| # | Title | Journal | Year | Citations |
|---|
| 1 | Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor | Science | 2000 | 5,486 |
| 2 | Life with 6000 Genes | Science | 1996 | 3,548 |
| 3 | Anomalous Hall effect | Reviews of Modern Physics | 2010 | 3,276 |
| 4 | 4 Lipid and Cell-Wall Analysis in Bacterial Systematics | Methods in Microbiology | 1988 | 2,621 |
| 5 | Classification of topological insulators and superconductors in three spatial dimensions | Physical Review B | 2008 | 2,608 |
| 6 | A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications | Nature Biotechnology | 2002 | 2,518 |
| 7 | Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis | Nature Cell Biology | 2000 | 2,487 |
| 8 | MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity | Journal of Clinical Investigation | 2006 | 2,190 |
| 9 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 10 | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations | Nature Genetics | 2015 | 1,965 |
| 11 | Parity–time-symmetric whispering-gallery microcavities | Nature Physics | 2014 | 1,892 |
| 12 | Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression | Cell | 2008 | 1,888 |
| 13 | Quantum simulation | Reviews of Modern Physics | 2014 | 1,881 |
| 14 | ABSCISIC ACID BIOSYNTHESIS AND CATABOLISM | Annual Review of Plant Biology | 2005 | 1,871 |
| 15 | Observation of the spin Seebeck effect | Nature | 2008 | 1,858 |
| 16 | A ROCK inhibitor permits survival of dissociated human embryonic stem cells | Nature Biotechnology | 2007 | 1,849 |
| 17 | Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome | Nature | 2013 | 1,774 |
| 18 | α-Synuclein is phosphorylated in synucleinopathy lesions | Nature Cell Biology | 2002 | 1,739 |
| 19 | A more efficient method to generate integration-free human iPS cells | Nature Methods | 2011 | 1,736 |
| 20 | Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA | Cell | 2014 | 1,690 |
| 21 | THENUCLEAR SPECTROSCOPIC TELESCOPE ARRAY(NuSTAR) HIGH-ENERGY X-RAY MISSION | Astrophysical Journal | 2013 | 1,627 |
| 22 | Cytokinin Oxidase Regulates Rice Grain Production | Science | 2005 | 1,620 |
| 23 | Stretchable active-matrix organic light-emitting diode display using printable elastic conductors | Nature Materials | 2009 | 1,620 |
| 24 | Topological insulators and superconductors: tenfold way and dimensional hierarchy | New Journal of Physics | 2010 | 1,588 |
| 25 | LaFeAsO1−xFx">Unconventional Pairing Originating from the Disconnected Fermi Surfaces of SuperconductingLaFeAsO1−xFx | Physical Review Letters | 2008 | 1,532 |
| 26 | Spin–orbit interactions of light | Nature Photonics | 2015 | 1,526 |
| 27 | Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways | Nature Neuroscience | 2002 | 1,485 |
| 28 | Genomics and Evolution of Heritable Bacterial Symbionts | Annual Review of Genetics | 2008 | 1,460 |
| 29 | MgxZn1−xO as a II–VI widegap semiconductor alloy | Applied Physics Letters | 1998 | 1,447 |
| 30 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 31 | QuTiP 2: A Python framework for the dynamics of open quantum systems | Computer Physics Communications | 2013 | 1,384 |
| 32 | Erasers of Histone Acetylation: The Histone Deacetylase Enzymes | Cold Spring Harbor Perspectives in Biology | 2014 | 1,346 |
| 33 | Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting | Nature | 2004 | 1,242 |
| 34 | CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 1,225 |
| 35 | Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease | Nature Genetics | 2009 | 1,217 |
| 36 | Genome-wide analysis of mammalian promoter architecture and evolution | Nature Genetics | 2006 | 1,201 |
| 37 | Humanized mice in translational biomedical research | Nature Reviews Immunology | 2007 | 1,189 |
| 38 | The DNA sequence of human chromosome 21 | Nature | 2000 | 1,144 |
| 39 | QuTiP: An open-source Python framework for the dynamics of open quantum systems | Computer Physics Communications | 2012 | 1,143 |
| 40 | Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,129 |
| 41 | Highly inclined thin illumination enables clear single-molecule imaging in cells | Nature Methods | 2008 | 1,109 |
| 42 | Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain | Nature Neuroscience | 2011 | 1,096 |
| 43 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME | Archives of Toxicology | 2013 | 1,089 |
| 44 | Atomic physics and quantum optics using superconducting circuits | Nature | 2011 | 1,053 |
| 45 | Cohesin mediates transcriptional insulation by CCCTC-binding factor | Nature | 2008 | 1,050 |
| 46 | Native structure of photosystem II at 1.95 Å resolution viewed by femtosecond X-ray pulses | Nature | 2015 | 1,050 |
| 47 | The medaka draft genome and insights into vertebrate genome evolution | Nature | 2007 | 1,037 |
| 48 | The Arabidopsis GNOM ARF-GEF Mediates Endosomal Recycling, Auxin Transport, and Auxin-Dependent Plant Growth | Cell | 2003 | 1,027 |
| 49 | Research on plant abiotic stress responses in the post‐genome era: past, present and future | Plant Journal | 2010 | 1,021 |
| 50 | Phase-Sensitive Observation of a Spin-Orbital Mott State in Sr 2 IrO 4 | Science | 2009 | 1,008 |
