| # | Title | Journal | Year | Citations |
|---|
| 1 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1) | European Journal of Cancer | 2009 | 21,739 |
| 2 | The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 12,681 |
| 3 | 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2016 | 10,674 |
| 4 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells | Nature Cell Biology | 2007 | 10,558 |
| 5 | The 2007 WHO Classification of Tumours of the Central Nervous System | Acta Neuropathologica | 2007 | 9,898 |
| 6 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 7 | Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria | Annals of Neurology | 2011 | 8,001 |
| 8 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Gene | 1989 | 7,939 |
| 9 | Mild Cognitive Impairment | Archives of Neurology | 1999 | 7,899 |
| 10 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 7,498 |
| 11 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 12 | 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults | JAMA - Journal of the American Medical Association | 2014 | 6,625 |
| 13 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 14 | Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Nature | 1993 | 6,331 |
| 15 | Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Cancer Cell | 2010 | 6,138 |
| 16 | Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2009 | 6,039 |
| 17 | NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease | Alzheimer's and Dementia | 2018 | 5,861 |
| 18 | Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial | Lancet, The | 2016 | 5,456 |
| 19 | CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials | BMJ: British Medical Journal | 2010 | 5,319 |
| 20 | 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides | Arthritis and Rheumatism | 2013 | 4,839 |
| 21 | Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus | Gut | 2013 | 4,813 |
| 22 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 23 | Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria | Lancet Neurology, The | 2018 | 4,605 |
| 24 | Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 | Journal of the American College of Cardiology | 2020 | 4,468 |
| 25 | MDS clinical diagnostic criteria for Parkinson's disease | Movement Disorders | 2015 | 4,389 |
| 26 | Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion | Nature Medicine | 2002 | 4,217 |
| 27 | Development of an upper extremity outcome measure: The DASH (disabilities of the arm, shoulder, and head) | Nature Medicine | 1996 | 4,131 |
| 28 | Mild cognitive impairment - beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment | Journal of Internal Medicine | 2004 | 4,039 |
| 29 | Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II | Arthritis and Rheumatism | 2008 | 4,029 |
| 30 | Definition and classification of cancer cachexia: an international consensus | Lancet Oncology, The | 2011 | 4,015 |
| 31 | The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging | Ca-A Cancer Journal for Clinicians | 2017 | 3,940 |
| 32 | Postoperative pancreatic fistula: An international study group (ISGPF) definition | Surgery | 2005 | 3,894 |
| 33 | The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes | Blood | 2009 | 3,864 |
| 34 | Burden of valvular heart diseases: a population-based study | Lancet, The | 2006 | 3,825 |
| 35 | Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging | Journal of the American Society of Echocardiography | 2016 | 3,807 |
| 36 | Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade | Lancet Neurology, The | 2010 | 3,792 |
| 37 | Clinical Rating Systems for the Ankle-Hindfoot, Midfoot, Hallux, and Lesser Toes | Foot and Ankle International | 1994 | 3,774 |
| 38 | Prevention of Venous Thromboembolism | Chest | 2008 | 3,752 |
| 39 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 40 | scikit-image: image processing in Python | PeerJ | 2014 | 3,711 |
| 41 | -Cell Deficit and Increased -Cell Apoptosis in Humans With Type 2 Diabetes | Diabetes | 2003 | 3,615 |
| 42 | Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles | Neuron | 2003 | 3,609 |
| 43 | Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment | Lancet, The | 2003 | 3,379 |
| 44 | Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers | Lancet Neurology, The | 2013 | 3,378 |
| 45 | International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma | Lancet Oncology, The | 2014 | 3,343 |
| 46 | Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 | Nature | 1998 | 3,333 |
| 47 | National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. Diagnosis and Staging Working Group Report | Biology of Blood and Marrow Transplantation | 2005 | 3,213 |
| 48 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 49 | PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma | New England Journal of Medicine | 2015 | 3,099 |
| 50 | Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases | Hepatology | 2018 | 3,096 |
