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Top Articles

#TitleJournalYearCitations
1Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2Nature Biotechnology201911,167
2Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
3Proposed minimum reporting standards for chemical analysisMetabolomics20073,589
4Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
5Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014MMWR Surveillance Summaries20182,687
6Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of AmericaClinical Infectious Diseases20082,432
7Purposeful selection of variables in logistic regressionSource Code for Biology and Medicine20082,426
8Effectiveness-implementation Hybrid DesignsMedical Care20122,409
9Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 DiabetesNew England Journal of Medicine20132,294
10Underrepresentation of Patients 65 Years of Age or Older in Cancer-Treatment TrialsNew England Journal of Medicine19992,030
11Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature CommitteeJournal of Bone and Mineral Research20132,023
12The Sentinel Node in Breast Cancer — A Multicenter Validation StudyNew England Journal of Medicine19981,907
13Cachexia: A new definitionClinical Nutrition20081,906
14Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.Proceedings of the National Academy of Sciences of the United States of America19891,695
15Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel ReportJournal of Allergy and Clinical Immunology20101,614
16Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of OsteoporosisNew England Journal of Medicine19951,601
17Nephrectomy Followed by Interferon Alfa-2b Compared with Interferon Alfa-2b Alone for Metastatic Renal-Cell CancerNew England Journal of Medicine20011,583
18New insights on trehalose: a multifunctional moleculeGlycobiology20031,577
19Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.Journal of Clinical Investigation19981,474
20Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivoJournal of Experimental Medicine20121,441
21Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
22Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research ConsortiumClinical Infectious Diseases20201,429
23Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and GenomicsGenetics in Medicine20171,398
24The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple MyelomaNew England Journal of Medicine20031,368
25A whole brain fMRI atlas generated via spatially constrained spectral clusteringHuman Brain Mapping20121,334
26Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2012MMWR Surveillance Summaries20161,306
27Mental Health Problems and Help-Seeking Behavior Among College StudentsJournal of Adolescent Health20101,288
28Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in miceNature Medicine20161,273
29Perspectives on cancer therapy-induced mucosal injuryCancer20041,214
30Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trialLancet, The20101,182
31Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/SclerostinJournal of Biological Chemistry20081,136
32Aging of skeletal muscle: a 12-yr longitudinal studyJournal of Applied Physiology20001,129
33Sugar for the brain: the role of glucose in physiological and pathological brain functionTrends in Neurosciences20131,082
34Mechanisms of HepatotoxicityToxicological Sciences20021,043
35Branched-chain amino acids in metabolic signalling and insulin resistanceNature Reviews Endocrinology20141,006
36The molecular classification of multiple myelomaBlood2006997
37Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patientsBrain2000995
38Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle ProductionScience2010948
39Maternal epigenetics and methyl supplements affectagoutigene expression inAvy/amiceFASEB Journal1998938
40Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormoneJournal of Clinical Investigation1999920
41Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple MyelomaCancer Cell2007899
42Development and Validity of a 2-Item Screen to Identify Families at Risk for Food InsecurityPediatrics2010890
43Children With Medical Complexity: An Emerging Population for Clinical and Research InitiativesPediatrics2011884
44Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer RelapseCancer Discovery2017881
45Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activityCell2001872
46ACETAMINOPHEN-INDUCED HEPATOTOXICITYDrug Metabolism and Disposition2003867
47Intertumoral Heterogeneity within Medulloblastoma SubgroupsCancer Cell2017836
48A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1Blood2007831
49Assessing the outcome of pediatric intensive careJournal of Pediatrics1992829
50Microglia and neuroinflammation: a pathological perspectiveJournal of Neuroinflammation2004825