| # | Title | Journal | Year | Citations |
|---|
| 1 | Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement | Systematic Reviews | 2015 | 16,556 |
| 2 | Applications of ionic liquids in the chemical industry | Chemical Society Reviews | 2008 | 4,989 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | World Health Organization 2020 guidelines on physical activity and sedentary behaviour | British Journal of Sports Medicine | 2020 | 4,050 |
| 5 | 5-Fluorouracil: mechanisms of action and clinical strategies | Nature Reviews Cancer | 2003 | 4,015 |
| 6 | QuPath: Open source software for digital pathology image analysis | Scientific Reports | 2017 | 3,854 |
| 7 | CHEMISTRY: Ionic Liquids--Solvents of the Future? | Science | 2003 | 3,722 |
| 8 | An axiomatic basis for computer programming | Communications of the ACM | 1969 | 3,676 |
| 9 | Cancer drug resistance: an evolving paradigm | Nature Reviews Cancer | 2013 | 3,667 |
| 10 | Metal-organic frameworks | Chemical Society Reviews | 2003 | 3,163 |
| 11 | Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials | Lancet, The | 2011 | 3,080 |
| 12 | Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease | Nature Genetics | 2009 | 2,697 |
| 13 | Ionic liquids. Green solvents for the future | Pure and Applied Chemistry | 2000 | 2,545 |
| 14 | PLUMED 2: New feathers for an old bird | Computer Physics Communications | 2014 | 2,454 |
| 15 | Recent developments in Geant4 | Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment | 2016 | 2,327 |
| 16 | Mechanochemistry: opportunities for new and cleaner synthesis | Chemical Society Reviews | 2012 | 2,281 |
| 17 | Present and Future of Surface-Enhanced Raman Scattering | ACS Nano | 2020 | 2,153 |
| 18 | Influence of chloride, water, and organic solvents on the physical properties of ionic liquids | Pure and Applied Chemistry | 2000 | 2,126 |
| 19 | Amyloid deposition as the central event in the aetiology of Alzheimer's disease | Trends in Pharmacological Sciences | 1991 | 2,091 |
| 20 | Nano-optics of surface plasmon polaritons | Physics Reports | 2005 | 2,082 |
| 21 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 22 | Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease | Nature | 2003 | 1,980 |
| 23 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 24 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,937 |
| 25 | The distillation and volatility of ionic liquids | Nature | 2006 | 1,926 |
| 26 | The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences | Nature | 2000 | 1,869 |
| 27 | Global surveillance of cancer survival 1995–2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2) | Lancet, The | 2015 | 1,863 |
| 28 | Ionic Liquids for Clean Technology | Journal of Chemical Technology and Biotechnology | 1997 | 1,857 |
| 29 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 30 | The Interleukin-8 Pathway in Cancer | Clinical Cancer Research | 2008 | 1,747 |
| 31 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 32 | The Complete Light-curve Sample of Spectroscopically Confirmed SNe Ia from Pan-STARRS1 and Cosmological Constraints from the Combined Pantheon Sample | Astrophysical Journal | 2018 | 1,694 |
| 33 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 34 | Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study | Lancet, The | 2009 | 1,524 |
| 35 | Moderate Hypothermia to Treat Perinatal Asphyxial Encephalopathy | New England Journal of Medicine | 2009 | 1,471 |
| 36 | Preferred Reporting Items for a Systematic Review and Meta-analysis of Individual Participant Data | JAMA - Journal of the American Medical Association | 2015 | 1,465 |
| 37 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2013 | 1,439 |
| 38 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 39 | Cell-Free Massive MIMO Versus Small Cells | IEEE Transactions on Wireless Communications | 2017 | 1,399 |
| 40 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 41 | Cystic fibrosis | Lancet, The | 2016 | 1,309 |
| 42 | Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508delCFTR | New England Journal of Medicine | 2015 | 1,308 |
| 43 | Molecular mechanisms of drug resistance | Journal of Pathology | 2005 | 1,270 |
| 44 | Developing core outcome sets for clinical trials: issues to consider | Trials | 2012 | 1,226 |
| 45 | Resolution of the Early Placental Mammal Radiation Using Bayesian Phylogenetics | Science | 2001 | 1,215 |
| 46 | Clinical Classification of Age-related Macular Degeneration | Ophthalmology | 2013 | 1,212 |
| 47 | Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes | World Journal of Gastroenterology | 2018 | 1,136 |
| 48 | The COMET Handbook: version 1.0 | Trials | 2017 | 1,128 |
| 49 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 50 | Clinical relevance of the ESKAPE pathogens | Expert Review of Anti-Infective Therapy | 2013 | 1,064 |
