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Top Articles

#TitleJournalYearCitations
1International uniform response criteria for multiple myelomaLeukemia20062,332
2Identifying ChIP-seq enrichment using MACSNature Protocols20121,471
3The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and ImmunogensScience19981,421
4Apoptosis in cancer therapy: Crossing the thresholdCell19941,291
5The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor SignalingScience2011973
6Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinomaScience2018898
7A new classification for HIV-1Nature1998733
8Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01Blood2001728
9International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disordersLeukemia2009686
10microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.Genes and Development1994593
11Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group reportBlood2015586
12Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutationHuman Molecular Genetics1998578
13The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory CommitteeBlood2022512
14p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BADProceedings of the National Academy of Sciences of the United States of America2001487
15Human γδ+ T cells respond to mycobacterial heat-shock proteinNature1989459
16A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cellsLeukemia Research1984391
17Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remissionBlood2005361
18Institutional implementation of clinical tumor profiling on an unselected cancer populationJCI Insight2016340
19The Murine CAR Homolog Is a Receptor for Coxsackie B Viruses and AdenovirusesJournal of Virology1998330
20Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells*Journal of Biological Chemistry2014309
21Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patientsNature2010302
22Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomouslyNature Microbiology2016301
23Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trialsLancet, The2020266
24Crystal Structure of the I Domain from Integrin α2β1Journal of Biological Chemistry1997264
25Coxsackievirus B3 adapted to growth in RD cells binds to decay-accelerating factor (CD55)Journal of Virology1995264
26Comparing Patient-Reported Hospital Adverse Events with Medical Record Review: Do Patients Know Something That Hospitals Do Not?Annals of Internal Medicine2008263
27The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus.Proceedings of the National Academy of Sciences of the United States of America1988258
28Spatially organized multicellular immune hubs in human colorectal cancerCell2021256
29Survival Factor-Mediated BAD Phosphorylation Raises the Mitochondrial Threshold for ApoptosisDevelopmental Cell2002255
30Molecular Study of Malignant Gliomas Treated with Epidermal Growth Factor Receptor Inhibitors: Tissue Analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01Clinical Cancer Research2005238
31Bony Morbidity in Children Treated for Acute Lymphoblastic LeukemiaJournal of Clinical Oncology2001227
32Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathwayNature Medicine2010224
33Tacrolimus and pimecrolimus: From clever prokaryotes to inhibiting calcineurin and treating atopic dermatitisJournal of the American Academy of Dermatology2002221
34Global MicroRNA Expression Profiling Identifies MiR-210 Associated with Tumor Proliferation, Invasion and Poor Clinical Outcome in Breast CancerPLoS ONE2011214
35Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MMBlood2016207
36Pembrolizumab as first-line therapy for patients with PD-L1-positive advanced non-small cell lung cancer: a phase 1 trialAnnals of Oncology2017197
37The von Hippel-Lindau Tumor Suppressor Gene Inhibits Hepatocyte Growth Factor/Scatter Factor-Induced Invasion and Branching Morphogenesis in Renal Carcinoma CellsMolecular and Cellular Biology1999194
38Cost Effectiveness of Prophylactic Intravenous Immune Globulin in Chronic Lymphocytic LeukemiaNew England Journal of Medicine1991187
39Simple ODE models of tumor growth and anti-angiogenic or radiation treatmentMathematical and Computer Modelling2001187
40Extracellular antigen processing and presentation by immature dendritic cellsProceedings of the National Academy of Sciences of the United States of America1999182
41Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cellsLeukemia2013166
42Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencingBMC Genomics2018157
43Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27kip1Blood2001155
44Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesisNature2017155
45Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance ImagingJAMA Oncology2017148
46Formats for Improving Risk Communication in Medical Tradeoff DecisionsJournal of Health Communication2006144
47Children's Oncology Group's 2013 blueprint for research: Renal tumorsPediatric Blood and Cancer2013140
48How oxygen makes its presence feltGenes and Development2002138
49Value of follow-up procedures in patients with large-cell lymphoma who achieve a complete remission.Journal of Clinical Oncology1991137
50Linking the SWI/SNF complex to prostate cancerNature Genetics2013137