| # | Title | Journal | Year | Citations |
|---|
| 1 | 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2016 | 10,674 |
| 2 | The american college of rheumatology 1990 criteria for the classification of fibromyalgia | Arthritis and Rheumatism | 1990 | 7,828 |
| 3 | GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables | Journal of Clinical Epidemiology | 2011 | 6,722 |
| 4 | GRADE guidelines: 3. Rating the quality of evidence | Journal of Clinical Epidemiology | 2011 | 5,517 |
| 5 | The integrative review: updated methodology | Journal of Advanced Nursing | 2005 | 5,375 |
| 6 | Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia | New England Journal of Medicine | 2001 | 4,825 |
| 7 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 8 | Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America | Clinical Infectious Diseases | 2009 | 4,237 |
| 9 | Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II | Arthritis and Rheumatism | 2008 | 4,029 |
| 10 | The Somatic Genomic Landscape of Glioblastoma | Cell | 2013 | 3,979 |
| 11 | The consensus molecular subtypes of colorectal cancer | Nature Medicine | 2015 | 3,596 |
| 12 | Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment | Cancer Cell | 2012 | 3,578 |
| 13 | Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells | Nature Medicine | 1996 | 3,357 |
| 14 | Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients | Science | 2018 | 3,126 |
| 15 | Microbial translocation is a cause of systemic immune activation in chronic HIV infection | Nature Medicine | 2006 | 3,107 |
| 16 | The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update | Nucleic Acids Research | 2018 | 3,003 |
| 17 | Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence | Obstetrics and Gynecology | 1997 | 2,818 |
| 18 | Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice | Cell | 1997 | 2,796 |
| 19 | Decision aids for people facing health treatment or screening decisions | The Cochrane Library | 2017 | 2,780 |
| 20 | Optical properties of biological tissues: a review | Physics in Medicine and Biology | 2013 | 2,743 |
| 21 | Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome | New England Journal of Medicine | 2001 | 2,593 |
| 22 | Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations | Journal of Pain | 2008 | 2,564 |
| 23 | A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans | Diabetes | 2001 | 2,550 |
| 24 | Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America | Clinical Infectious Diseases | 2008 | 2,432 |
| 25 | Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient | Journal of Parenteral and Enteral Nutrition | 2016 | 2,390 |
| 26 | The Reactome Pathway Knowledgebase | Nucleic Acids Research | 2018 | 2,388 |
| 27 | Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis | Annals of Neurology | 1996 | 2,365 |
| 28 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 29 | Purified hematopoietic stem cells can differentiate into hepatocytes in vivo | Nature Medicine | 2000 | 2,255 |
| 30 | The origins of the developmental origins theory | Journal of Internal Medicine | 2007 | 2,167 |
| 31 | Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | New England Journal of Medicine | 2008 | 2,141 |
| 32 | Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council | Journal of Pain | 2016 | 2,040 |
| 33 | Gut hormone PYY3-36 physiologically inhibits food intake | Nature | 2002 | 2,039 |
| 34 | CD44: From adhesion molecules to signalling regulators | Nature Reviews Molecular Cell Biology | 2003 | 2,029 |
| 35 | Point Set Registration: Coherent Point Drift | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2010 | 2,018 |
| 36 | Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus | Nature | 2001 | 2,008 |
| 37 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology | Gastroenterology | 2008 | 2,002 |
| 38 | Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer | Nature | 1994 | 2,001 |
| 39 | Phosphorylated CREB binds specifically to the nuclear protein CBP | Nature | 1993 | 1,978 |
| 40 | Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine | Nature | 1991 | 1,967 |
| 41 | Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain | Journal of Pain | 2009 | 1,960 |
| 42 | Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer | Science | 2009 | 1,955 |
| 43 | Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration | Lancet, The | 1994 | 1,919 |
| 44 | Prediction of Individual Brain Maturity Using fMRI | Science | 2010 | 1,884 |
| 45 | The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism | Molecular Psychiatry | 2014 | 1,882 |
| 46 | Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome | New England Journal of Medicine | 2015 | 1,856 |
| 47 | International variation in the prevalence of COPD (The BOLD Study): a population-based prevalence study | Lancet, The | 2007 | 1,818 |
| 48 | Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor | Science | 1995 | 1,781 |
| 49 | A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis | New England Journal of Medicine | 2012 | 1,738 |
| 50 | Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer | Gastroenterology | 2012 | 1,717 |
