| # | Title | Journal | Year | Citations |
|---|
| 1 | Alpha-lipoic acid as a biological antioxidant | Free Radical Biology and Medicine | 1995 | 1,709 |
| 2 | The role of oxidative stress in the onset and progression of diabetes and its complications: asummary of a Congress Series sponsored byUNESCO-MCBN, the American Diabetes Association and the German Diabetes Society | Diabetes/Metabolism Research and Reviews | 2001 | 765 |
| 3 | Major Complications, Mortality, and Resource Utilization After Open Abdominal Surgery | Annals of Surgery | 2012 | 569 |
| 4 | Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities | Nature | 2012 | 560 |
| 5 | Intramyocardial, Autologous CD34+ Cell Therapy for Refractory Angina | Circulation Research | 2011 | 433 |
| 6 | Lipoic Acid Improves Nerve Blood Flow, Reduces Oxidative Stress, and Improves Distal Nerve Conduction in Experimental Diabetic Neuropathy | Diabetes Care | 1995 | 372 |
| 7 | The Roles of Oxidative Stress and Antioxidant Treatment in Experimental Diabetic Neuropathy | Diabetes | 1997 | 357 |
| 8 | Advanced Glycation End Product-Induced Activation of NF-κB is Suppressed by α-Lipoic Acid in Cultured Endothelial Cells | Diabetes | 1997 | 349 |
| 9 | Statistical Methods in Assessing Agreement | Journal of the American Statistical Association | 2002 | 345 |
| 10 | The role of oxidative stress and NF‐κB activation in late diabetic complications | BioFactors | 1999 | 297 |
| 11 | Immunonutrition in critically ill patients: a systematic review and analysis of the literature | Intensive Care Medicine | 2008 | 272 |
| 12 | Peritoneal Catheters and Exit-Site Practices toward Optimum Peritoneal Access: 1998 Update | Peritoneal Dialysis International | 1998 | 266 |
| 13 | Relationships between plasma measures of oxidative stress and metabolic control in NIDDM | Diabetologia | 1997 | 263 |
| 14 | What is the concentration of hydrogen peroxide in blood and plasma? | Archives of Biochemistry and Biophysics | 2016 | 234 |
| 15 | Trial of oral miltefosine for visceral leishmaniasis | Lancet, The | 1998 | 222 |
| 16 | Nanotechnology: A Focus on Nanoparticles as a Drug Delivery System | Journal of NeuroImmune Pharmacology | 2006 | 222 |
| 17 | Proposal for a unified CCN nomenclature | Journal of Clinical Pathology | 2003 | 218 |
| 18 | Treatment of normal individuals with granulocyte-colony-stimulating factor: donor experiences and the effects on peripheral blood CD34+ cell counts and on the collection of peripheral blood stem cells | Transfusion | 1996 | 216 |
| 19 | Chronic Kidney Disease, Mortality, and Treatment Strategies among Patients with Clinically Significant Coronary Artery Disease | Journal of the American Society of Nephrology: JASN | 2003 | 213 |
| 20 | Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS | Journal of Immunology | 2009 | 211 |
| 21 | Immunonutrition in High‐Risk Surgical Patients | Journal of Parenteral and Enteral Nutrition | 2010 | 208 |
| 22 | Advances in lipid nanodispersions for parenteral drug delivery and targeting | Advanced Drug Delivery Reviews | 2008 | 197 |
| 23 | Hydrodynamic Modeling of Cerebrospinal Fluid Motion Within the Spinal Cavity | Journal of Biomechanical Engineering | 2001 | 192 |
| 24 | Stimulation of Glucose Uptake by the Natural Coenzyme α-Lipoic Acid/Thioctic Acid: Participation of Elements of the Insulin Signaling Pathway | Diabetes | 1996 | 191 |
| 25 | Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kB | Diabetologia | 1999 | 188 |
| 26 | Goodness-of-Fit in Generalized Nonlinear Mixed-Effects Models | Biometrics | 1996 | 186 |
| 27 | A Randomized, Controlled Pilot Study of Autologous CD34+ Cell Therapy for Critical Limb Ischemia | Circulation: Cardiovascular Interventions | 2012 | 170 |
| 28 | Gel Scaffolds of BMP‐2‐Binding Peptide Amphiphile Nanofibers for Spinal Arthrodesis | Advanced Healthcare Materials | 2015 | 154 |
| 29 | Overexpression of E2F‐1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo | Nature Medicine | 1998 | 153 |
| 30 | Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature | Intensive Care Medicine | 2008 | 153 |
| 31 | α-Lipoic acid reduction by mammalian cells to the dithiol form, and release into the culture medium | Biochemical Pharmacology | 1994 | 148 |
| 32 | Effects of α-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids | Diabetologia | 1998 | 146 |
| 33 | Efficacy and safety of OBI‐1, an antihaemophilic factor VIII (recombinant), porcine sequence, in subjects with acquired haemophilia A | Haemophilia | 2015 | 143 |
| 34 | Feedstock material property – process relationships in fused deposition of ceramics (FDC) | Rapid Prototyping Journal | 2000 | 141 |
| 35 | Peritoneal membrane transport function in children receiving long-term dialysis. | Journal of the American Society of Nephrology: JASN | 1996 | 133 |
| 36 | Ether–lipid (alkyl-phospholipid) metabolism and the mechanism of action of ether–lipid analogues in Leishmania | Molecular and Biochemical Parasitology | 2000 | 132 |
| 37 | Alpha-lipoic acid: Antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy | Free Radical Biology and Medicine | 1996 | 127 |
| 38 | Cytosolic and Mitochondrial Systems for NADH- and NADPH-dependent Reduction of α-Lipoic Acid | Free Radical Biology and Medicine | 1997 | 125 |
| 39 | α-lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria | Free Radical Biology and Medicine | 1999 | 121 |
| 40 | Cumulative cost pattern comparison of prostate cancer treatments | Cancer | 2007 | 121 |
| 41 | NanoART synthesis, characterization, uptake, release and toxicology for human monocyte–macrophage drug delivery | Nanomedicine | 2009 | 116 |
| 42 | The role of mouse strain differences in the susceptibility to fibrosis: a systematic review | Fibrogenesis and Tissue Repair | 2013 | 110 |
| 43 | The competition game has changed | Business Horizons | 1975 | 108 |
| 44 | The Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS): Unifying Efforts to Inform Practice and Improve Global Outcomes in Peritoneal Dialysis | Peritoneal Dialysis International | 2016 | 107 |
| 45 | Stimulation by α-Lipoic acid of glucose transport activity in skeletal muscle of lean and obese zucker rats | Life Sciences | 1997 | 100 |
| 46 | Increased oxidative damage to all DNA bases in patients with type II diabetes mellitus | FEBS Letters | 1999 | 98 |
| 47 | Nanoformulated Antiretroviral Drug Combinations Extend Drug Release and Antiretroviral Responses in HIV-1-Infected Macrophages: Implications for NeuroAIDS Therapeutics | Journal of NeuroImmune Pharmacology | 2010 | 97 |
| 48 | DCL-Hb for trauma patients with severe hemorrhagic shock: the European "On-Scene" Multicenter Study | Intensive Care Medicine | 2003 | 91 |
| 49 | Assessment of the association between increasing membrane pore size and endotoxin permeability using a novel experimental dialysis simulation set-up | BMC Nephrology | 2018 | 91 |
| 50 | Multicenter clinical validation of an on-line monitor of dialysis adequacy. | Journal of the American Society of Nephrology: JASN | 1996 | 89 |
