| # | Title | Journal | Year | Citations |
|---|
| 1 | Detecting the number of clusters of individuals using the software structure: a simulation study | Molecular Ecology | 2005 | 18,555 |
| 2 | The driving mechanisms of the carbon cycle perturbations in the late Pliensbachian (Early Jurassic) | Scientific Reports | 2019 | 9,028 |
| 3 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies | PLoS Medicine | 2007 | 7,961 |
| 4 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies | International Journal of Surgery | 2014 | 5,967 |
| 5 | Expert consensus document on arterial stiffness: methodological issues and clinical applications | European Heart Journal | 2006 | 5,012 |
| 6 | The Inflammasome | Molecular Cell | 2002 | 5,010 |
| 7 | Predicting species distribution: offering more than simple habitat models | Ecology Letters | 2005 | 4,859 |
| 8 | The Inflammasomes | Cell | 2010 | 4,781 |
| 9 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 10 | Landscape of transcription in human cells | Nature | 2012 | 4,484 |
| 11 | Gout-associated uric acid crystals activate the NALP3 inflammasome | Nature | 2006 | 4,427 |
| 12 | 2013 ESH/ESC Guidelines for the management of arterial hypertension | Journal of Hypertension | 2013 | 4,251 |
| 13 | A role for mitochondria in NLRP3 inflammasome activation | Nature | 2011 | 4,234 |
| 14 | GENCODE: The reference human genome annotation for The ENCODE Project | Genome Research | 2012 | 4,217 |
| 15 | Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration | PLoS Medicine | 2007 | 3,710 |
| 16 | The complete genome sequence of the Gram-positive bacterium Bacillus subtilis | Nature | 1997 | 3,519 |
| 17 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 18 | The size and burden of mental disorders and other disorders of the brain in Europe 2010 | European Neuropsychopharmacology | 2011 | 2,930 |
| 19 | The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) Statement | PLoS Medicine | 2015 | 2,892 |
| 20 | Predicting human resting-state functional connectivity from structural connectivity | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 2,791 |
| 21 | Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer | New England Journal of Medicine | 2004 | 2,704 |
| 22 | Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2009 | 2,644 |
| 23 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 24 | Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 | Cell Death and Differentiation | 2009 | 2,572 |
| 25 | Comparative phylogeography and postglacial colonization routes in Europe | Molecular Ecology | 1998 | 2,534 |
| 26 | Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism* | Endocrine Reviews | 1999 | 2,435 |
| 27 | Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial | Lancet, The | 2004 | 2,422 |
| 28 | Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 2,402 |
| 29 | Inhibition of death receptor signals by cellular FLIP | Nature | 1997 | 2,382 |
| 30 | GENCODE reference annotation for the human and mouse genomes | Nucleic Acids Research | 2019 | 2,350 |
| 31 | Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes | Cell | 2003 | 2,312 |
| 32 | Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica | Science | 2008 | 2,289 |
| 33 | Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria | Nature Immunology | 2001 | 2,239 |
| 34 | Biological control of soil-borne pathogens by fluorescent pseudomonads | Nature Reviews Microbiology | 2005 | 2,181 |
| 35 | Thioredoxin-interacting protein links oxidative stress to inflammasome activation | Nature Immunology | 2010 | 2,163 |
| 36 | A plate tectonic model for the Paleozoic and Mesozoic constrained by dynamic plate boundaries and restored synthetic oceanic isochrons | Earth and Planetary Science Letters | 2002 | 2,162 |
| 37 | Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus | Nature | 2005 | 2,136 |
| 38 | The Inflammasomes: Guardians of the Body | Annual Review of Immunology | 2009 | 2,082 |
| 39 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 40 | Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. | Endocrinology | 1996 | 1,980 |
| 41 | Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification | Gut | 1999 | 1,959 |
| 42 | Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits | Nature | 1994 | 1,904 |
| 43 | hierfstat, a package for r to compute and test hierarchical F-statistics | Molecular Ecology Notes | 2005 | 1,852 |
| 44 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 45 | Green’s-function approach to linear response in solids | Physical Review Letters | 1987 | 1,807 |
| 46 | Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications | European Journal of Pharmaceutics and Biopharmaceutics | 2004 | 1,792 |
| 47 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 48 | Roles of PPARs in health and disease | Nature | 2000 | 1,782 |
| 49 | Effects of sample size on the performance of species distribution models | Diversity and Distributions | 2008 | 1,771 |
| 50 | Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study | Lancet Respiratory Medicine,the | 2015 | 1,755 |
