| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Roles of CHOP/GADD153 in endoplasmic reticulum stress | Cell Death and Differentiation | 2004 | 2,440 |
| 3 | Cyclodextrin Drug Carrier Systems | Chemical Reviews | 1998 | 1,977 |
| 4 | Structural Basis of the Drug-binding Specificity of Human Serum Albumin | Journal of Molecular Biology | 2005 | 1,617 |
| 5 | JNdi-1: a neodymium isotopic reference in consistency with LaJolla neodymium | Chemical Geology | 2000 | 1,418 |
| 6 | Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure. | Circulation | 1994 | 1,262 |
| 7 | ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim | Cell | 2007 | 1,235 |
| 8 | Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus | Journal of Diabetes Investigation | 2010 | 1,206 |
| 9 | Guidelines and definitions for research on epithelial–mesenchymal transition | Nature Reviews Molecular Cell Biology | 2020 | 1,195 |
| 10 | Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells | Nature | 2004 | 1,084 |
| 11 | Cohesin mediates transcriptional insulation by CCCTC-binding factor | Nature | 2008 | 1,050 |
| 12 | The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019) | Hypertension Research | 2019 | 1,047 |
| 13 | CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth | Cancer Cell | 2011 | 1,020 |
| 14 | Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D | Nature | 2004 | 1,016 |
| 15 | Rapidly Solidified Powder Metallurgy Mg97Zn1Y2Alloys with Excellent Tensile Yield Strength above 600 MPa | Materials Transactions | 2001 | 993 |
| 16 | Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome | Cell | 2017 | 973 |
| 17 | Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 924 |
| 18 | CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy | Cancer Treatment Reviews | 2018 | 867 |
| 19 | AAA+superfamily ATPases: common structure-diverse function | Genes To Cells | 2001 | 864 |
| 20 | α-Catenin as a tension transducer that induces adherens junction development | Nature Cell Biology | 2010 | 864 |
| 21 | Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1 | Nature | 2010 | 859 |
| 22 | Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis | Journal of Biological Chemistry | 2003 | 783 |
| 23 | Pharmaceutical Applications of Cyclodextrins. III. Toxicological Issues and Safety Evaluation | Journal of Pharmaceutical Sciences | 1997 | 779 |
| 24 | A Tetranuclear 3d−4f Single Molecule Magnet: [CuIILTbIII(hfac)2]2 | Journal of the American Chemical Society | 2004 | 773 |
| 25 | Practical Aspects of the Ligand-Binding and Enzymatic Properties of Human Serum Albumin. | Biological and Pharmaceutical Bulletin | 2002 | 764 |
| 26 | Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity | Nature | 2022 | 756 |
| 27 | International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values | Journal of Diabetes Investigation | 2012 | 731 |
| 28 | Crack classification in concrete based on acoustic emission | Construction and Building Materials | 2010 | 730 |
| 29 | Mutational landscape and clonal architecture in grade II and III gliomas | Nature Genetics | 2015 | 729 |
| 30 | Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells | Cell Stem Cell | 2014 | 725 |
| 31 | Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations | Nature Medicine | 2014 | 723 |
| 32 | Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis | Gut | 2016 | 718 |
| 33 | Low-Dose Aspirin for Primary Prevention of Atherosclerotic Events in Patients With Type 2 Diabetes<subtitle>A Randomized Controlled Trial</subtitle> | JAMA - Journal of the American Medical Association | 2008 | 710 |
| 34 | Hippo pathway regulation by cell morphology and stress fibers | Development (Cambridge) | 2011 | 707 |
| 35 | Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake | Cell Metabolism | 2007 | 701 |
| 36 | Epithelial–mesenchymal transition in cancer development and its clinical significance | Cancer Science | 2010 | 691 |
| 37 | Possible involvement of the M2 anti‐inflammatory macrophage phenotype in growth of human gliomas | Journal of Pathology | 2008 | 663 |
| 38 | Aurora-A — A guardian of poles | Nature Reviews Cancer | 2005 | 655 |
| 39 | The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway | Genes To Cells | 2003 | 651 |
| 40 | Long-period ordered structure in a high-strength nanocrystalline Mg-1 at% Zn-2 at% Y alloy studied by atomic-resolution Z-contrast STEM | Acta Materialia | 2002 | 650 |
| 41 | Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis | Nature Genetics | 1996 | 588 |
| 42 | Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure. | Circulation | 1993 | 584 |
| 43 | DNA Methylation Is a Critical Cell-Intrinsic Determinant of Astrocyte Differentiation in the Fetal Brain | Developmental Cell | 2001 | 570 |
| 44 | Aurora-A and an Interacting Activator, the LIM Protein Ajuba, Are Required for Mitotic Commitment in Human Cells | Cell | 2003 | 563 |
| 45 | Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA | Nature Chemical Biology | 2007 | 563 |
| 46 | Repurposing Diflunisal for Familial Amyloid Polyneuropathy | JAMA - Journal of the American Medical Association | 2013 | 551 |
| 47 | Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody | Nature | 1992 | 547 |
| 48 | Bisphenol S in Urine from the United States and Seven Asian Countries: Occurrence and Human Exposures | Environmental Science & Technology | 2012 | 546 |
| 49 | Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes | FEBS Journal | 1989 | 545 |
| 50 | Effect of long-period stacking ordered phase on mechanical properties of Mg97Zn1Y2 extruded alloy | Acta Materialia | 2010 | 543 |
