| The genome sequence of Drosophila melanogaster | Science | 2000 | 4.9K |
| The diversity-stability debate | Nature | 2000 | 1.9K |
| Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix | Journal of Clinical Oncology | 2000 | 1.7K |
| Voice-selective areas in human auditory cortex | Nature | 2000 | 1.4K |
| Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome | Nature Cell Biology | 2000 | 1.2K |
| A mesoscale phytoplankton bloom in the polar Southern Ocean stimulated by iron fertilization | Nature | 2000 | 1.2K |
| Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05 | International Journal of Radiation Oncology Biology Physics | 2000 | 1.2K |
| Maternal care, hippocampal synaptogenesis and cognitive development in rats | Nature Neuroscience | 2000 | 968 |
| Use of oral corticosteroids and risk of fractures | Journal of Bone and Mineral Research | 2000 | 931 |
| Physicians and the pharmaceutical industry: is a gift ever just a gift? | JAMA - Journal of the American Medical Association | 2000 | 831 |
| A Noncooperative Model of Network Formation | Econometrica | 2000 | 775 |
| Importance of replication in microarray gene expression studies: statistical methods and evidence from repetitive cDNA hybridizations | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 703 |
| Growth patterns in the developing brain detected by using continuum mechanical tensor maps | Nature | 2000 | 690 |
| Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus | Nature Medicine | 2000 | 639 |
| Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping | Analytical Chemistry | 2000 | 564 |
| Mechanisms of sodium pump regulation | American Journal of Physiology - Cell Physiology | 2000 | 562 |
| Socio-economic disparities in pregnancy outcome: why do the poor fare so poorly? | Paediatric and Perinatal Epidemiology | 2000 | 554 |
| Volumetry of hippocampus and amygdala with high-resolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories | Cerebral Cortex | 2000 | 553 |
| Oral corticosteroids and fracture risk: relationship to daily and cumulative doses | Rheumatology | 2000 | 491 |
| Variations in maternal care in infancy regulate the development of stress reactivity | Biological Psychiatry | 2000 | 475 |
| Social support, depression, and mortality during the first year after myocardial infarction | Circulation | 2000 | 468 |
| Missing Surface Inflection or Impairment in second language acquisition? Evidence from tense and agreement | Second Language Research | 2000 | 450 |
| The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat | Neuropsychopharmacology | 2000 | 449 |
| Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial. The Altered Peptide Ligand in Relapsing MS Study Group | Nature Medicine | 2000 | 446 |
| Arctic and boreal ecosystems of western North America as components of the climate system. | Global Change Biology | 2000 | 431 |
