| # | Title | Journal | Year | Citations |
|---|
| 1 | Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers | JAMA - Journal of the American Medical Association | 2017 | 1,898 |
| 2 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 3 | Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2017 | 1,376 |
| 4 | Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline | Endoscopy | 2015 | 1,112 |
| 5 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 6 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 7 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 8 | Mobilization of Bone Marrow-Derived Oct-4+ SSEA-4+ Very Small Embryonic-Like Stem Cells in Patients With Acute Myocardial Infarction | Journal of the American College of Cardiology | 2009 | 835 |
| 9 | Strict Blood-Pressure Control and Progression of Renal Failure in Children | New England Journal of Medicine | 2009 | 798 |
| 10 | Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer | New England Journal of Medicine | 2021 | 764 |
| 11 | Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 | JAMA Oncology | 2022 | 719 |
| 12 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 13 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 14 | Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis | Nature Genetics | 2015 | 529 |
| 15 | Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation | Journal of Clinical Oncology | 2014 | 523 |
| 16 | Lung cancer susceptibility locus at 5p15.33 | Nature Genetics | 2008 | 514 |
| 17 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
| 18 | Pathologic Complete Response Rates in Young Women With BRCA1-Positive Breast Cancers After Neoadjuvant Chemotherapy | Journal of Clinical Oncology | 2010 | 500 |
| 19 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 20 | Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array | Nature Genetics | 2013 | 492 |
| 21 | The complete European guidelines on phenylketonuria: diagnosis and treatment | Orphanet Journal of Rare Diseases | 2017 | 463 |
| 22 | Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma | Cell | 2019 | 430 |
| 23 | CHEK2 Is a Multiorgan Cancer Susceptibility Gene | American Journal of Human Genetics | 2004 | 426 |
| 24 | Genome-wide association study identifies three loci associated with melanoma risk | Nature Genetics | 2009 | 422 |
| 25 | A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer | Nature Genetics | 2014 | 408 |
| 26 | Rotigotine effects on early morning motor function and sleep in Parkinson's disease: A double‐blind, randomized, placebo‐controlled study (RECOVER) | Movement Disorders | 2011 | 394 |
| 27 | Entecavir for Treatment of Lamivudine-Refractory, HBeAg-Positive Chronic Hepatitis B | Gastroenterology | 2006 | 391 |
| 28 | Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian Cancer | JAMA - Journal of the American Medical Association | 2015 | 390 |
| 29 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 30 | Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: Results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structu | Arthritis and Rheumatism | 2011 | 369 |
| 31 | COVID-19: ICU delirium management during SARS-CoV-2 pandemic | Critical Care | 2020 | 368 |
| 32 | Response of Human Dental Pulp Capped with Biodentine and Mineral Trioxide Aggregate | Journal of Endodontics | 2013 | 362 |
| 33 | Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer | Nature Genetics | 2014 | 360 |
| 34 | Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair | Nature Genetics | 2015 | 357 |
| 35 | Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood – preliminary report | Leukemia | 2007 | 356 |
| 36 | Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer | Nature Genetics | 2017 | 356 |
| 37 | Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide | Colloids and Surfaces B: Biointerfaces | 2012 | 354 |
| 38 | Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis | Nature Genetics | 2013 | 339 |
| 39 | Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial | Lancet, The | 2013 | 329 |
| 40 | GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer | Nature Genetics | 2013 | 326 |
| 41 | A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 | Nature Genetics | 2010 | 321 |
| 42 | A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population | Nature Genetics | 2010 | 309 |
| 43 | International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers | International Journal of Cancer | 2008 | 306 |
| 44 | Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patients | Breast Cancer Research and Treatment | 2009 | 299 |
| 45 | A common variant on chromosome 11q13 is associated with atopic dermatitis | Nature Genetics | 2009 | 297 |
| 46 | Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer | Nature Genetics | 2017 | 289 |
| 47 | Genetic Structure of Europeans: A View from the North–East | PLoS ONE | 2009 | 279 |
| 48 | A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 | Nature Genetics | 2009 | 276 |
| 49 | The Prognostic Value of Pre-Operative and Post-Operative B-Type Natriuretic Peptides in Patients Undergoing Noncardiac Surgery | Journal of the American College of Cardiology | 2014 | 270 |
| 50 | Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population | Journal of Clinical Oncology | 2015 | 266 |
