Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk | Nature | 2011 | 1.6K |
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry | Nature Protocols | 2011 | 1.5K |
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis | Cell | 2011 | 1.4K |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1.4K |
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia | Nature | 2011 | 1.1K |
Principles of early drug discovery | British Journal of Pharmacology | 2011 | 1.1K |
Impact of high-throughput screening in biomedical research | Nature Reviews Drug Discovery | 2011 | 768 |
Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry | Green Chemistry | 2011 | 725 |
Case definition and phenotype standardization in drug-induced liver injury | Clinical Pharmacology and Therapeutics | 2011 | 563 |
American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials | Arthritis and Rheumatism | 2011 | 520 |
Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes | Organic Process Research and Development | 2011 | 456 |
GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition | Clinical Cancer Research | 2011 | 442 |
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma | Nature Genetics | 2011 | 415 |
Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: Aids Clinical Trials Group A5224s, a substudy of ACTG A5202 | Journal of Infectious Diseases | 2011 | 386 |
DTI measures in crossing-fibre areas: increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease | NeuroImage | 2011 | 381 |
Managing the challenge of chemically reactive metabolites in drug development | Nature Reviews Drug Discovery | 2011 | 348 |
Basic statistical analysis in genetic case-control studies | Nature Protocols | 2011 | 344 |
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure | Nature Genetics | 2011 | 338 |
Epidemiology and etiology of denture stomatitis | Journal of Prosthodontics | 2011 | 333 |
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis | Journal of Immunology | 2011 | 315 |
Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy | NeuroImage | 2011 | 308 |
Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers | Organic Process Research and Development | 2011 | 308 |
In Vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor | Antimicrobial Agents and Chemotherapy | 2011 | 304 |
Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation | American Journal of Respiratory and Critical Care Medicine | 2011 | 283 |
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis | Cancer Cell | 2011 | 282 |