| # | Title | Journal | Year | Citations |
|---|
| 1 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology | Genetics in Medicine | 2015 | 20,455 |
| 2 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 3 | Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 9,122 |
| 4 | Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer | New England Journal of Medicine | 2012 | 6,820 |
| 5 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 6 | Surviving Sepsis Campaign | Critical Care Medicine | 2013 | 6,362 |
| 7 | Review: Knowledge Management and Knowledge Management Systems: Conceptual Foundations and Research Issues | MIS Quarterly: Management Information Systems | 2001 | 6,243 |
| 8 | Maternal and child undernutrition and overweight in low-income and middle-income countries | Lancet, The | 2013 | 5,719 |
| 9 | Perceptual symbol systems | Behavioral and Brain Sciences | 1999 | 5,024 |
| 10 | Effects of stress throughout the lifespan on the brain, behaviour and cognition | Nature Reviews Neuroscience | 2009 | 4,771 |
| 11 | Grounded Cognition | Annual Review of Psychology | 2008 | 4,768 |
| 12 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 13 | The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) | Neurology | 1991 | 4,673 |
| 14 | Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked | Science | 1997 | 4,648 |
| 15 | In vivo cancer targeting and imaging with semiconductor quantum dots | Nature Biotechnology | 2004 | 4,460 |
| 16 | Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 | Lancet, The | 2017 | 4,187 |
| 17 | Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science | Lancet Psychiatry,the | 2020 | 4,086 |
| 18 | Osteoporosis Prevention, Diagnosis, and Therapy | JAMA - Journal of the American Medical Association | 2001 | 4,054 |
| 19 | The Somatic Genomic Landscape of Glioblastoma | Cell | 2013 | 3,979 |
| 20 | Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus | Arthritis and Rheumatism | 2012 | 3,838 |
| 21 | World Society and the Nation‐State | American Journal of Sociology | 1997 | 3,721 |
| 22 | A Draft Sequence of the Neandertal Genome | Science | 2010 | 3,588 |
| 23 | Restoring function in exhausted CD8 T cells during chronic viral infection | Nature | 2006 | 3,471 |
| 24 | Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship | Clinical Infectious Diseases | 2007 | 3,390 |
| 25 | FOUNDATION FOR A GENERAL STRAIN THEORY OF CRIME AND DELINQUENCY* | Criminology | 1992 | 3,376 |
| 26 | International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma | Lancet Oncology, The | 2014 | 3,343 |
| 27 | Empathy: Its ultimate and proximate bases | Behavioral and Brain Sciences | 2002 | 3,319 |
| 28 | Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients | New England Journal of Medicine | 2019 | 3,312 |
| 29 | Cancer treatment and survivorship statistics, 2019 | Ca-A Cancer Journal for Clinicians | 2019 | 3,303 |
| 30 | Chronic systemic pesticide exposure reproduces features of Parkinson's disease | Nature Neuroscience | 2000 | 3,216 |
| 31 | An Examination of the Nature of Trust in Buyer–Seller Relationships | Journal of Marketing | 1997 | 3,146 |
| 32 | Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences | Genome Biology | 2010 | 3,082 |
| 33 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants | Lancet, The | 2011 | 3,019 |
| 34 | Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress | Science | 1997 | 2,952 |
| 35 | Mitochondrial Diseases in Man and Mouse | Science | 1999 | 2,875 |
| 36 | Maternal and child undernutrition: consequences for adult health and human capital | Lancet, The | 2008 | 2,798 |
| 37 | Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer | New England Journal of Medicine | 1996 | 2,724 |
| 38 | An mRNA Vaccine against SARS-CoV-2 — Preliminary Report | New England Journal of Medicine | 2020 | 2,719 |
| 39 | NAD(P)H Oxidase | Circulation Research | 2000 | 2,690 |
| 40 | Regime Shifts, Resilience, and Biodiversity in Ecosystem Management | Annual Review of Ecology, Evolution, and Systematics | 2004 | 2,674 |
| 41 | Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer | New England Journal of Medicine | 2017 | 2,631 |
| 42 | Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma | New England Journal of Medicine | 2019 | 2,594 |
| 43 | The Treatment-Naive Microbiome in New-Onset Crohn’s Disease | Cell Host and Microbe | 2014 | 2,582 |
| 44 | Self-Efficacy Beliefs in Academic Settings | Review of Educational Research | 1996 | 2,534 |
| 45 | The Mental Health Continuum: From Languishing to Flourishing in Life | Journal of Health and Social Behavior | 2002 | 2,534 |
| 46 | Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. | Circulation Research | 1994 | 2,512 |
| 47 | Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden | New England Journal of Medicine | 2018 | 2,469 |
| 48 | Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition | Neurosurgery | 2017 | 2,457 |
| 49 | A Clinically Based Classification System for Acute Pancreatitis | Archives of Surgery | 1993 | 2,361 |
| 50 | Dynamic functional connectivity: Promise, issues, and interpretations | NeuroImage | 2013 | 2,358 |
