Functional organization of the yeast proteome by systematic analysis of protein complexes | Nature | 2002 | 4K |
Comparative assessment of large-scale data sets of protein-protein interactions | Nature | 2002 | 1.9K |
Human non-synonymous SNPs: server and survey | Nucleic Acids Research | 2002 | 1.8K |
The genome sequence of the malaria mosquito Anopheles gambiae | Science | 2002 | 1.6K |
Multiple sequence alignment using ClustalW and ClustalX | Current Protocols in Bioinformatics | 2002 | 1.3K |
Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations | Journal of Molecular Biology | 2002 | 1.3K |
Histone methyltransferase activity of a Drosophila Polycomb group repressor complex | Cell | 2002 | 1.2K |
The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 778 |
Immunity-related genes and gene families in Anopheles gambiae | Science | 2002 | 743 |
Recent improvements to the SMART domain-based sequence annotation resource | Nucleic Acids Research | 2002 | 535 |
Analysis of catalytic residues in enzyme active sites | Journal of Molecular Biology | 2002 | 466 |
Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster | Science | 2002 | 455 |
Human TPX2 is required for targeting Aurora-A kinase to the spindle | Journal of Cell Biology | 2002 | 445 |
Systematic identification of novel protein domain families associated with nuclear functions | Genome Research | 2002 | 437 |
Alternative splicing and genome complexity | Nature Genetics | 2002 | 412 |
Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina | Cell | 2002 | 371 |
Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum | Science | 2002 | 368 |
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity | Nature Genetics | 2002 | 360 |
Mechanism of TrkB-mediated hippocampal long-term potentiation | Neuron | 2002 | 353 |
De novo designed peptide-based amyloid fibrils | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 351 |
Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 335 |
Reverse genetics in the mosquito Anopheles gambiae: targeted disruption of the Defensin gene | EMBO Reports | 2002 | 298 |
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome | Science | 2002 | 297 |
Association of genes to genetically inherited diseases using data mining | Nature Genetics | 2002 | 283 |
Codon-improved Cre recombinase (iCre) expression in the mouse | Genesis | 2002 | 278 |