| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria | Lancet Neurology, The | 2018 | 4,605 |
| 3 | Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 | Journal of the American College of Cardiology | 2020 | 4,468 |
| 4 | Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration | Lancet Neurology, The | 2013 | 3,919 |
| 5 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 6 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 7 | Updated Clinical Classification of Pulmonary Hypertension | Journal of the American College of Cardiology | 2013 | 2,865 |
| 8 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 9 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 10 | The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles | International Journal of Nanomedicine | 2012 | 1,823 |
| 11 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 12 | Zika Virus Infection in Pregnant Women in Rio de Janeiro | New England Journal of Medicine | 2016 | 1,816 |
| 13 | EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016 | European Urology | 2017 | 1,594 |
| 14 | European Position Paper on Rhinosinusitis and Nasal Polyps 2020 | Rhinology | 2020 | 1,555 |
| 15 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 16 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 17 | Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders | Journal of Crohn's and Colitis | 2017 | 1,324 |
| 18 | Neurofilaments as biomarkers in neurological disorders | Nature Reviews Neurology | 2018 | 1,177 |
| 19 | Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours | Journal of Pathology | 2014 | 1,151 |
| 20 | Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase | Science | 2006 | 1,135 |
| 21 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 22 | Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force | Annals of the Rheumatic Diseases | 2016 | 1,114 |
| 23 | Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline | Endoscopy | 2015 | 1,112 |
| 24 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 25 | 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus | Arthritis and Rheumatology | 2019 | 1,098 |
| 26 | EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013 | European Urology | 2013 | 1,053 |
| 27 | Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels With All-Cause and Cardiovascular Mortality | Archives of Internal Medicine | 2008 | 1,027 |
| 28 | The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria | Allergy: European Journal of Allergy and Clinical Immunology | 2018 | 1,008 |
| 29 | Diagnosis and Assessment of Pulmonary Arterial Hypertension | Journal of the American College of Cardiology | 2009 | 984 |
| 30 | Vitamin D deficiency in Europe: pandemic? | American Journal of Clinical Nutrition | 2016 | 963 |
| 31 | Diagnosis and Management of Osteonecrosis of the Jaw: A Systematic Review and International Consensus | Journal of Bone and Mineral Research | 2015 | 957 |
| 32 | European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (TaT1 and Carcinoma In Situ) - 2019 Update | European Urology | 2019 | 936 |
| 33 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 34 | The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update | Allergy: European Journal of Allergy and Clinical Immunology | 2014 | 912 |
| 35 | Current and future perspectives of liquid biopsies in genomics-driven oncology | Nature Reviews Genetics | 2019 | 912 |
| 36 | Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy | JAMA Pediatrics | 2017 | 898 |
| 37 | Chronic Thromboembolic Pulmonary Hypertension (CTEPH) | Circulation | 2011 | 860 |
| 38 | Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review | European Respiratory Journal | 2009 | 853 |
| 39 | Comparison and Evaluation of Methods for Liver Segmentation From CT Datasets | IEEE Transactions on Medical Imaging | 2009 | 848 |
| 40 | Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity | Nature Genetics | 2012 | 848 |
| 41 | The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas | Blood | 2019 | 846 |
| 42 | Colorectal polypectomy and endoscopic mucosal resection (EMR): European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline | Endoscopy | 2017 | 831 |
| 43 | Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability | Immunity | 2016 | 814 |
| 44 | Magnetic resonance imaging of the breast: Recommendations from the EUSOMA working group | European Journal of Cancer | 2010 | 813 |
| 45 | Gestational diabetes mellitus | Nature Reviews Disease Primers | 2019 | 811 |
| 46 | Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding | Journal of the American College of Cardiology | 2013 | 807 |
| 47 | European Association of Urology Guidelines on Upper Urinary Tract Urothelial Cell Carcinoma: 2015 Update | European Urology | 2015 | 804 |
| 48 | Cardioprotection and lifespan extension by the natural polyamine spermidine | Nature Medicine | 2016 | 801 |
| 49 | Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE) | European Heart Journal | 2003 | 800 |
| 50 | Placental Origins of Preeclampsia | Hypertension | 2008 | 796 |
