| # | Title | Journal | Year | Citations |
|---|
| 1 | Endothelial cell infection and endotheliitis in COVID-19 | Lancet, The | 2020 | 5,100 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | Arthritis and Rheumatism | 2013 | 2,359 |
| 5 | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Nature Genetics | 2010 | 2,284 |
| 6 | Genomic correlates of response to CTLA-4 blockade in metastatic melanoma | Science | 2015 | 2,275 |
| 7 | The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours | European Urology | 2016 | 2,211 |
| 8 | Consensus statement on concussion in sport—the 5thinternational conference on concussion in sport held in Berlin, October 2016 | British Journal of Sports Medicine | 2017 | 1,903 |
| 9 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 10 | CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group | Lancet Oncology, The | 2006 | 1,840 |
| 11 | 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2013 | 1,705 |
| 12 | Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy | Thrombosis Research | 2020 | 1,690 |
| 13 | Comprehensive genomic profiles of small cell lung cancer | Nature | 2015 | 1,634 |
| 14 | Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial | Lancet, The | 2002 | 1,621 |
| 15 | Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma | JAMA - Journal of the American Medical Association | 2017 | 1,619 |
| 16 | An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor | Nature | 2011 | 1,514 |
| 17 | The New WHO Classification of Brain Tumours | Brain Pathology | 1993 | 1,480 |
| 18 | Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry | Nature Methods | 2014 | 1,430 |
| 19 | A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology | NeuroImage | 2014 | 1,371 |
| 20 | The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder Tumours | European Urology | 2016 | 1,323 |
| 21 | Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer | Nature Genetics | 2012 | 1,300 |
| 22 | Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy | British Heart Journal | 2001 | 1,254 |
| 23 | Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC) | Blood | 2007 | 1,243 |
| 24 | 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis | Annals of the Rheumatic Diseases | 2017 | 1,220 |
| 25 | Senescence surveillance of pre-malignant hepatocytes limits liver cancer development | Nature | 2011 | 1,208 |
| 26 | Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer | Nature Genetics | 2012 | 1,186 |
| 27 | Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria | Journal of Heart and Lung Transplantation | 2002 | 1,185 |
| 28 | Population-Based Studies on Incidence, Survival Rates, and Genetic Alterations in Astrocytic and Oligodendroglial Gliomas | Journal of Neuropathology and Experimental Neurology | 2005 | 1,174 |
| 29 | Cholangiocarcinoma 2020: the next horizon in mechanisms and management | Nature Reviews Gastroenterology and Hepatology | 2020 | 1,155 |
| 30 | European Association of Urology Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2020 Guidelines | European Urology | 2021 | 1,152 |
| 31 | Genetic Pathways to Glioblastoma | Cancer Research | 2004 | 1,137 |
| 32 | The Comprehensive Complication Index | Annals of Surgery | 2013 | 1,127 |
| 33 | A consensus document for the selection of lung transplant candidates: 2014—An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation | Journal of Heart and Lung Transplantation | 2015 | 1,121 |
| 34 | Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis | Journal of the American College of Cardiology | 2000 | 1,106 |
| 35 | Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy | JAMA - Journal of the American Medical Association | 2016 | 1,076 |
| 36 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study | Gastroenterology | 2010 | 1,056 |
| 37 | Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease | New England Journal of Medicine | 2019 | 1,025 |
| 38 | Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas | Acta Neuropathologica | 2009 | 1,020 |
| 39 | Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database | Annals of the Rheumatic Diseases | 2010 | 1,017 |
| 40 | The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition | Critical Care | 2016 | 1,014 |
| 41 | Pathophysiology of polytrauma | Injury | 2005 | 1,012 |
| 42 | The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria | Allergy: European Journal of Allergy and Clinical Immunology | 2018 | 1,008 |
| 43 | Chromosomal instability drives metastasis through a cytosolic DNA response | Nature | 2018 | 1,002 |
| 44 | Microglia: Intrinsic immuneffector cell of the brain | Brain Research Reviews | 1995 | 984 |
| 45 | EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy | Allergy: European Journal of Allergy and Clinical Immunology | 2014 | 979 |
| 46 | International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology | European Heart Journal | 2018 | 972 |
| 47 | An Analytical Solution to the Kinetics of Breakable Filament Assembly | Science | 2009 | 970 |
| 48 | Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) | Nature Reviews Gastroenterology and Hepatology | 2016 | 964 |
| 49 | How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) | European Heart Journal | 2019 | 944 |
| 50 | High-throughput oncogene mutation profiling in human cancer | Nature Genetics | 2007 | 927 |
