| # | Title | Journal | Year | Citations |
|---|
| 1 | The global distribution and burden of dengue | Nature | 2013 | 7,138 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | The 2021 WHO Classification of Tumors of the Central Nervous System: a summary | Neuro-Oncology | 2021 | 4,534 |
| 4 | The Somatic Genomic Landscape of Glioblastoma | Cell | 2013 | 3,979 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 6 | Colorectal cancer | Lancet, The | 2014 | 2,455 |
| 7 | Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | Nature | 2012 | 2,129 |
| 8 | eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences | Nucleic Acids Research | 2016 | 1,937 |
| 9 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 10 | Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic | Annals of Oncology | 2019 | 1,742 |
| 11 | Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors | JAMA Oncology | 2018 | 1,625 |
| 12 | Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials | Lancet Neurology, The | 2007 | 1,580 |
| 13 | Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma | Cancer Cell | 2012 | 1,551 |
| 14 | Psychosomatic Medicine in Germany: More Timely than Ever | Psychotherapy and Psychosomatics | 2016 | 1,536 |
| 15 | Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium | Clinical Infectious Diseases | 2020 | 1,429 |
| 16 | The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells | Cancer Research | 2013 | 1,413 |
| 17 | 3D printing based on imaging data: review of medical applications | International Journal of Computer Assisted Radiology and Surgery | 2010 | 1,265 |
| 18 | Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy | Nature | 2016 | 1,243 |
| 19 | Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma | New England Journal of Medicine | 2016 | 1,210 |
| 20 | Potential of fecal microbiota for early‐stage detection of colorectal cancer | Molecular Systems Biology | 2014 | 991 |
| 21 | Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium | Lancet Infectious Diseases, The | 2019 | 970 |
| 22 | Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline | Clinical Microbiology and Infection | 2018 | 942 |
| 23 | The epidemiology of skin cancer | British Journal of Dermatology | 2002 | 940 |
| 24 | Deep Learning Techniques for Automatic MRI Cardiac Multi-Structures Segmentation and Diagnosis: Is the Problem Solved? | IEEE Transactions on Medical Imaging | 2018 | 926 |
| 25 | Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay | Nature Biotechnology | 2013 | 920 |
| 26 | The future of digital health with federated learning | Npj Digital Medicine | 2020 | 887 |
| 27 | Myocardial infarction accelerates atherosclerosis | Nature | 2012 | 874 |
| 28 | 68Ga-FAPI PET/CT: Tracer Uptake in 28 Different Kinds of Cancer | Journal of Nuclear Medicine | 2019 | 874 |
| 29 | Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial | Lancet Oncology, The | 2010 | 873 |
| 30 | Lymphocyte apoptosis induced by CD95 (APO–1/Fas) ligand–expressing tumor cells — A mechanism of immune evasion? | Nature Medicine | 1996 | 872 |
| 31 | The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer | European Journal of Nuclear Medicine and Molecular Imaging | 2015 | 866 |
| 32 | Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas | Acta Neuropathologica | 2012 | 863 |
| 33 | Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group | Molecular Psychiatry | 2017 | 852 |
| 34 | Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group | Molecular Psychiatry | 2016 | 850 |
| 35 | The Role of Chest Imaging in Patient Management During the COVID-19 Pandemic | Chest | 2020 | 832 |
| 36 | EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood | Nature Reviews Clinical Oncology | 2021 | 826 |
| 37 | European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas | Lancet Oncology, The | 2017 | 816 |
| 38 | SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells | EMBO Journal | 2020 | 812 |
| 39 | K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas | Acta Neuropathologica | 2012 | 799 |
| 40 | Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Intermediate-Risk Pulmonary Embolism | Circulation | 2014 | 794 |
| 41 | Brain tumour cells interconnect to a functional and resistant network | Nature | 2015 | 787 |
| 42 | The whole-genome landscape of medulloblastoma subtypes | Nature | 2017 | 787 |
| 43 | Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY) | Stroke | 2007 | 784 |
| 44 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 45 | Dissecting the genomic complexity underlying medulloblastoma | Nature | 2012 | 765 |
| 46 | Subgroup-specific structural variation across 1,000 medulloblastoma genomes | Nature | 2012 | 761 |
| 47 | Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 755 |
| 48 | Wilson's disease and other neurological copper disorders | Lancet Neurology, The | 2015 | 751 |
| 49 | 225Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer | Journal of Nuclear Medicine | 2016 | 741 |
| 50 | Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data | Genome Medicine | 2019 | 732 |
