| # | Title | Journal | Year | Citations |
|---|
| 1 | The Structure of Haplotype Blocks in the Human Genome | Science | 2002 | 5,300 |
| 2 | Osteoporosis Prevention, Diagnosis, and Therapy | JAMA - Journal of the American Medical Association | 2001 | 4,054 |
| 3 | Replicating genotype–phenotype associations | Nature | 2007 | 1,509 |
| 4 | Genome-wide association study identifies 30 loci associated with bipolar disorder | Nature Genetics | 2019 | 1,191 |
| 5 | The State of US Health, 1990-2016 | JAMA - Journal of the American Medical Association | 2018 | 1,042 |
| 6 | A variant in CDKAL1 influences insulin response and risk of type 2 diabetes | Nature Genetics | 2007 | 966 |
| 7 | Calcium plus Vitamin D Supplementation and the Risk of Colorectal Cancer | New England Journal of Medicine | 2006 | 907 |
| 8 | Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies | Lancet, The | 2018 | 858 |
| 9 | Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy | New England Journal of Medicine | 2012 | 851 |
| 10 | The influence of technology anxiety on consumer use and experiences with self-service technologies | Journal of Business Research | 2003 | 773 |
| 11 | Effect of Hydroxyurea on Mortality and Morbidity in Adult Sickle Cell Anemia | JAMA - Journal of the American Medical Association | 2003 | 741 |
| 12 | Toxicity Testing in the 21st Century: A Vision and a Strategy | Journal of Toxicology and Environmental Health - Part B: Critical Reviews | 2010 | 724 |
| 13 | Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo | ACS Nano | 2012 | 724 |
| 14 | Low-Fat Dietary Pattern and Risk of Invasive Breast Cancer | JAMA - Journal of the American Medical Association | 2006 | 696 |
| 15 | Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes | Nature Genetics | 2007 | 670 |
| 16 | Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG) | Lancet, The | 2011 | 647 |
| 17 | Measures of response agreement for qualitative data: Some generalizations and alternatives. | Psychological Bulletin | 1971 | 609 |
| 18 | GABA-modulating bacteria of the human gut microbiota | Nature Microbiology | 2019 | 590 |
| 19 | Estrogen plus Progestin and Colorectal Cancer in Postmenopausal Women | New England Journal of Medicine | 2004 | 585 |
| 20 | Temperature dependence of the low‐ and high‐frequency Raman scattering from liquid water | Journal of Chemical Physics | 1986 | 558 |
| 21 | 2.5-million-year-old stone tools from Gona, Ethiopia | Nature | 1997 | 553 |
| 22 | Preparation of anhydrous lanthanide halides, especially iodides | Journal of Inorganic and Nuclear Chemistry | 1962 | 541 |
| 23 | Ethnicity and Breast Cancer: Factors Influencing Differences in Incidence and Outcome | Journal of the National Cancer Institute | 2005 | 539 |
| 24 | Techniques for physicochemical characterization of nanomaterials | Biotechnology Advances | 2014 | 497 |
| 25 | Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution | Nature Genetics | 2007 | 485 |
| 26 | Organization of the amygdalopetal projections from modality-specific cortical association areas in the monkey | Journal of Comparative Neurology | 1980 | 483 |
| 27 | A review of selected optimal power flow literature to 1993. II. Newton, linear programming and interior point methods | IEEE Transactions on Power Systems | 1999 | 482 |
| 28 | Postmodernism and Gender Relations in Feminist Theory | Signs | 1987 | 471 |
| 29 | Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia | Nature Genetics | 2002 | 469 |
| 30 | Skin pigmentation, biogeographical ancestry and admixture mapping | Human Genetics | 2003 | 458 |
| 31 | Discovery of the Presence and Functional Expression of Cannabinoid CB2 Receptors in Brain | Annals of the New York Academy of Sciences | 2006 | 457 |
| 32 | Control of Confounding of Genetic Associations in Stratified Populations | American Journal of Human Genetics | 2003 | 456 |
| 33 | Biotic enhancement of weathering and the habitability of Earth | Nature | 1989 | 391 |
| 34 | The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans | Brain Structure and Function | 2010 | 377 |
| 35 | More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis | Chemical Senses | 2020 | 375 |
| 36 | Physiological Responses to Racism and Discrimination: An Assessment of the Evidence | American Journal of Public Health | 2003 | 366 |
| 37 | Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ϵ4, and the Risk of Late-Onset Alzheimer Disease in African Americans | JAMA - Journal of the American Medical Association | 2013 | 360 |
| 38 | Theory of Games and Statistical Decisions. | Journal of the Royal Statistical Society Series A (General) | 1955 | 350 |
| 39 | A Genome-Wide Association Study of Hypertension and Blood Pressure in African Americans | PLoS Genetics | 2009 | 348 |
| 40 | Ultrasmall Gold Nanoparticles as Carriers for Nucleus-Based Gene Therapy Due to Size-Dependent Nuclear Entry | ACS Nano | 2014 | 347 |
| 41 | Statistics Anxiety: Nature, etiology, antecedents, effects, and treatments--a comprehensive review of the literature | Teaching in Higher Education | 2003 | 344 |
| 42 | Benign lipoblastomatosis.An analysis of 35 cases | Cancer | 1973 | 341 |
| 43 | Conservation of Coral Reefs after the 1998 Global Bleaching Event | Conservation Biology | 2000 | 340 |
| 44 | Characteristics of Human Erythrocyte Insulin Receptors | Diabetes | 1978 | 329 |
| 45 | Cellular forms and functions of brain microglia | Brain Research Bulletin | 1994 | 328 |
| 46 | Genome-wide association study of bipolar disorder in European American and African American individuals | Molecular Psychiatry | 2009 | 326 |
| 47 | Relationship of indoor allergen exposure to skin test sensitivity in inner-city children with asthma | Journal of Allergy and Clinical Immunology | 1998 | 318 |
| 48 | The human cadaver in the age of biomedical informatics | The Anatomical Record | 2002 | 315 |
| 49 | The Riordan group | Discrete Applied Mathematics | 1991 | 311 |
| 50 | Decreasing Uncertainties in Assessing Environmental Exposure, Risk, and Ecological Implications of Nanomaterials | Environmental Science & Technology | 2009 | 311 |
