| # | Title | Journal | Year | Citations |
|---|
| 1 | Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes | New England Journal of Medicine | 2009 | 6,019 |
| 2 | The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society | Urology | 2003 | 2,597 |
| 3 | The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation | European Heart Journal | 2018 | 1,576 |
| 4 | Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program | Leukemia | 2003 | 1,359 |
| 5 | The biology of fracture healing | Injury | 2011 | 1,259 |
| 6 | Long-Term Outcomes with Drug-Eluting Stents versus Bare-Metal Stents in Sweden | New England Journal of Medicine | 2007 | 1,113 |
| 7 | Biological factors contributing to failures of osseointegrated oral implants, (II). Etiopathogenesis | European Journal of Oral Sciences | 1998 | 913 |
| 8 | Sarcopenia With Limited Mobility: An International Consensus | Journal of the American Medical Directors Association | 2011 | 884 |
| 9 | Swedish Rectal Cancer Trial: Long Lasting Benefits From Radiotherapy on Survival and Local Recurrence Rate | Journal of Clinical Oncology | 2005 | 753 |
| 10 | Thoracic Aortic Aneurysm and Dissection | Circulation | 2006 | 741 |
| 11 | Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI | New England Journal of Medicine | 2017 | 740 |
| 12 | Effects of Dapagliflozin on Body Weight, Total Fat Mass, and Regional Adipose Tissue Distribution in Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control on Metformin | Journal of Clinical Endocrinology and Metabolism | 2012 | 689 |
| 13 | Genome-wide association analyses identify 18 new loci associated with serum urate concentrations | Nature Genetics | 2013 | 675 |
| 14 | Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts | Breast Cancer Research | 2005 | 659 |
| 15 | Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial | Lancet Neurology, The | 2008 | 657 |
| 16 | MULTICENTER RANDOMIZED TRIAL COMPARING TACROLIMUS (FK506) AND CYCLOSPORINE IN THE PREVENTION OF RENAL ALLOGRAFT REJECTION1 | Transplantation | 1997 | 652 |
| 17 | An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans | Diabetes | 2017 | 615 |
| 18 | Gene therapy clinical trials worldwide to 2017: An update | Journal of Gene Medicine | 2018 | 612 |
| 19 | PET imaging of amyloid deposition in patients with mild cognitive impairment | Neurobiology of Aging | 2008 | 611 |
| 20 | Variation in antibiotic use in the European Union | Lancet, The | 2001 | 590 |
| 21 | Genome-wide association identifies multiple ulcerative colitis susceptibility loci | Nature Genetics | 2010 | 572 |
| 22 | Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo–purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group | Blood | 2008 | 571 |
| 23 | A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose | PLoS Genetics | 2009 | 554 |
| 24 | Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: clinical and molecular genetic study | Lancet, The | 2004 | 538 |
| 25 | Phenotypically Concordant and Discordant Monozygotic Twins Display Different DNA Copy-Number-Variation Profiles | American Journal of Human Genetics | 2008 | 533 |
| 26 | Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data | BMJ, The | 2014 | 528 |
| 27 | An Individual Patient Data Meta-Analysis of the Long-Term Outcome of Randomised Studies Comparing Intravesical Mitomycin C versus Bacillus Calmette-Guérin for Non–Muscle-Invasive Bladder Cancer | European Urology | 2009 | 527 |
| 28 | A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX | Journal of Bone and Mineral Research | 2016 | 508 |
| 29 | 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation | Europace | 2021 | 494 |
| 30 | Identification of tissue-specific cell death using methylation patterns of circulating DNA | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 492 |
| 31 | The largest prospective warfarin-treated cohort supports genetic forecasting | Blood | 2009 | 490 |
| 32 | A three-year follow up of tension free vaginal tape for surgical treatment of female stress urinary incontinence | BJOG: an International Journal of Obstetrics and Gynaecology | 1999 | 488 |
| 33 | Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial | European Heart Journal | 2011 | 487 |
| 34 | Intravenous Immunoglobulin G Therapy in Streptococcal Toxic Shock Syndrome: A European Randomized, Double-Blind, Placebo-Controlled Trial | Clinical Infectious Diseases | 2003 | 485 |
| 35 | Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double-Blind, Placebo-Controlled Trial | Journal of the American Medical Directors Association | 2015 | 485 |
| 36 | Long-term Results of the Tension-Free Vaginal Tape (TVT) Procedure for Surgical Treatment of Female Stress Urinary Incontinence | International Urogynecology Journal | 2001 | 480 |
| 37 | Association between Oxidative Stress and Bone Mineral Density | Biochemical and Biophysical Research Communications | 2001 | 463 |
| 38 | Tumor Imaging Using a Picomolar Affinity HER2 Binding Affibody Molecule | Cancer Research | 2006 | 462 |
| 39 | A multicenter study of tension-free vaginal tape (TVT) for surgical treatment of stress urinary incontinence | International Urogynecology Journal | 1998 | 460 |
| 40 | FBXW7/hCDC4 Is a General Tumor Suppressor in Human Cancer | Cancer Research | 2007 | 458 |
| 41 | Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery | Journal of the American College of Cardiology | 2011 | 457 |
| 42 | Outcome, timing and adverse events in therapeutic hypothermia after out‐of‐hospital cardiac arrest | Acta Anaesthesiologica Scandinavica | 2009 | 445 |
| 43 | Internet-based self-help for depression: randomised controlled trial | British Journal of Psychiatry | 2005 | 431 |
| 44 | Fibroblast growth factor-23 regulates parathyroid hormone and 1α-hydroxylase expression in cultured bovine parathyroid cells | Journal of Endocrinology | 2007 | 430 |
| 45 | Managing synchronous liver metastases from colorectal cancer: A multidisciplinary international consensus | Cancer Treatment Reviews | 2015 | 430 |
| 46 | Inhaled Nitric Oxide Selectively Reverses Human Hypoxic Pulmonary Vasoconstriction without Causing Systemic Vasodilation | Anesthesiology | 1993 | 426 |
| 47 | Phylogenetic Analysis of Nitrite, Nitric Oxide, and Nitrous Oxide Respiratory Enzymes Reveal a Complex Evolutionary History for Denitrification | Molecular Biology and Evolution | 2008 | 424 |
| 48 | Correlations between RNA and protein expression profiles in 23 human cell lines | BMC Genomics | 2009 | 422 |
| 49 | EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations | Leukemia | 2012 | 409 |
| 50 | Duodenal levodopa infusion monotherapy vs oral polypharmacy in advanced Parkinson disease | Neurology | 2005 | 407 |
