| # | Title | Journal | Year | Citations |
|---|
| 1 | International Physical Activity Questionnaire: 12-Country Reliability and Validity | Medicine and Science in Sports and Exercise | 2003 | 14,285 |
| 2 | Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB | Applied and Environmental Microbiology | 2006 | 9,859 |
| 3 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 4 | Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 9,122 |
| 5 | MEME SUITE: tools for motif discovery and searching | Nucleic Acids Research | 2009 | 8,180 |
| 6 | Signatures of mutational processes in human cancer | Nature | 2013 | 8,060 |
| 7 | Ecological responses to recent climate change | Nature | 2002 | 7,926 |
| 8 | CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes | Genome Research | 2015 | 7,539 |
| 9 | Finding the missing heritability of complex diseases | Nature | 2009 | 7,490 |
| 10 | Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes | New England Journal of Medicine | 2008 | 6,447 |
| 11 | Cell Death: The Significance of Apoptosis | International Review of Cytology | 1980 | 6,434 |
| 12 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 13 | Approved Lists of Bacterial Names | International Journal of Systematic and Evolutionary Microbiology | 1980 | 6,087 |
| 14 | Taxonomic Note: A Place for DNA-DNA Reassociation and 16S rRNA Sequence Analysis in the Present Species Definition in Bacteriology | International Journal of Systematic and Evolutionary Microbiology | 1994 | 5,819 |
| 15 | Integrative analysis of 111 reference human epigenomes | Nature | 2015 | 5,653 |
| 16 | Long non-coding RNAs: insights into functions | Nature Reviews Genetics | 2009 | 5,105 |
| 17 | The use of the area under the ROC curve in the evaluation of machine learning algorithms | Pattern Recognition | 1997 | 5,024 |
| 18 | Analysis of XPS spectra of Fe2+ and Fe3+ ions in oxide materials | Applied Surface Science | 2008 | 4,764 |
| 19 | A scheme for efficient quantum computation with linear optics | Nature | 2001 | 4,737 |
| 20 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 21 | Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data | Lancet, The | 2006 | 4,677 |
| 22 | Coral Reefs Under Rapid Climate Change and Ocean Acidification | Science | 2007 | 4,578 |
| 23 | Hyperglycemia and Adverse Pregnancy Outcomes | New England Journal of Medicine | 2008 | 4,444 |
| 24 | Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 | Lancet, The | 2017 | 4,187 |
| 25 | Top 10 algorithms in data mining | Knowledge and Information Systems | 2008 | 4,153 |
| 26 | LD Score regression distinguishes confounding from polygenicity in genome-wide association studies | Nature Genetics | 2015 | 3,905 |
| 27 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 28 | Guidance for conducting systematic scoping reviews | International Journal of Evidence-Based Healthcare | 2015 | 3,820 |
| 29 | Anatase TiO2 single crystals with a large percentage of reactive facets | Nature | 2008 | 3,753 |
| 30 | Global Biodiversity: Indicators of Recent Declines | Science | 2010 | 3,642 |
| 31 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 32 | Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 | Nature | 1998 | 3,333 |
| 33 | Interferon-γ: an overview of signals, mechanisms and functions | Journal of Leukocyte Biology | 2004 | 3,315 |
| 34 | Using social and behavioural science to support COVID-19 pandemic response | Nature Human Behaviour | 2020 | 3,200 |
| 35 | Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors | Nature | 2020 | 3,133 |
| 36 | Climate Change, Human Impacts, and the Resilience of Coral Reefs | Science | 2003 | 3,124 |
| 37 | Core outcome measures for chronic pain clinical trials: IMMPACT recommendations | Pain | 2005 | 2,915 |
| 38 | Defining ‘Evolutionarily Significant Units’ for conservation | Trends in Ecology and Evolution | 1994 | 2,896 |
| 39 | Easyfig: a genome comparison visualizer | Bioinformatics | 2011 | 2,861 |
| 40 | 10 Years of GWAS Discovery: Biology, Function, and Translation | American Journal of Human Genetics | 2017 | 2,793 |
| 41 | The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures | Chemical Reviews | 2003 | 2,784 |
| 42 | The Lancet Commission on pollution and health | Lancet, The | 2018 | 2,747 |
| 43 | Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 | Journal of the American College of Cardiology | 2017 | 2,705 |
| 44 | Toward discovery science of human brain function | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 2,703 |
| 45 | Genomic analyses identify molecular subtypes of pancreatic cancer | Nature | 2016 | 2,700 |
| 46 | BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons | BMC Genomics | 2011 | 2,691 |
| 47 | International Study of the Prevalence and Outcomes of Infection in Intensive Care Units | JAMA - Journal of the American Medical Association | 2009 | 2,682 |
| 48 | American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer | Journal of Clinical Oncology | 2010 | 2,667 |
| 49 | A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of life | Nature Biotechnology | 2018 | 2,615 |
| 50 | Decontamination and disinfection of water by solar photocatalysis: Recent overview and trends | Catalysis Today | 2009 | 2,574 |
