# | Title | Journal | Year | Citations |
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1 | Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials | Lancet, The | 2014 | 1,971 |
2 | Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma | Molecular Cancer | 2006 | 1,550 |
3 | Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2 | Nature Genetics | 1996 | 1,092 |
4 | The mycobiota: interactions between commensal fungi and the host immune system | Nature Reviews Immunology | 2014 | 525 |
5 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
6 | Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 508 |
7 | C9orf72 is required for proper macrophage and microglial function in mice | Science | 2016 | 478 |
8 | Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease | Lancet Infectious Diseases, The | 2005 | 475 |
9 | Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double‐blind, placebo‐controlled study | Arthritis and Rheumatism | 2009 | 431 |
10 | Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis | Nature Neuroscience | 2014 | 398 |
11 | Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial | Lancet Neurology, The | 2012 | 354 |
12 | Elevated maternal cortisol early in pregnancy predicts third trimester levels of placental corticotropin releasing hormone (CRH): Priming the placental clock | Peptides | 2006 | 331 |
13 | Extended Rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma | Annals of Oncology | 1999 | 329 |
14 | Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation | Journal of Heart and Lung Transplantation | 2016 | 316 |
15 | Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human | Nature Genetics | 2000 | 304 |
16 | ATAXIA-TELANGIECTASIA | Pediatrics | 1958 | 294 |
17 | The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit | Nature Neuroscience | 2013 | 284 |
18 | The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative | Nature Reviews Neurology | 2016 | 274 |
19 | Pattern of perceived stress and anxiety in pregnancy predicts preterm birth. | Health Psychology | 2008 | 270 |
20 | Using the National Institutes of Health Stroke Scale | Stroke | 2017 | 261 |
21 | Commensal Fungi in Health and Disease | Cell Host and Microbe | 2017 | 258 |
22 | Angiogenesis in Endocrine Tumors | Endocrine Reviews | 2003 | 251 |
23 | C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD | Neuron | 2015 | 249 |
24 | RIGOR Guidelines: Escalating STAIR and STEPS for Effective Translational Research | Translational Stroke Research | 2013 | 240 |
25 | Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features | Cancer Research | 2001 | 238 |
26 | Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data | Lancet Neurology, The | 2018 | 229 |
27 | TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis | JAMA Neurology | 2014 | 221 |
28 | Assessment of Sinus Node Function in Patients with the Sick Sinus Syndrome | Circulation | 1972 | 220 |
29 | Revisiting Cerebral Postischemic Reperfusion Injury: New Insights in Understanding Reperfusion Failure, Hemorrhage, and Edema | International Journal of Stroke | 2015 | 204 |
30 | COVID‐19–associated Guillain‐Barré syndrome: The early pandemic experience | Muscle and Nerve | 2020 | 196 |
31 | Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: Contrasting effects of HLA-DR3 and the shared epitope alleles | Arthritis and Rheumatism | 2005 | 194 |
32 | Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes | Stroke | 2016 | 193 |
33 | Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet Neurology, The | 2018 | 193 |
34 | Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis | Lancet Neurology, The | 2016 | 187 |
35 | MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A | Science | 2018 | 187 |
36 | Persistently active neurons in human medial frontal and medial temporal lobe support working memory | Nature Neuroscience | 2017 | 185 |
37 | Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations | Modern Pathology | 2015 | 180 |
38 | A critical assessment of edaravone acute ischemic stroke efficacy trials: is edaravone an effective neuroprotective therapy? | Expert Opinion on Pharmacotherapy | 2010 | 179 |
39 | European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force—Second revision | Journal of the Peripheral Nervous System | 2021 | 176 |
40 | TDP-43 activates microglia through NF-κB and NLRP3 inflammasome | Experimental Neurology | 2015 | 174 |
41 | The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status | Genes and Immunity | 2005 | 173 |
42 | Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes | Annals of Neurology | 2015 | 171 |
43 | Temporary Emergency Guidance to US Stroke Centers During the Coronavirus Disease 2019 (COVID-19) Pandemic | Stroke | 2020 | 169 |
44 | Expression of ataxin-2 in brains from normal individuals and patients with Alzheimer's disease and spinocerebellar ataxia 2 | Annals of Neurology | 1999 | 161 |
45 | Current and future strategies for the treatment of malignant brain tumors | Annals of Neurology | 2003 | 160 |
46 | AWARE—AWAreness during REsuscitation—A prospective study | Resuscitation | 2014 | 157 |
47 | ARTERIO-VENOUS ANASTOMOSES IN LIVER, SPLEEN, AND LUNGS | American Journal of Physiology | 1947 | 153 |
48 | Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis | Tissue Antigens | 2007 | 153 |
49 | European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force—Second revision | European Journal of Neurology | 2021 | 153 |
50 | Interobserver and Intraobserver Variability of a Two-tier System for Grading Ovarian Serous Carcinoma | American Journal of Surgical Pathology | 2007 | 152 |