| # | Title | Journal | Year | Citations |
|---|
| 1 | Diet rapidly and reproducibly alters the human gut microbiome | Nature | 2014 | 7,592 |
| 2 | Angiogenesis in cancer, vascular, rheumatoid and other disease | Nature Medicine | 1995 | 7,257 |
| 3 | Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets | Cell | 2015 | 5,908 |
| 4 | Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases | Developmental Cell | 2009 | 4,757 |
| 5 | The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease | Science | 2006 | 4,472 |
| 6 | Central sensitization: Implications for the diagnosis and treatment of pain | Pain | 2011 | 3,166 |
| 7 | The NimStim set of facial expressions: Judgments from untrained research participants | Psychiatry Research | 2009 | 2,767 |
| 8 | Emerging fungal threats to animal, plant and ecosystem health | Nature | 2012 | 2,478 |
| 9 | Childhood obesity: public-health crisis, common sense cure | Lancet, The | 2002 | 2,428 |
| 10 | Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA | Cell Stem Cell | 2010 | 2,368 |
| 11 | Many roads to maturity: microRNA biogenesis pathways and their regulation | Nature Cell Biology | 2009 | 2,328 |
| 12 | Disease-Specific Induced Pluripotent Stem Cells | Cell | 2008 | 2,071 |
| 13 | Hematopoiesis: An Evolving Paradigm for Stem Cell Biology | Cell | 2008 | 2,061 |
| 14 | Consensus statement on concussion in sport—the 5thinternational conference on concussion in sport held in Berlin, October 2016 | British Journal of Sports Medicine | 2017 | 1,903 |
| 15 | Histone methylation: a dynamic mark in health, disease and inheritance | Nature Reviews Genetics | 2012 | 1,728 |
| 16 | Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report | Journal of Allergy and Clinical Immunology | 2010 | 1,614 |
| 17 | Dystrophin expression in the mdx mouse restored by stem cell transplantation | Nature | 1999 | 1,613 |
| 18 | Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management | Lancet Neurology, The | 2010 | 1,605 |
| 19 | Moyamoya Disease and Moyamoya Syndrome | New England Journal of Medicine | 2009 | 1,424 |
| 20 | AN INTRODUCTION TO TRP CHANNELS | Annual Review of Physiology | 2006 | 1,378 |
| 21 | Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9 | Nature | 2006 | 1,317 |
| 22 | Selective Blockade of MicroRNA Processing by Lin28 | Science | 2008 | 1,316 |
| 23 | The pathways of mitophagy for quality control and clearance of mitochondria | Cell Death and Differentiation | 2013 | 1,279 |
| 24 | Nanotechnological strategies for engineering complex tissues | Nature Nanotechnology | 2011 | 1,226 |
| 25 | Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism | Neuron | 2011 | 1,146 |
| 26 | Receiver-Operating Characteristic Analysis for Evaluating Diagnostic Tests and Predictive Models | Circulation | 2007 | 1,110 |
| 27 | Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene | Nature Genetics | 1997 | 1,102 |
| 28 | Viral membrane fusion | Nature Structural and Molecular Biology | 2008 | 1,060 |
| 29 | Melanocyte biology and skin pigmentation | Nature | 2007 | 1,048 |
| 30 | Innate immunity of the newborn: basic mechanisms and clinical correlates | Nature Reviews Immunology | 2007 | 1,041 |
| 31 | SWI/SNF nucleosome remodellers and cancer | Nature Reviews Cancer | 2011 | 1,035 |
| 32 | A Systematic Approach to the Plain Radiographic Evaluation of the Young Adult Hip | Journal of Bone and Joint Surgery - Series A | 2008 | 1,022 |
| 33 | The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis | Cell Metabolism | 2005 | 1,006 |
| 34 | PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility | Cell | 2011 | 997 |
| 35 | Recurrent BRAF mutations in Langerhans cell histiocytosis | Blood | 2010 | 996 |
| 36 | MITF: master regulator of melanocyte development and melanoma oncogene | Trends in Molecular Medicine | 2006 | 993 |
| 37 | Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells | Nature Biotechnology | 2009 | 985 |
| 38 | A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein Secretion Apparatus | Science | 2006 | 984 |
| 39 | Rates of medication errors among depressed and burnt out residents: prospective cohort study | BMJ: British Medical Journal | 2008 | 945 |
| 40 | Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment | Nature | 2009 | 938 |
| 41 | Prevalence of the Metabolic Syndrome in American Adolescents | Circulation | 2004 | 935 |
| 42 | Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs | Cell | 2011 | 926 |
| 43 | Biomarkers of Acute Kidney Injury | Annual Review of Pharmacology and Toxicology | 2008 | 925 |
| 44 | Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies | Epilepsia | 2008 | 914 |
| 45 | 2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host | Clinical Infectious Diseases | 2014 | 910 |
| 46 | Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart | Nature | 2008 | 905 |
| 47 | Children With Medical Complexity: An Emerging Population for Clinical and Research Initiatives | Pediatrics | 2011 | 884 |
| 48 | Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee | Journal of Clinical Immunology | 2020 | 881 |
| 49 | The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease | Annual Review of Neuroscience | 2012 | 876 |
| 50 | Halothane–Morphine Compared with High-Dose Sufentanil for Anesthesia and Postoperative Analgesia in Neonatal Cardiac Surgery | New England Journal of Medicine | 1992 | 866 |
