| # | Title | Journal | Year | Citations |
|---|
| 1 | The PRISMA 2020 statement: an updated guideline for reporting systematic reviews | BMJ, The | 2021 | 26,066 |
| 2 | Preoperative assessment of liver function: a comparison of 99mTc-Mebrofenin scintigraphy with indocyanine green clearance test | Liver International | 2004 | 7,546 |
| 3 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 4 | 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative | Arthritis and Rheumatism | 2010 | 6,781 |
| 5 | Content-based image retrieval at the end of the early years | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2000 | 4,753 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 7 | Selective Search for Object Recognition | International Journal of Computer Vision | 2013 | 4,638 |
| 8 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Intensive Care Medicine | 2017 | 4,590 |
| 9 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 10 | Stress and the brain: from adaptation to disease | Nature Reviews Neuroscience | 2005 | 3,857 |
| 11 | The PRISMA 2020 statement: an updated guideline for reporting systematic reviews | Systematic Reviews | 2021 | 3,624 |
| 12 | Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19) | JAMA - Journal of the American Medical Association | 2020 | 3,597 |
| 13 | The consensus molecular subtypes of colorectal cancer | Nature Medicine | 2015 | 3,596 |
| 14 | The PRISMA 2020 statement: An updated guideline for reporting systematic reviews | International Journal of Surgery | 2021 | 3,487 |
| 15 | PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews | BMJ, The | 2021 | 3,413 |
| 16 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 17 | Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data | Neuroscience Letters | 2003 | 3,295 |
| 18 | Clonogenic assay of cells in vitro | Nature Protocols | 2006 | 3,193 |
| 19 | Duodenal Infusion of Donor Feces for RecurrentClostridium difficile | New England Journal of Medicine | 2013 | 3,157 |
| 20 | A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease | New England Journal of Medicine | 1997 | 3,152 |
| 21 | Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease | New England Journal of Medicine | 2005 | 3,152 |
| 22 | Factoring polynomials with rational coefficients | Mathematische Annalen | 1982 | 3,147 |
| 23 | Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria | Nature | 1994 | 3,138 |
| 24 | An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias | American Journal of Respiratory and Critical Care Medicine | 2013 | 3,134 |
| 25 | XLI. On the change of form of long waves advancing in a rectangular canal, and on a new type of long stationary waves | The London, Edinburgh and Dublin Philosophical Magazine and Journal of Science | 1895 | 3,119 |
| 26 | A two-solar-mass neutron star measured using Shapiro delay | Nature | 2010 | 3,065 |
| 27 | The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews | BMC Medical Research Methodology | 2003 | 3,036 |
| 28 | 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2010 | 2,994 |
| 29 | Heart rate variability: Origins, methods, and interpretive caveats | Psychophysiology | 1997 | 2,945 |
| 30 | Effects of Torcetrapib in Patients at High Risk for Coronary Events | New England Journal of Medicine | 2007 | 2,811 |
| 31 | Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest | New England Journal of Medicine | 2013 | 2,805 |
| 32 | The multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue | Journal of Psychosomatic Research | 1995 | 2,768 |
| 33 | Significance of Inducible Defense-related Proteins in Infected Plants | Annual Review of Phytopathology | 2006 | 2,754 |
| 34 | Histone deacetylases (HDACs): characterization of the classical HDAC family | Biochemical Journal | 2003 | 2,671 |
| 35 | The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After | Surgery | 2017 | 2,655 |
| 36 | Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data | Nucleic Acids Research | 2009 | 2,568 |
| 37 | Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins | Integrated Environmental Assessment and Management | 2011 | 2,567 |
| 38 | The Role of the Medial Frontal Cortex in Cognitive Control | Science | 2004 | 2,562 |
| 39 | Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews | Journal of Clinical Epidemiology | 2005 | 2,557 |
| 40 | ESMO consensus guidelines for the management of patients with metastatic colorectal cancer | Annals of Oncology | 2016 | 2,545 |
| 41 | The polycomb group protein EZH2 is involved in progression of prostate cancer | Nature | 2002 | 2,411 |
| 42 | The global k-means clustering algorithm | Pattern Recognition | 2003 | 2,401 |
| 43 | Prevalence of Age-Related Macular Degeneration in the United States | JAMA Ophthalmology | 2004 | 2,397 |
| 44 | Transition-metal-based magnetic refrigerants for room-temperature applications | Nature | 2002 | 2,394 |
| 45 | MAGMA: Generalized Gene-Set Analysis of GWAS Data | PLoS Computational Biology | 2015 | 2,344 |
| 46 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Critical Care Medicine | 2017 | 2,336 |
| 47 | Principles of Critical Discourse Analysis | Discourse and Society | 1993 | 2,327 |
| 48 | Delayed gastric emptying (DGE) after pancreatic surgery: A suggested definition by the International Study Group of Pancreatic Surgery (ISGPS) | Surgery | 2007 | 2,293 |
| 49 | Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica | Science | 2008 | 2,289 |
| 50 | Polycomb complexes repress developmental regulators in murine embryonic stem cells | Nature | 2006 | 2,273 |
