| # | Title | Journal | Year | Citations |
|---|
| 1 | From ultrasoft pseudopotentials to the projector augmented-wave method | Physical Review B | 1999 | 61,625 |
| 2 | Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK | Lancet, The | 2021 | 3,887 |
| 3 | Guidance for conducting systematic scoping reviews | International Journal of Evidence-Based Healthcare | 2015 | 3,820 |
| 4 | Antibiotic resistance—the need for global solutions | Lancet Infectious Diseases, The | 2013 | 3,184 |
| 5 | Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis | Lancet Neurology, The | 2015 | 2,776 |
| 6 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 7 | Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society | European Heart Journal | 2013 | 2,132 |
| 8 | Cellular Scaling Rules for the Brains of Marsupials: Not as “Primitive” as Expected | Brain, Behavior and Evolution | 2017 | 1,761 |
| 9 | Updated methodological guidance for the conduct of scoping reviews | JBI Evidence Synthesis | 2020 | 1,717 |
| 10 | Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study | Lancet, The | 2017 | 1,634 |
| 11 | Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 | Intensive Care Medicine | 2021 | 1,503 |
| 12 | Why invest, and what it will take to improve breastfeeding practices? | Lancet, The | 2016 | 1,455 |
| 13 | Detection of a SARS-CoV-2 variant of concern in South Africa | Nature | 2021 | 1,381 |
| 14 | Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa | Nature | 1991 | 1,356 |
| 15 | Early Antiretroviral Therapy and Mortality among HIV-Infected Infants | New England Journal of Medicine | 2008 | 1,273 |
| 16 | Pre-eclampsia | Lancet, The | 2016 | 1,262 |
| 17 | The ecological limits of hydrologic alteration (ELOHA): a new framework for developing regional environmental flow standards | Freshwater Biology | 2010 | 1,227 |
| 18 | The Status of the World's Land and Marine Mammals: Diversity, Threat, and Knowledge | Science | 2008 | 1,215 |
| 19 | Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa | Nature | 2022 | 1,210 |
| 20 | Role of Biocatalysis in Sustainable Chemistry | Chemical Reviews | 2018 | 1,175 |
| 21 | Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa | Lancet, The | 2004 | 1,041 |
| 22 | The tetratricopeptide repeat: a structural motif mediating protein-protein interactions | BioEssays | 1999 | 1,040 |
| 23 | Quinoline, quinazoline and acridonealkaloids | Natural Product Reports | 2008 | 1,039 |
| 24 | TRY plant trait database – enhanced coverage and open access | Global Change Biology | 2020 | 1,038 |
| 25 | Australopithecus africanus The Man-Ape of South Africa | Nature | 1925 | 1,032 |
| 26 | Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management | European Heart Journal | 2015 | 1,024 |
| 27 | Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database | Annals of the Rheumatic Diseases | 2010 | 1,017 |
| 28 | Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials | Lancet, The | 2021 | 979 |
| 29 | Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income: findings from five birth cohort studies | Lancet, The | 2013 | 970 |
| 30 | Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium | Lancet Infectious Diseases, The | 2019 | 970 |
| 31 | Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study | Lancet, The | 2010 | 964 |
| 32 | The health and health system of South Africa: historical roots of current public health challenges | Lancet, The | 2009 | 939 |
| 33 | World Health Organization Estimates of the Global and Regional Disease Burden of 22 Foodborne Bacterial, Protozoal, and Viral Diseases, 2010: A Data Synthesis | PLoS Medicine | 2015 | 937 |
| 34 | Y chromosome sequence variation and the history of human populations | Nature Genetics | 2000 | 935 |
| 35 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 | Critical Care Medicine | 2021 | 927 |
| 36 | A Trial of a 9-Valent Pneumococcal Conjugate Vaccine in Children with and Those without HIV Infection | New England Journal of Medicine | 2003 | 926 |
| 37 | WFH Guidelines for the Management of Hemophilia, 3rd edition | Haemophilia | 2020 | 915 |
| 38 | The E factor 25 years on: the rise of green chemistry and sustainability | Green Chemistry | 2017 | 912 |
| 39 | Roadmap on structured light | Journal of Optics (United Kingdom) | 2017 | 888 |
| 40 | Fire, resprouting and variability: a recipe for grass-tree coexistence in savanna | Journal of Ecology | 2000 | 860 |
| 41 | Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis | Lancet, The | 2010 | 844 |
| 42 | Toward Principles for Enhancing the Resilience of Ecosystem Services | Annual Review of Environment and Resources | 2012 | 844 |
| 43 | Neuropathic pain: an updated grading system for research and clinical practice | Pain | 2016 | 824 |
| 44 | Sex Ratio and Local Resource Competition in a Prosimian Primate | Science | 1978 | 823 |
| 45 | Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial | Lancet, The | 2010 | 813 |
| 46 | Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants | New England Journal of Medicine | 2010 | 800 |
| 47 | Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis | Lancet, The | 2011 | 789 |
| 48 | A Practical Clinical Approach to Diagnosis of Fetal Alcohol Spectrum Disorders: Clarification of the 1996 Institute of Medicine Criteria | Pediatrics | 2005 | 779 |
| 49 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 50 | Indolizidine and quinolizidine alkaloids | Natural Product Reports | 2008 | 764 |
