| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events | Journal of Clinical Sleep Medicine | 2012 | 3,887 |
| 4 | ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology | Epilepsia | 2017 | 3,464 |
| 5 | T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial | Lancet, The | 2015 | 2,476 |
| 6 | Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene | Science | 1996 | 2,365 |
| 7 | Identification of FAP locus genes from chromosome 5q21 | Science | 1991 | 2,257 |
| 8 | MicroRNAs and other non-coding RNAs as targets for anticancer drug development | Nature Reviews Drug Discovery | 2013 | 1,234 |
| 9 | The International Neuroblastoma Pathology Classification (the Shimada system) | Cancer | 1999 | 940 |
| 10 | MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients | Blood | 2005 | 894 |
| 11 | Induction of Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells by Transforming Growth Factor-β1 | American Journal of Pathology | 2005 | 871 |
| 12 | A meta-analytic review of achievement goal measures: Different labels for the same constructs or different constructs with similar labels? | Psychological Bulletin | 2010 | 865 |
| 13 | Structural evidence for the authenticity of the human retinoblastoma gene | Science | 1987 | 782 |
| 14 | The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis? | International Journal of Biochemistry and Cell Biology | 2008 | 781 |
| 15 | Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting | European Journal of Endocrinology | 2017 | 771 |
| 16 | Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome | JAMA Pediatrics | 2017 | 749 |
| 17 | Normal Polysomnographic Values for Children and Adolescents | The American Review of Respiratory Disease | 1992 | 729 |
| 18 | Acute leukaemia in bcr/abl transgenic mice | Nature | 1990 | 686 |
| 19 | A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan | Cell Metabolism | 2015 | 635 |
| 20 | Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands | Nature Genetics | 2017 | 624 |
| 21 | DNA methylation decreases in aging but not in immortal cells | Science | 1983 | 621 |
| 22 | Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo | Nature Biotechnology | 2010 | 618 |
| 23 | Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials | Lancet Oncology, The | 2020 | 608 |
| 24 | Tolerance limits and methodologies for IMRT measurement‐based verification QA: Recommendations of AAPM Task Group No. 218 | Medical Physics | 2018 | 600 |
| 25 | Terminology and morphologic criteria of neuroblastic tumors | Cancer | 1999 | 583 |
| 26 | GAPS IN DOCTOR-PATIENT COMMUNICATION | Pediatrics | 1968 | 571 |
| 27 | Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children | Pediatric Critical Care Medicine | 2020 | 567 |
| 28 | Sequence-Specific Knockdown of EWS-FLI1 by Targeted, Nonviral Delivery of Small Interfering RNA Inhibits Tumor Growth in a Murine Model of Metastatic Ewing's Sarcoma | Cancer Research | 2005 | 560 |
| 29 | Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells | PLoS ONE | 2012 | 541 |
| 30 | Image processing and analysis methods for the Adolescent Brain Cognitive Development Study | NeuroImage | 2019 | 539 |
| 31 | MDR1 Gene Expression in Brain of Patients with Medically Intractable Epilepsy | Epilepsia | 1995 | 537 |
| 32 | Intraocular Retinoblastoma: the Case for a New Group Classification | Ophthalmology Clinics of North America | 2005 | 536 |
| 33 | Brain charts for the human lifespan | Nature | 2022 | 518 |
| 34 | MRI detects myocardial iron in the human heart | Magnetic Resonance in Medicine | 2006 | 509 |
| 35 | The PedsQLTM in Type 1 and Type 2 Diabetes: Reliability and validity of the Pediatric Quality of Life InventoryTM Generic Core Scales and Type 1 Diabetes Module | Diabetes Care | 2003 | 508 |
| 36 | Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation | Blood | 2013 | 507 |
| 37 | X-LINKED RECESSIVE PROGRESSIVE COMBINED VARIABLE IMMUNODEFICIENCY (DUNCAN'S DISEASE) | Lancet, The | 1975 | 500 |
| 38 | Langerhans cell histiocytosis (LCH): Guidelines for diagnosis, clinical work‐up, and treatment for patients till the age of 18 years | Pediatric Blood and Cancer | 2013 | 496 |
| 39 | Development of the Cerebral Cortex across Adolescence: A Multisample Study of Inter-Related Longitudinal Changes in Cortical Volume, Surface Area, and Thickness | Journal of Neuroscience | 2017 | 496 |
| 40 | Traffic-Related Air Pollution, Particulate Matter, and Autism | JAMA Psychiatry | 2013 | 495 |
| 41 | Complications of Growing-Rod Treatment for Early-Onset Scoliosis | Journal of Bone and Joint Surgery - Series A | 2010 | 488 |
| 42 | TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA | EMBO Journal | 2007 | 479 |
| 43 | Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens | Journal of Clinical Microbiology | 2016 | 449 |
| 44 | Expression and amplification of the N-myc gene in primary retinoblastoma | Nature | 1984 | 443 |
| 45 | The Varni/Thompson Pediatrie Pain Questionnaire. I. Chronic musculoskeletal pain in juvenile rheumatoid arthritis | Pain | 1987 | 442 |
| 46 | The pediatric preclinical testing program: Description of models and early testing results | Pediatric Blood and Cancer | 2007 | 430 |
| 47 | Clinical and preclinical photodynamic therapy | Lasers in Surgery and Medicine | 1995 | 428 |
| 48 | β cell replication is the primary mechanism for maintaining postnatal β cell mass | Journal of Clinical Investigation | 2004 | 427 |
| 49 | Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study | Lancet Oncology, The | 2018 | 419 |
| 50 | Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group | Epilepsia Open | 2018 | 412 |
