| # | Title | Journal | Year | Citations |
|---|
| 1 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 2 | The integrated stress response | EMBO Reports | 2016 | 1,676 |
| 3 | Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2 | Journal of Biological Chemistry | 2003 | 1,473 |
| 4 | Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study | Lancet, The | 2016 | 1,414 |
| 5 | Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases | Lancet Infectious Diseases, The | 2013 | 1,328 |
| 6 | Pulmonary rehabilitation for chronic obstructive pulmonary disease | The Cochrane Library | 2015 | 1,275 |
| 7 | Embolic strokes of undetermined source: the case for a new clinical construct | Lancet Neurology, The | 2014 | 1,268 |
| 8 | Developing core outcome sets for clinical trials: issues to consider | Trials | 2012 | 1,226 |
| 9 | Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island | Nature Immunology | 2004 | 1,091 |
| 10 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 11 | A flexible R package for nonnegative matrix factorization | BMC Bioinformatics | 2010 | 1,074 |
| 12 | Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study | Lancet, The | 2020 | 935 |
| 13 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 14 | Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications | Molecular Therapy | 2015 | 877 |
| 15 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 16 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 17 | Reduced Graphene Oxide Conjugated Cu2O Nanowire Mesocrystals for High-Performance NO2 Gas Sensor | Journal of the American Chemical Society | 2012 | 706 |
| 18 | The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data | Brain Imaging and Behavior | 2014 | 696 |
| 19 | Microplastics in Sewage Sludge: Effects of Treatment | Environmental Science & Technology | 2017 | 687 |
| 20 | Preterm delivery | Lancet, The | 2002 | 652 |
| 21 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 22 | EuReCa ONE⿿27 Nations, ONE Europe, ONE Registry | Resuscitation | 2016 | 612 |
| 23 | Brain Oscillatory Substrates of Visual Short-Term Memory Capacity | Current Biology | 2009 | 606 |
| 24 | Identification of common variants associated with human hippocampal and intracranial volumes | Nature Genetics | 2012 | 594 |
| 25 | Electrolysis of low-grade and saline surface water | Nature Energy | 2020 | 579 |
| 26 | A review of methods to match building energy simulation models to measured data | Renewable and Sustainable Energy Reviews | 2014 | 544 |
| 27 | Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group | Molecular Psychiatry | 2018 | 522 |
| 28 | Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis | Cell Stem Cell | 2010 | 521 |
| 29 | Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells | Nature | 2014 | 519 |
| 30 | Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study | Lancet Respiratory Medicine,the | 2020 | 516 |
| 31 | Midwife-led continuity models versus other models of care for childbearing women | The Cochrane Library | 2016 | 494 |
| 32 | Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways | BMC Medicine | 2012 | 479 |
| 33 | The prevalence of multimorbidity in primary care and its effect on health care utilization and cost | Family Practice | 2011 | 478 |
| 34 | Algal chemodiversity and bioactivity: Sources of natural variability and implications for commercial application | Biotechnology Advances | 2011 | 463 |
| 35 | A comprehensive chemical kinetic combustion model for the four butanol isomers | Combustion and Flame | 2012 | 463 |
| 36 | The genetic architecture of the human cerebral cortex | Science | 2020 | 450 |
| 37 | Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies | Lancet Neurology, The | 2012 | 445 |
| 38 | An experimental and chemical kinetic modeling study of 1,3-butadiene combustion: Ignition delay time and laminar flame speed measurements | Combustion and Flame | 2018 | 432 |
| 39 | Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions | European Heart Journal | 2018 | 431 |
| 40 | Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche | | 2012 | 418 |
| 41 | Effect of thermal and non thermal processing technologies on the bioactive content of exotic fruits and their products: Review of recent advances | Food Research International | 2011 | 416 |
| 42 | Silver nanoparticles in the environment: Sources, detection and ecotoxicology | Science of the Total Environment | 2017 | 412 |
| 43 | Antithrombotic and Thrombolytic Therapy for Ischemic Stroke | Chest | 2012 | 401 |
| 44 | Application of a neural network technique to rainfall-runoff modelling | Journal of Hydrology | 1997 | 400 |
| 45 | Subcortical volumetric abnormalities in bipolar disorder | Molecular Psychiatry | 2016 | 400 |
| 46 | Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial | Stem Cells Translational Medicine | 2016 | 389 |
| 47 | Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies | Advanced Drug Delivery Reviews | 2015 | 382 |
| 48 | Green Innovation, Managerial Concern and Firm Performance: An Empirical Study | Business Strategy and the Environment | 2018 | 381 |
| 49 | Barriers and facilitators to healthcare workers’ adherence with infection prevention and control (IPC) guidelines for respiratory infectious diseases: a rapid qualitative evidence synthesis | The Cochrane Library | 2020 | 379 |
| 50 | Mesenchymal stem cell effects on T-cell effector pathways | Stem Cell Research and Therapy | 2011 | 377 |
