi-1: a neodymium isotopic reference in consistency with LaJolla neodymium | Chemical Geology | 2000 | 1,418 |
| 3 | Coral bleaching: the winners and the losers | Ecology Letters | 2001 | 1,297 |
| 4 | Systematic Revision of Symbiodiniaceae Highlights the Antiquity and Diversity of Coral Endosymbionts | Current Biology | 2018 | 1,242 |
| 5 | The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019) | Hypertension Research | 2019 | 1,047 |
| 6 | Typing Hepatitis B Virus by Homology in Nucleotide Sequence: Comparison of Surface Antigen Subtypes | Journal of General Virology | 1988 | 972 |
| 7 | The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014) | Hypertension Research | 2014 | 962 |
| 8 | Origin of Mesozoic adakitic intrusive rocks in the Ningzhen area of east China: Partial melting of delaminated lower continental crust? | Geology | 2002 | 817 |
| 9 | Plant phenolic antioxidant and prooxidant activities: phenolics-induced oxidative damage mediated by metals in plants | Toxicology | 2002 | 702 |
| 10 | Cell proliferation at 122°C and isotopically heavy CH 4 production by a hyperthermophilic methanogen under high-pressure cultivation | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 679 |
| 11 | Free-radical scavenging action of medicinal herbs from Ghana | General Pharmacology | 1999 | 641 |
| 12 | Spread of HTLV-I Between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton | Science | 2003 | 640 |
| 13 | The projected timing of climate departure from recent variability | Nature | 2013 | 579 |
| 14 | Body mass index and the risk of development of end-stage renal disease in a screened cohort | Kidney International | 2004 | 490 |
| 15 | Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease | Clinical and Experimental Nephrology | 2007 | 488 |
| 16 | Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages | PLoS Pathogens | 2007 | 469 |
| 17 | IL-17-Mediated Regulation of Innate and Acquired Immune Response against Pulmonary Mycobacterium bovis Bacille Calmette-Guérin Infection | Journal of Immunology | 2007 | 466 |
| 18 | Cellulolytic Systems in Insects | Annual Review of Entomology | 2010 | 464 |
| 19 | Simultaneous production of nitric oxide and peroxynitrite by plant nitrate reductase: in vitro evidence for the NR-dependent formation of active nitrogen species | FEBS Letters | 2000 | 462 |
| 20 | Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals | Journal of Immunology | 2002 | 460 |
| 21 | Apology as aggression control: Its role in mediating appraisal of and response to harm. | Journal of Personality and Social Psychology | 1989 | 457 |
| 22 | Pachychoroid disease | Eye | 2019 | 443 |
| 23 | Neural-network-based maximum-power-point tracking of coupled-inductor interleaved-boost-converter-supplied pv system using fuzzy controller | IEEE Transactions on Industrial Electronics | 2003 | 430 |
| 24 | CT-guided needle biopsy of lung lesions: A survey of severe complication based on 9783 biopsies in Japan | European Journal of Radiology | 2006 | 404 |
| 25 | Output Power Leveling of Wind Turbine Generator for All Operating Regions by Pitch Angle Control | IEEE Transactions on Energy Conversion | 2006 | 402 |
| 26 | Flavonoid-Peroxidase Reaction as a Detoxification Mechanism of Plant Cells against H2O2 | Plant Physiology | 1997 | 388 |
| 27 | Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan | Hepatology | 2001 | 387 |
| 28 | A Genetic Variant of Hepatitis B Virus Divergent from Known Human and Ape Genotypes Isolated from a Japanese Patient and Provisionally Assigned to New Genotype J | Journal of Virology | 2009 | 367 |
| 29 | Age Related Changes in 5‐methylcytosine Content in Human Peripheral Leukocytes and Placentas: an HPLC‐based Study | Annals of Human Genetics | 2004 | 362 |
| 30 | A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C | Hepatology | 2001 | 361 |
| 31 | Sexual Dimorphic Expression of Genes in Gonads During Early Differentiation of a Teleost Fish, the Nile Tilapia Oreochromis niloticus1 | Biology of Reproduction | 2008 | 354 |
| 32 | Optimal Distribution Voltage Control and Coordination With Distributed Generation | IEEE Transactions on Power Delivery | 2008 | 354 |
| 33 | Mechanical properties of biodegradable composites reinforced with bagasse fibre before and after alkali treatments | Composites Part A: Applied Science and Manufacturing | 2006 | 349 |
| 34 | Hypoadiponectinemia Is Closely Linked to Endothelial Dysfunction in Man | Journal of Clinical Endocrinology and Metabolism | 2003 | 345 |
| 35 | Geochemical variation within the northern Ryukyu Arc: magma source compositions and geodynamic implications | Contributions To Mineralogy and Petrology | 2000 | 343 |
| 36 | A fast technique for unit commitment problem by extended priority list | IEEE Transactions on Power Systems | 2003 | 342 |
| 37 | Inclusive fitness theory and eusociality | Nature | 2011 | 339 |
| 38 | An alternative pathway for nitric oxide production in plants: new features of an old enzyme | Trends in Plant Science | 1999 | 338 |
| 39 | Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung | Journal of Immunology | 2010 | 338 |
| 40 | Significance of Hyperuricemia on the Early Detection of Renal Failure in a Cohort of Screened Subjects. | Hypertension Research | 2001 | 335 |
| 41 | A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303 | British Journal of Haematology | 2001 | 335 |
| 42 | Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly | Hypertension | 2010 | 334 |
| 43 | A Hybrid Power System Using Alternative Energy Facilities in Isolated Island | IEEE Transactions on Energy Conversion | 2005 | 329 |
| 44 | Bcl11b is required for differentiation and survival of αβ T lymphocytes | Nature Immunology | 2003 | 317 |
| 45 | Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A | Nature Chemical Biology | 2006 | 317 |
| 46 | Diagnostic Criteria, Clinical Features, and Incidence of Thyroid Storm Based on Nationwide Surveys | Thyroid | 2012 | 315 |
| 47 | IL-17A Produced by γδ T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver | Journal of Immunology | 2008 | 312 |
| 48 | Closely related Symbiodinium spp. differ in relative dominance in coral reef host communities across environmental, latitudinal and biogeographic gradients | Marine Ecology - Progress Series | 2004 | 312 |
| 49 | Geographic patterns of endemism and speciation in amphibians and reptiles of the Ryukyu Archipelago, Japan, with special reference to their paleogeographical implications | Researches on Population Ecology | 1998 | 311 |
| 50 | Hypocholesterolemia is a significant predictor of death in a cohort of chronic hemodialysis patients | Kidney International | 2002 | 308 |
