| # | Title | Journal | Year | Citations |
|---|
| 1 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer | International Journal of Clinical Oncology | 2018 | 1,187 |
| 2 | The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019) | Hypertension Research | 2019 | 1,047 |
| 3 | The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014) | Hypertension Research | 2014 | 962 |
| 4 | Birth Weight and Risk of Type 2 Diabetes | JAMA - Journal of the American Medical Association | 2008 | 820 |
| 5 | Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update | Clinical Pharmacology and Therapeutics | 2017 | 450 |
| 6 | ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms | Nature Genetics | 2008 | 423 |
| 7 | Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study | Heart Rhythm | 2015 | 401 |
| 8 | Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2012 edited by the Japan Esophageal Society | Esophagus | 2015 | 383 |
| 9 | Vascular Inflammation and Repair | JACC: Cardiovascular Interventions | 2011 | 379 |
| 10 | Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with nonalcoholic fatty liver disease (NAFLD) | Digestive and Liver Disease | 2008 | 361 |
| 11 | Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly | Hypertension | 2010 | 334 |
| 12 | Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease | Nature Genetics | 2019 | 328 |
| 13 | Epidemiology of hypertensive disorders in pregnancy: prevalence, risk factors, predictors and prognosis | Hypertension Research | 2017 | 327 |
| 14 | Vascular Mechanobiology Endothelial Cell Responses to Fluid Shear Stress | Circulation Journal | 2009 | 318 |
| 15 | Diagnostic Criteria, Clinical Features, and Incidence of Thyroid Storm Based on Nationwide Surveys | Thyroid | 2012 | 315 |
| 16 | The ALBI grade provides objective hepatic reserve estimation across each BCLC stage of hepatocellular carcinoma | Journal of Hepatology | 2017 | 299 |
| 17 | Duration of hepatic vascular inflow clamping and survival after liver resection for hepatocellular carcinoma | British Journal of Surgery | 2011 | 294 |
| 18 | A genome-wide association study identifies three new risk loci for Kawasaki disease | Nature Genetics | 2012 | 284 |
| 19 | Randomized clinical trial of adjuvant gemcitabine chemotherapy versus observation in resected bile duct cancer | British Journal of Surgery | 2018 | 271 |
| 20 | Clinicopathological features of adult-onset neuronal intranuclear inclusion disease | Brain | 2016 | 268 |
| 21 | Bickerstaff's brainstem encephalitis and Fisher syndrome form a continuous spectrum | Journal of Neurology | 2008 | 248 |
| 22 | Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: A multicenter study | Annals of Neurology | 2015 | 248 |
| 23 | Comparison of Serum High-Molecular Weight (HMW) Adiponectin With Total Adiponectin Concentrations in Type 2 Diabetic Patients With Coronary Artery Disease Using a Novel Enzyme-Linked Immunosorbent Assay to Detect HMW Adiponectin | Diabetes | 2006 | 244 |
| 24 | Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules | International Immunology | 2004 | 243 |
| 25 | Evaluation of the effects of dapagliflozin, a sodium‐glucose co‐transporter‐2 inhibitor, on hepatic steatosis and fibrosis using transient elastography in patients with type 2 diabetes and non‐alcoholic fatty liver disease | Diabetes, Obesity and Metabolism | 2019 | 243 |
| 26 | Inflammation-Based Prognostic Score Is a Novel Predictor of Postoperative Outcome in Patients With Colorectal Cancer | Annals of Surgery | 2007 | 242 |
| 27 | Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis | Nature Genetics | 2013 | 240 |
| 28 | A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis | Nature Genetics | 2011 | 233 |
| 29 | Long-term Outcomes After Resection for Submucosal Invasive Colorectal Cancers | Gastroenterology | 2013 | 228 |
| 30 | Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity | Nature Immunology | 2008 | 219 |
| 31 | Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy | Neurology | 2016 | 210 |
| 32 | The RNA-binding protein HuD regulates neuronal cell identity and maturation | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 196 |
| 33 | Tofacitinib for refractory interstitial lung diseases in anti-melanoma differentiation-associated 5 gene antibody-positive dermatomyositis | Rheumatology | 2018 | 193 |
| 34 | The Impact of Repeated Subclinical Acute Rejection on the Progression of Chronic Allograft Nephropathy | Journal of the American Society of Nephrology: JASN | 2003 | 189 |
| 35 | A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas | Acta Neuropathologica Communications | 2016 | 189 |
| 36 | Clinical Significance of the C-Reactive Protein to Albumin Ratio for Survival After Surgery for Colorectal Cancer | Annals of Surgical Oncology | 2016 | 188 |
| 37 | Thymic Stromal Lymphopoietin Gene Promoter Polymorphisms Are Associated with Susceptibility to Bronchial Asthma | American Journal of Respiratory Cell and Molecular Biology | 2011 | 187 |
| 38 | A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 176 |
| 39 | Physiological Diagnostic Criteria for Vascular Failure | Hypertension | 2018 | 174 |
| 40 | High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD) | Circulation | 2018 | 174 |
| 41 | Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade | Nature Genetics | 2012 | 172 |
| 42 | Flow detection and calcium signalling in vascular endothelial cells | Cardiovascular Research | 2013 | 172 |
| 43 | ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype | Haematologica | 2017 | 172 |
| 44 | Treatments for esophageal cancer: a review | General Thoracic and Cardiovascular Surgery | 2013 | 165 |
| 45 | Effects of Shear Stress and Stretch on Endothelial Function | Antioxidants and Redox Signaling | 2011 | 164 |
| 46 | A novel and validated prognostic index in hepatocellular carcinoma: The inflammation based index (IBI) | Journal of Hepatology | 2012 | 164 |
| 47 | Conduction block in acute motor axonal neuropathy | Brain | 2010 | 163 |
| 48 | Nodal proteins are target antigens in Guillain‐Barré syndrome | Journal of the Peripheral Nervous System | 2012 | 162 |
| 49 | Pentax-AWS, a new videolaryngoscope, is more effective than the Macintosh laryngoscope for tracheal intubation in patients with restricted neck movements: a randomized comparative study | British Journal of Anaesthesia | 2008 | 160 |
| 50 | Spectrum of MLL2 (ALR) mutations in 110 cases of Kabuki syndrome | American Journal of Medical Genetics, Part A | 2011 | 160 |
