| # | Title | Journal | Year | Citations |
|---|
| 1 | Features and development of Coot | Acta Crystallographica Section D: Biological Crystallography | 2010 | 22,799 |
| 2 | International Physical Activity Questionnaire: 12-Country Reliability and Validity | Medicine and Science in Sports and Exercise | 2003 | 14,285 |
| 3 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement | Cytotherapy | 2006 | 13,839 |
| 4 | A New Depression Scale Designed to be Sensitive to Change | British Journal of Psychiatry | 1979 | 11,658 |
| 5 | Tissue-based map of the human proteome | Science | 2015 | 10,802 |
| 6 | Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 9,122 |
| 7 | Analysis of protein-coding genetic variation in 60,706 humans | Nature | 2016 | 9,051 |
| 8 | Inflammation, Atherosclerosis, and Coronary Artery Disease | New England Journal of Medicine | 2005 | 7,433 |
| 9 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 10 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 11 | MultiQC: summarize analysis results for multiple tools and samples in a single report | Bioinformatics | 2016 | 4,633 |
| 12 | Global prevalence of dementia: a Delphi consensus study | Lancet, The | 2005 | 4,496 |
| 13 | The nuclear RNase III Drosha initiates microRNA processing | Nature | 2003 | 4,463 |
| 14 | Cloning of a novel receptor expressed in rat prostate and ovary. | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 4,363 |
| 15 | Neuroinflammation in Alzheimer's disease | Lancet Neurology, The | 2015 | 4,129 |
| 16 | Current Concepts in Mild Cognitive Impairment | Archives of Neurology | 2001 | 4,117 |
| 17 | Mild cognitive impairment - beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment | Journal of Internal Medicine | 2004 | 4,039 |
| 18 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Nature | 2012 | 4,038 |
| 19 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 20 | HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis | Pediatric Blood and Cancer | 2007 | 4,018 |
| 21 | Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β | Endocrinology | 1997 | 4,000 |
| 22 | Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 3,827 |
| 23 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 24 | HMG-1 as a Late Mediator of Endotoxin Lethality in Mice | Science | 1999 | 3,807 |
| 25 | Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies | Lancet, The | 2010 | 3,807 |
| 26 | ILAE Official Report: A practical clinical definition of epilepsy | Epilepsia | 2014 | 3,770 |
| 27 | Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β | Endocrinology | 1998 | 3,732 |
| 28 | External review and validation of the Swedish national inpatient register | BMC Public Health | 2011 | 3,713 |
| 29 | Tumour exosome integrins determine organotropic metastasis | Nature | 2015 | 3,688 |
| 30 | Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies | Science Translational Medicine | 2014 | 3,665 |
| 31 | The global prevalence of dementia: A systematic review and metaanalysis | Alzheimer's and Dementia | 2013 | 3,654 |
| 32 | -Cell Deficit and Increased -Cell Apoptosis in Humans With Type 2 Diabetes | Diabetes | 2003 | 3,615 |
| 33 | Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland | New England Journal of Medicine | 2000 | 3,583 |
| 34 | Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys | Lancet, The | 2006 | 3,493 |
| 35 | ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology | Epilepsia | 2017 | 3,464 |
| 36 | Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain* | Acta Physiologica Scandinavica | 1971 | 3,374 |
| 37 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 38 | International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma | Lancet Oncology, The | 2014 | 3,343 |
| 39 | Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 | Nature | 1998 | 3,333 |
| 40 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 41 | Antibiotic resistance—the need for global solutions | Lancet Infectious Diseases, The | 2013 | 3,184 |
| 42 | Molecular basis of agonism and antagonism in the oestrogen receptor | Nature | 1997 | 3,139 |
| 43 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 44 | Progress and challenges in translating the biology of atherosclerosis | Nature | 2011 | 3,058 |
| 45 | Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer | New England Journal of Medicine | 2013 | 3,028 |
| 46 | The size and burden of mental disorders and other disorders of the brain in Europe 2010 | European Neuropsychopharmacology | 2011 | 2,930 |
| 47 | International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma | European Respiratory Journal | 2014 | 2,898 |
| 48 | Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma | New England Journal of Medicine | 1999 | 2,840 |
| 49 | Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics | Molecular and Cellular Proteomics | 2014 | 2,819 |
| 50 | Effects of Torcetrapib in Patients at High Risk for Coronary Events | New England Journal of Medicine | 2007 | 2,811 |
