| # | Title | Journal | Year | Citations |
|---|
| 1 | A microRNA expression signature of human solid tumors defines cancer gene targets | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 5,220 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 4 | Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 3,753 |
| 5 | miR-15 and miR-16 induce apoptosis by targeting BCL2 | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 3,287 |
| 6 | A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia | New England Journal of Medicine | 2005 | 2,255 |
| 7 | Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies | Lancet Oncology, The | 2011 | 1,778 |
| 8 | Occurrence of pharmaceutical compounds in urban wastewater: Removal, mass load and environmental risk after a secondary treatment—A review | Science of the Total Environment | 2012 | 1,681 |
| 9 | Electrochemical oxidation of organic pollutants for the wastewater treatment: direct and indirect processes | Chemical Society Reviews | 2006 | 1,476 |
| 10 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 11 | Activation of microglial cells by β-amyloid protein and interferon-γ | Nature | 1995 | 1,312 |
| 12 | 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 1,265 |
| 13 | MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 1,238 |
| 14 | Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019 | European Respiratory Journal | 2019 | 1,223 |
| 15 | Analysis of 14 Trials Comparing Sirolimus-Eluting Stents with Bare-Metal Stents | New England Journal of Medicine | 2007 | 1,182 |
| 16 | The Dalton quantum chemistry program system | Wiley Interdisciplinary Reviews: Computational Molecular Science | 2014 | 1,166 |
| 17 | Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice | Science | 2011 | 1,159 |
| 18 | Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels | Journal of Cell Biology | 2006 | 1,107 |
| 19 | Asthma | Lancet, The | 2018 | 1,105 |
| 20 | Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences | Physiological Reviews | 2006 | 1,067 |
| 21 | Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trial | Lancet, The | 2016 | 1,050 |
| 22 | MicroRNA Expression Patterns to Differentiate Pancreatic Adenocarcinoma From Normal Pancreas and Chronic Pancreatitis | JAMA - Journal of the American Medical Association | 2007 | 1,046 |
| 23 | Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis | Cell | 2005 | 1,041 |
| 24 | Regulation of autophagy by cytoplasmic p53 | Nature Cell Biology | 2008 | 1,025 |
| 25 | Extensive modulation of a set of microRNAs in primary glioblastoma | Biochemical and Biophysical Research Communications | 2005 | 1,009 |
| 26 | A MicroRNA Signature of Hypoxia | Molecular and Cellular Biology | 2007 | 990 |
| 27 | International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology | European Heart Journal | 2018 | 972 |
| 28 | Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies | Molecular Psychiatry | 2022 | 967 |
| 29 | Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-β, and Bcl-2 | Molecular Cell | 2007 | 961 |
| 30 | Transglutaminases: Nature’s biological glues | Biochemical Journal | 2002 | 955 |
| 31 | Role of deficient type III interferon-λ production in asthma exacerbations | Nature Medicine | 2006 | 955 |
| 32 | The P2X7 Receptor: A Key Player in IL-1 Processing and Release | Journal of Immunology | 2006 | 949 |
| 33 | Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis | Oncogene | 2008 | 944 |
| 34 | Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial | Lancet, The | 2008 | 934 |
| 35 | Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism | Nature Medicine | 2000 | 909 |
| 36 | Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation | Nature Medicine | 2006 | 870 |
| 37 | Resting Heart Rate in Cardiovascular Disease | Journal of the American College of Cardiology | 2007 | 867 |
| 38 | The P2X7 Receptor in Infection and Inflammation | Immunity | 2017 | 853 |
| 39 | E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer | Cancer Cell | 2008 | 818 |
| 40 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 | Cell Death and Differentiation | 2015 | 811 |
| 41 | Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies | Journal of Biological Regulators and Homeostatic Agents | 2020 | 783 |
| 42 | Cyclin G1 Is a Target of miR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma | Cancer Research | 2007 | 782 |
| 43 | Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine | Haematologica | 2004 | 772 |
| 44 | Nucleotide signalling during inflammation | Nature | 2014 | 750 |
| 45 | MiR-15a and miR-16-1 cluster functions in human leukemia | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 741 |
| 46 | The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB–binding protein | Nature Genetics | 1996 | 740 |
| 47 | Ranging With Ultrawide Bandwidth Signals in Multipath Environments | Proceedings of the IEEE | 2009 | 733 |
| 48 | Genomic insights into the origin of farming in the ancient Near East | Nature | 2016 | 733 |
| 49 | Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells | Nature Protocols | 2009 | 726 |
| 50 | The diagnostic criteria for small fibre neuropathy: from symptoms to neuropathology | Brain | 2008 | 707 |
