| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Toward discovery science of human brain function | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 2,703 |
| 3 | Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis | Lancet, The | 2013 | 2,094 |
| 4 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 5 | Multiple sclerosis | Lancet, The | 2018 | 1,204 |
| 6 | Relevant Prognostic Factors in Gastric Cancer | Annals of Surgery | 1998 | 972 |
| 7 | Selective changes of resting-state networks in individuals at risk for Alzheimer's disease | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 957 |
| 8 | Evaluation of Hybrid 68Ga-PSMA Ligand PET/CT in 248 Patients with Biochemical Recurrence After Radical Prostatectomy | Journal of Nuclear Medicine | 2015 | 907 |
| 9 | Tissue-specific and inducible Cre-mediated recombination in the gut epithelium | Genesis | 2004 | 891 |
| 10 | TNM staging of midgut and hindgut (neuro) endocrine tumors: a consensus proposal including a grading system | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2007 | 877 |
| 11 | Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial | Lancet Oncology, The | 2010 | 873 |
| 12 | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses | Nature Genetics | 2016 | 870 |
| 13 | Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis | Lancet, The | 2012 | 742 |
| 14 | Borderline resectable pancreatic cancer: A consensus statement by the International Study Group of Pancreatic Surgery (ISGPS) | Surgery | 2014 | 736 |
| 15 | New generation antipsychotics versus low-potency conventional antipsychotics: a systematic review and meta-analysis | Lancet, The | 2003 | 667 |
| 16 | Diagnostic Efficacy of 68 Gallium-PSMA Positron Emission Tomography Compared to Conventional Imaging for Lymph Node Staging of 130 Consecutive Patients with Intermediate to High Risk Prostate Cancer | Journal of Urology | 2016 | 659 |
| 17 | Tuning Out the Noise: Limbic-Auditory Interactions in Tinnitus | Neuron | 2010 | 630 |
| 18 | Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy | Cancer | 2003 | 607 |
| 19 | Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients | Journal of Neuroinflammation | 2012 | 593 |
| 20 | Physical illness and schizophrenia: a review of the literature | Acta Psychiatrica Scandinavica | 2007 | 545 |
| 21 | National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers | Clinical Chemistry | 2008 | 539 |
| 22 | Intrathecal pathogenic anti–aquaporin‐4 antibodies in early neuromyelitis optica | Annals of Neurology | 2009 | 516 |
| 23 | Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study | European Journal of Nuclear Medicine and Molecular Imaging | 2003 | 510 |
| 24 | Update on the diagnosis and treatment of neuromyelitis optica: Recommendations of the Neuromyelitis Optica Study Group (NEMOS) | Journal of Neurology | 2014 | 494 |
| 25 | European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part I | European Urology | 2008 | 488 |
| 26 | Positron Emission Tomography in Non–Small-Cell Lung Cancer: Prediction of Response to Chemotherapy by Quantitative Assessment of Glucose Use | Journal of Clinical Oncology | 2003 | 480 |
| 27 | An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis | Lancet Oncology, The | 2009 | 477 |
| 28 | Event-related functional magnetic resonance imaging in Parkinson's disease before and after levodopa | Brain | 2001 | 471 |
| 29 | Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles | Pain | 2017 | 462 |
| 30 | ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis | Multiple Sclerosis Journal | 2018 | 458 |
| 31 | Simultaneous 68Ga-PSMA HBED-CC PET/MRI Improves the Localization of Primary Prostate Cancer | European Urology | 2016 | 456 |
| 32 | Amisulpride, an Unusual "Atypical" Antipsychotic: A Meta-Analysis of Randomized Controlled Trials | American Journal of Psychiatry | 2002 | 455 |
| 33 | Stromal biology and therapy in pancreatic cancer: a changing paradigm | Gut | 2015 | 444 |
| 34 | Leukemia-Associated Somatic Mutations Drive Distinct Patterns of Age-Related Clonal Hemopoiesis | Cell Reports | 2015 | 443 |
| 35 | Interleukin-6: designing specific therapeutics for a complex cytokine | Nature Reviews Drug Discovery | 2018 | 440 |
| 36 | A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis | Nature Genetics | 2015 | 435 |
| 37 | 68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies | Journal of Nuclear Medicine | 2015 | 432 |
| 38 | How smart do biomaterials need to be? A translational science and clinical point of view | Advanced Drug Delivery Reviews | 2013 | 429 |
| 39 | Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease | PLoS ONE | 2008 | 401 |
| 40 | EFNS guidelines on diagnosis and management of neuromyelitis optica | European Journal of Neurology | 2010 | 376 |
| 41 | Current trends and future perspectives of bone substitute materials – From space holders to innovative biomaterials | Journal of Cranio-Maxillo-Facial Surgery | 2012 | 367 |
| 42 | K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria | Immunity | 2016 | 364 |
| 43 | Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy | International Journal of Radiation Oncology Biology Physics | 2005 | 351 |
| 44 | Synthesis and radiopharmacology of O-(2-[18F]fluoroethyl)-L-tyrosine for tumor imaging | Journal of Nuclear Medicine | 1999 | 331 |
| 45 | Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study | Lancet Neurology, The | 2018 | 330 |
| 46 | Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers | PLoS Genetics | 2011 | 328 |
| 47 | Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy | Kidney International | 2015 | 327 |
| 48 | 2018 Annual Report of the European Liver Transplant Registry (ELTR) - 50-year evolution of liver transplantation | Transplant International | 2018 | 325 |
| 49 | Secretory factors from human adipose tissue and their functional role | Proceedings of the Nutrition Society | 2005 | 321 |
| 50 | Potassium Channel KIR4.1 as an Immune Target in Multiple Sclerosis | New England Journal of Medicine | 2012 | 314 |
