| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis | Nature | 2012 | 3,646 |
| 3 | European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease | Journal of Pediatric Gastroenterology and Nutrition | 2012 | 2,124 |
| 4 | Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans | Journal of Lipid Research | 2005 | 2,001 |
| 5 | HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease | Nature | 1993 | 1,837 |
| 6 | Subclinical Atrial Fibrillation and the Risk of Stroke | New England Journal of Medicine | 2012 | 1,751 |
| 7 | 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2013 | 1,705 |
| 8 | The Biodiversity of the Mediterranean Sea: Estimates, Patterns, and Threats | PLoS ONE | 2010 | 1,439 |
| 9 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 10 | Mediterranean diet pyramid today. Science and cultural updates | Public Health Nutrition | 2011 | 1,259 |
| 11 | CO2CONCENTRATING MECHANISMS IN ALGAE: Mechanisms, Environmental Modulation, and Evolution | Annual Review of Plant Biology | 2005 | 1,238 |
| 12 | Plasticenta: First evidence of microplastics in human placenta | Environment International | 2021 | 1,225 |
| 13 | Enteral Nutrient Supply for Preterm Infants: Commentary From the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition | Journal of Pediatric Gastroenterology and Nutrition | 2010 | 1,206 |
| 14 | Diagnosis and Complications of Cushing’s Syndrome: A Consensus Statement | Journal of Clinical Endocrinology and Metabolism | 2003 | 1,184 |
| 15 | Cholangiocarcinoma 2020: the next horizon in mechanisms and management | Nature Reviews Gastroenterology and Hepatology | 2020 | 1,155 |
| 16 | Scientists’ warning to humanity: microorganisms and climate change | Nature Reviews Microbiology | 2019 | 1,138 |
| 17 | Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale | European Journal of Pain | 2004 | 1,090 |
| 18 | Current approaches to diagnosis and treatment of celiac disease: An evolving spectrum | Gastroenterology | 2001 | 1,077 |
| 19 | Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice | Cell | 2004 | 1,074 |
| 20 | Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss | Diabetes | 2005 | 992 |
| 21 | Pollutants bioavailability and toxicological risk from microplastics to marine mussels | Environmental Pollution | 2015 | 989 |
| 22 | Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone | Carbohydrate Polymers | 2009 | 970 |
| 23 | Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) | Nature Reviews Gastroenterology and Hepatology | 2016 | 964 |
| 24 | Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis | Clinical Gastroenterology and Hepatology | 2018 | 908 |
| 25 | Plastics and microplastics in the oceans: From emerging pollutants to emerged threat | Marine Environmental Research | 2017 | 815 |
| 26 | Modeling of carrier mobility against carrier concentration in arsenic-, phosphorus-, and boron-doped silicon | IEEE Transactions on Electron Devices | 1983 | 813 |
| 27 | European Consensus Guidelines on the Management of Respiratory Distress Syndrome – 2019 Update | Neonatology | 2019 | 780 |
| 28 | Treatment of Adrenocorticotropin-Dependent Cushing’s Syndrome: A Consensus Statement | Journal of Clinical Endocrinology and Metabolism | 2008 | 774 |
| 29 | beta AR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance | Science | 2002 | 738 |
| 30 | A Survey on Adrenal Incidentaloma in Italy | Journal of Clinical Endocrinology and Metabolism | 2000 | 723 |
| 31 | Sulfur Assimilation in Photosynthetic Organisms: Molecular Functions and Regulations of Transporters and Assimilatory Enzymes | Annual Review of Plant Biology | 2011 | 720 |
| 32 | Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch | Cell | 2014 | 719 |
| 33 | The strawberry: Composition, nutritional quality, and impact on human health | Nutrition | 2012 | 695 |
| 34 | A Survey on Adrenal Incidentaloma in Italy1 | Journal of Clinical Endocrinology and Metabolism | 2000 | 693 |
| 35 | Autologous Transplantation and Maintenance Therapy in Multiple Myeloma | New England Journal of Medicine | 2014 | 683 |
| 36 | Oxidative pathways of chemical toxicity and oxidative stress biomarkers in marine organisms | Marine Environmental Research | 2014 | 663 |
| 37 | Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene | Nature Neuroscience | 2001 | 661 |
| 38 | The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project | Annals of Medicine | 2010 | 658 |
| 39 | Coeliac disease in the year 2000: exploring the iceberg | Lancet, The | 1994 | 650 |
| 40 | Exponential Decline of Deep-Sea Ecosystem Functioning Linked to Benthic Biodiversity Loss | Current Biology | 2008 | 641 |
| 41 | Deep, diverse and definitely different: unique attributes of the world's largest ecosystem | Biogeosciences | 2010 | 619 |
| 42 | The African coelacanth genome provides insights into tetrapod evolution | Nature | 2013 | 612 |
| 43 | Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle | Cell Metabolism | 2005 | 608 |
| 44 | Genipin-crosslinked chitosan hydrogels as biomedical and pharmaceutical aids | Carbohydrate Polymers | 2009 | 596 |
| 45 | Current views on fungal chitin/chitosan, human chitinases, food preservation, glucans, pectins and inulin: A tribute to Henri Braconnot, precursor of the carbohydrate polymers science, on the chitin bicentennial | Carbohydrate Polymers | 2012 | 593 |
| 46 | Chemotherapy in Addition to Supportive Care Improves Survival in Advanced Non–Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis of Individual Patient Data From 16 Randomized Controlled Trials | Journal of Clinical Oncology | 2008 | 582 |
| 47 | Experimental development of a new protocol for extraction and characterization of microplastics in fish tissues: First observations in commercial species from Adriatic Sea | Marine Environmental Research | 2015 | 576 |
| 48 | Lipotoxicity and the gut-liver axis in NASH pathogenesis | Journal of Hepatology | 2018 | 566 |
| 49 | Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis | New England Journal of Medicine | 2006 | 549 |
| 50 | p63 Is a Prostate Basal Cell Marker and Is Required for Prostate Development | American Journal of Pathology | 2000 | 538 |
