| # | Title | Journal | Year | Citations |
|---|
| 1 | Global Prevalence and Major Risk Factors of Diabetic Retinopathy | Diabetes Care | 2012 | 3,439 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) | Nature | 2002 | 2,940 |
| 4 | Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 2,771 |
| 5 | Toward discovery science of human brain function | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 2,703 |
| 6 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 7 | Epidemiology and Outcome of Zygomycosis: A Review of 929 Reported Cases | Clinical Infectious Diseases | 2005 | 2,436 |
| 8 | Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial | Lancet Oncology, The | 2012 | 1,879 |
| 9 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation | Heart Rhythm | 2017 | 1,671 |
| 10 | Initiation of Atrial Fibrillation by Ectopic Beats Originating From the Pulmonary Veins | Circulation | 1999 | 1,467 |
| 11 | Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction | Journal of the American College of Cardiology | 2014 | 1,446 |
| 12 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 13 | Mesenchymal Stem Cells in the Wharton's Jelly of the Human Umbilical Cord | Stem Cells | 2004 | 1,202 |
| 14 | Direct regulation of TWIST by HIF-1α promotes metastasis | Nature Cell Biology | 2008 | 1,187 |
| 15 | Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial | Lancet, The | 2012 | 1,165 |
| 16 | Survey of Stress Reactions Among Health Care Workers Involved With the SARS Outbreak | Psychiatric Services | 2004 | 817 |
| 17 | Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6 | Lancet Oncology, The | 2015 | 786 |
| 18 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation | Europace | 2018 | 767 |
| 19 | MicroRNA Signature Predicts Survival and Relapse in Lung Cancer | Cancer Cell | 2008 | 754 |
| 20 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 21 | Association Between Nucleoside Analogues and Risk of Hepatitis B Virus–Related Hepatocellular Carcinoma Recurrence Following Liver Resection | JAMA - Journal of the American Medical Association | 2012 | 740 |
| 22 | MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis | Journal of Clinical Investigation | 2012 | 726 |
| 23 | Inflammation and the pathogenesis of atrial fibrillation | Nature Reviews Cardiology | 2015 | 688 |
| 24 | Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis | Nature Medicine | 2008 | 653 |
| 25 | NASH limits anti-tumour surveillance in immunotherapy-treated HCC | Nature | 2021 | 649 |
| 26 | Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan | New England Journal of Medicine | 2011 | 631 |
| 27 | 5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial | Lancet Oncology, The | 2016 | 623 |
| 28 | The anti-inflammatory potential of berberine in vitro and in vivo | Cancer Letters | 2004 | 593 |
| 29 | Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma | Clinical Cancer Research | 2008 | 592 |
| 30 | Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells | Stem Cells | 2008 | 586 |
| 31 | Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions | Pharmacogenetics and Genomics | 2006 | 583 |
| 32 | Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition | Nature Cell Biology | 2010 | 583 |
| 33 | Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2015 | 574 |
| 34 | The IASP classification of chronic pain for ICD-11: chronic neuropathic pain | Pain | 2019 | 571 |
| 35 | Sorafenib or placebo plus TACE with doxorubicin-eluting beads for intermediate stage HCC: The SPACE trial | Journal of Hepatology | 2016 | 567 |
| 36 | Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation | Cancer Research | 2010 | 563 |
| 37 | International survey on willingness‐to‐pay (WTP) for one additional QALY gained: what is the threshold of cost effectiveness? | Health Economics (United Kingdom) | 2010 | 560 |
| 38 | Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress | International Journal of Biochemistry and Cell Biology | 2005 | 543 |
| 39 | Eculizumab in Aquaporin-4–Positive Neuromyelitis Optica Spectrum Disorder | New England Journal of Medicine | 2019 | 536 |
| 40 | Osimertinib for pretreated EGFR Thr790Met-positive advanced non-small-cell lung cancer (AURA2): a multicentre, open-label, single-arm, phase 2 study | Lancet Oncology, The | 2016 | 533 |
| 41 | MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma | Hepatology | 2009 | 531 |
| 42 | Anti-reflecting and photonic nanostructures | Materials Science and Engineering Reports | 2010 | 531 |
| 43 | A Review of SARS-CoV-2 and the Ongoing Clinical Trials | International Journal of Molecular Sciences | 2020 | 530 |
| 44 | Diffusion Tensor Tractography Reveals Abnormal Topological Organization in Structural Cortical Networks in Alzheimer's Disease | Journal of Neuroscience | 2010 | 505 |
| 45 | Oxidative Stress, Mitochondrial DNA Mutation, and Impairment of Antioxidant Enzymes in Aging | Experimental Biology and Medicine | 2002 | 500 |
| 46 | High Frequency of Epidermal Growth Factor Receptor Mutations with Complex Patterns in Non–Small Cell Lung Cancers Related to Gefitinib Responsiveness in Taiwan | Clinical Cancer Research | 2004 | 500 |
| 47 | Initiation of Atrial Fibrillation by Ectopic Beats Originating From the Superior Vena Cava | Circulation | 2000 | 494 |
| 48 | Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC–MS/MS | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2007 | 479 |
| 49 | The HUman MicroNucleus Project—An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1999 | 464 |
| 50 | Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro | Kidney International | 1999 | 454 |
