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Top Articles

#TitleJournalYearCitations
1Early detection of pulmonary arterial hypertension in systemic sclerosis: A French nationwide prospective multicenter studyArthritis and Rheumatism2005656
2Prediction of Pulmonary Complications and Long‐Term Survival in Systemic SclerosisArthritis and Rheumatology2014354
3Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled studyLancet Respiratory Medicine,the2017201
4Survival in systemic sclerosis-associated pulmonary arterial hypertension in the modern management eraAnnals of the Rheumatic Diseases2013128
5Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for Digital Ulcers in Systemic Sclerosis: A Multicenter, Prospective Cohort StudyArthritis and Rheumatology2016122
6Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective studyLancet Rheumatology, The2020117
7Randomized, prospective, placebo‐controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosisArthritis and Rheumatism2010111
8Prognostic implications of serial risk score assessments in patients with pulmonary arterial hypertension: A Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) analysisJournal of Heart and Lung Transplantation2015111
9Three- Versus Two-Drug Therapy for Patients With Newly Diagnosed Pulmonary Arterial HypertensionJournal of the American College of Cardiology202190
10Treatment of patients with pulmonary arterial hypertension at the time of death or deterioration to functional class IV: Insights from the REVEAL RegistryJournal of Heart and Lung Transplantation201386
11Starving the Malaria Parasite: Inhibitors Active against the Aspartic Proteases Plasmepsins I, II, and IVAngewandte Chemie - International Edition200684
12Evaluation of Macitentan in Patients With Eisenmenger SyndromeCirculation201983
13Validation of two predictive models for survival in pulmonary arterial hypertensionEuropean Respiratory Journal201582
14Acute Heart Failure in the Elderly: Differences in Clinical Characteristics, Outcomes, and Prognostic Factors in the VERITAS StudyJournal of Cardiac Failure201565
15Impact of environmental housing conditions on the emotional responses of mice deficient for nociceptin/orphanin FQ peptide precursor geneBehavioural Brain Research200359
16Acute Hemodynamic Effects of Single‐Dose Sildenafil When Added to Established Bosentan Therapy in Patients With Pulmonary Arterial Hypertension: Results of the COMPASS‐1 StudyJournal of Clinical Pharmacology200957
17Early Worsening Heart Failure in Patients Admitted for Acute Heart Failure: Time Course, Hemodynamic Predictors, and OutcomeJournal of Cardiac Failure200956
18The glucose-lowering effects of the PDE4 inhibitors roflumilast and roflumilast-N-oxide in db/db miceDiabetologia201251
19Cardiac Troponin I and T as Prognostic Markers in Cats with Hypertrophic CardiomyopathyJournal of Veterinary Internal Medicine201443
20Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trialsLancet Infectious Diseases, The201941
21A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapyMolecular Cancer201040
22Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90Journal of Medicinal Chemistry201434
23Clinical characteristics and predictors of gangrene in patients with systemic sclerosis and digital ulcers in the Digital Ulcer Outcome Registry: a prospective, observational cohortAnnals of the Rheumatic Diseases201634
24Health State Utilities Associated with Glucose Monitoring DevicesValue in Health201728
25Effects of Miglustat on Stabilization of Neurological Disorder in Niemann–Pick Disease Type CJournal of Child Neurology201327
26A recessive ataxia diagnosis algorithm for the next generation sequencing eraAnnals of Neurology201727
27Long‐Term Outcomes in Patients With Connective Tissue Disease–Associated Pulmonary Arterial Hypertension in the Modern Treatment Era: Meta‐Analyses of Randomized, Controlled Trials and Observational RegistriesArthritis and Rheumatology202126
28A new model to evaluate the long-term cost effectiveness of orphan and highly specialised drugs following listing on the Australian Pharmaceutical Benefits Scheme: the Bosentan Patient RegistryJournal of Medical Economics200821
29Growth in children with pulmonary arterial hypertension: a longitudinal retrospective multiregistry studyLancet Respiratory Medicine,the201620
30Factors associated with disease progression in early-diagnosed pulmonary arterial hypertension associated with systemic sclerosis: longitudinal data from the DETECT cohortAnnals of the Rheumatic Diseases201820
31Risk of depression, suicide and psychosis with hydroxychloroquine treatment for rheumatoid arthritis: a multinational network cohort studyRheumatology202120
32Identification of non-peptidic neuromedin U receptor modulators by a robust homogeneous screening assayActa Pharmacologica Sinica200819
33Endothelin research and the discovery of macitentan for the treatment of pulmonary arterial hypertensionAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology201619
34Pharmacokinetic/Pharmacodynamic Modeling of Renin Biomarkers in Subjects Treated With the Renin Inhibitor AliskirenClinical Pharmacology and Therapeutics200818
35Niemann–Pick type C: focus on the adolescent/adult onset formInternational Journal of Neuroscience201618
36Prediction of Long‐Term Outcome by Measurement of Serum Concentration of Cardiac Troponins in Critically Ill Dogs with Systemic InflammationJournal of Veterinary Internal Medicine201417
37The long-term tolerability and efficacy of armodafinil in patients with excessive sleepiness associated with treated obstructive sleep apnea, shift work disorder, or narcolepsy: an open-label extension studyJournal of Clinical Sleep Medicine201017
38Vertebral fractures in Gaucher disease type I: data from the French “Observatoire” on Gaucher disease (FROG)Osteoporosis International201116
39Simultaneous pulmonary and systemic blood pressure and ECG Interval measurement in conscious, freely moving ratsJournal of the American Association for Laboratory Animal Science201215
40Endothelin Mediates the Altered Renal Hemodynamics Associated with Experimental Congestive Heart FailureJournal of Cardiovascular Pharmacology200112
41Tezosentan, a novel endothelin receptor antagonist, markedly reduces rat hepatic ischemia and reperfusion injury in three different modelsLiver Transplantation200810
42Development of macitentan for the treatment of pulmonary arterial hypertensionAnnals of the New York Academy of Sciences20157
43Risks associated with antiretroviral treatment for human immunodeficiency virus (HIV): qualitative analysis of social media data and health state utility valuationQuality of Life Research20177
44Clazosentan for patients with subarachnoid haemorrhage: lessons learned – Authors' replyLancet Neurology, The20116
45Identification of a pulmonary arterial hypertension (PAH) patient cohort and study of its burden of illness in Programme de Médicalisation des Systèmes d'information (PMSI)International Journal of Cardiology20206
46The Infiltration of Terrorist Organizations Into the Pharmaceutical Industry: Hezbollah as a Case StudyStudies in Conflict and Terrorism20135
47Pulmonary hypertension: a correct diagnosis for a suitable therapy in scleroderma patientsClinical and Experimental Rheumatology20155
48Bosentan therapy for pulmonary arterial hypertension: a case report of a 16-month-old boyCurrent Medical Research and Opinion20073
49Monocrotaline‐Induced Pulmonary Hypertension in Wistar RatsCurrent Protocols in Pharmacology20093
50The PROSPECT Registry of Pulmonary Arterial Hypertension (PAH): Description of Patients Who Transitioned From Inhaled Prostacyclin to Intravenous EpoprostenolJournal of Heart and Lung Transplantation20141