| # | Title | Journal | Year | Citations |
|---|
| 1 | The complete genome sequence of the Gram-positive bacterium Bacillus subtilis | Nature | 1997 | 3,519 |
| 2 | NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells | Blood | 2002 | 1,322 |
| 3 | Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction | Nature Medicine | 2006 | 1,128 |
| 4 | Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study | Lancet Oncology, The | 2014 | 1,112 |
| 5 | Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes | Nature | 1996 | 982 |
| 6 | The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. | Journal of Immunology | 1997 | 834 |
| 7 | Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa | Nature Genetics | 2019 | 641 |
| 8 | Design concepts for the Cherenkov Telescope Array CTA: an advanced facility for ground-based high-energy gamma-ray astronomy | Experimental Astronomy | 2011 | 640 |
| 9 | A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2 | Nature Genetics | 2001 | 635 |
| 10 | Engineering surface states of carbon dots to achieve controllable luminescence for solid-luminescent composites and sensitive Be2+ detection | Scientific Reports | 2014 | 544 |
| 11 | Somatic RHOA mutation in angioimmunoblastic T cell lymphoma | Nature Genetics | 2014 | 542 |
| 12 | Low-threshold cold cathodes made of nitrogen-doped chemical-vapour-deposited diamond | Nature | 1996 | 539 |
| 13 | The lectin-complement pathway - its role in innate immunity and evolution | Immunological Reviews | 2004 | 537 |
| 14 | Observation of a small atmospheric vμ/ve ratio in Kamiokande | Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | 1992 | 522 |
| 15 | Rapid increase in plasma growth hormone after low-intensity resistance exercise with vascular occlusion | Journal of Applied Physiology | 2000 | 496 |
| 16 | Nucleosynthetic signatures of the first stars | Nature | 2005 | 481 |
| 17 | Hot-Plasma Ejections Associated with Compact-Loop Solar Flares | Astrophysical Journal | 1995 | 463 |
| 18 | The pathway of auxin biosynthesis in plants | Journal of Experimental Botany | 2012 | 463 |
| 19 | Is Breast Cancer the Same Disease in Asian and Western Countries? | World Journal of Surgery | 2010 | 460 |
| 20 | The Japanese space gravitational wave antenna: DECIGO | Classical and Quantum Gravity | 2011 | 456 |
| 21 | The EarthCARE Satellite: The Next Step Forward in Global Measurements of Clouds, Aerosols, Precipitation, and Radiation | Bulletin of the American Meteorological Society | 2015 | 443 |
| 22 | Zinc oxide films prepared by sol-gel spin-coating | Thin Solid Films | 2000 | 432 |
| 23 | The timescales of subduction initiation and subsequent evolution of an oceanic island arc | Earth and Planetary Science Letters | 2011 | 415 |
| 24 | Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus | Circulation | 2019 | 415 |
| 25 | Specification for a standard procedure of X-ray diffraction measurements on carbon materials | Carbon | 2004 | 414 |
| 26 | Public spending and green economic growth in BRI region: Mediating role of green finance | Energy Policy | 2021 | 412 |
| 27 | A Japanese Lung Cancer Registry Study: Prognosis of 13,010 Resected Lung Cancers | Journal of Thoracic Oncology | 2008 | 391 |
| 28 | Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality | Nature Genetics | 2006 | 376 |
| 29 | Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation at Risk of Stroke: Perspectives from the International, Observational, Prospective GARFIELD Registry | PLoS ONE | 2013 | 375 |
| 30 | Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins | Genome Biology | 2017 | 375 |
| 31 | A Load Flow Calculation Method for Ill-Conditioned Power Systems | IEEE Transactions on Power Apparatus and Systems / Technical Operations Committee | 1981 | 358 |
| 32 | Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan | Journal of Gastroenterology | 2010 | 354 |
| 33 | A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303 | British Journal of Haematology | 2001 | 335 |
| 34 | Organ/body-on-a-chip based on microfluidic technology for drug discovery | Drug Metabolism and Pharmacokinetics | 2018 | 334 |
| 35 | Statistical Study of Solar X-Ray Jets Observed with the Yohkoh Soft X-Ray Telescope | Publication of the Astronomical Society of Japan | 1996 | 330 |
| 36 | Role of NK cells in the control of metastatic spread and growth of tumor cells in mice | International Journal of Cancer | 1982 | 326 |
| 37 | Distant metastasis of renal adenocarcinoma | Cancer | 1981 | 325 |
| 38 | High Dispersion Spectrograph (HDS) for the Subaru Telescope | Publication of the Astronomical Society of Japan | 2002 | 325 |
| 39 | Mangroves as a coastal protection from waves in the Tong King delta, Vietnam | Mangroves and Salt Marshes | 1997 | 322 |
| 40 | Digital finance, green technological innovation and energy-environmental performance: Evidence from China's regional economies | Journal of Cleaner Production | 2021 | 317 |
| 41 | Facility Hemodialysis Vascular Access Use and Mortality in Countries Participating in DOPPS: An Instrumental Variable Analysis | American Journal of Kidney Diseases | 2009 | 311 |
| 42 | Sprint performance is related to muscle fascicle length in male 100-m sprinters | Journal of Applied Physiology | 2000 | 308 |
| 43 | Addictive Personality and Problematic Mobile Phone Use | Cyberpsychology, Behavior and Social Networking | 2009 | 306 |
| 44 | Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells | Development (Cambridge) | 2002 | 305 |
| 45 | Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction | Neuroscience Research | 2006 | 300 |
| 46 | Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta | Nature Genetics | 2008 | 300 |
| 47 | Pelagic Fishing at 42,000 Years Before the Present and the Maritime Skills of Modern Humans | Science | 2011 | 298 |
| 48 | Energy efficiency: The role of technological innovation and knowledge spillover | Technological Forecasting and Social Change | 2021 | 297 |
| 49 | Spectroscopic Studies of Extremely Metal‐Poor Stars with the Subaru High Dispersion Spectrograph. II. Ther‐Process Elements, Including Thorium | Astrophysical Journal | 2004 | 294 |
| 50 | Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones | PLoS Biology | 2004 | 290 |
