| # | Title | Journal | Year | Citations |
|---|
| 1 | RoB 2: a revised tool for assessing risk of bias in randomised trials | BMJ: British Medical Journal | 2019 | 10,984 |
| 2 | The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons | Journal of the American Geriatrics Society | 1991 | 10,854 |
| 3 | Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging | Journal of the American Society of Echocardiography | 2015 | 10,755 |
| 4 | ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions | BMJ, The | 2016 | 8,654 |
| 5 | A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff | Fly | 2012 | 8,643 |
| 6 | Statistical parametric maps in functional imaging: A general linear approach | Human Brain Mapping | 1994 | 8,177 |
| 7 | The Clavien-Dindo Classification of Surgical Complications | Annals of Surgery | 2009 | 8,080 |
| 8 | Planetary boundaries: Guiding human development on a changing planet | Science | 2015 | 7,124 |
| 9 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 10 | Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Nature | 1993 | 6,331 |
| 11 | Modification of seizure activity by electrical stimulation: II. Motor seizure | Electroencephalography and Clinical Neurophysiology | 1972 | 6,152 |
| 12 | Solutions for a cultivated planet | Nature | 2011 | 5,821 |
| 13 | A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 | Science | 1994 | 5,747 |
| 14 | Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography | Journal of the American Society of Echocardiography | 2010 | 5,724 |
| 15 | The McGill Pain Questionnaire: Major properties and scoring methods | Pain | 1975 | 5,648 |
| 16 | The Genome Sequence of Drosophila melanogaster | Science | 2000 | 5,566 |
| 17 | Epigenetic programming by maternal behavior | Nature Neuroscience | 2004 | 5,564 |
| 18 | A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase | Nature Genetics | 1995 | 5,180 |
| 19 | Biodiversity loss and its impact on humanity | Nature | 2012 | 4,969 |
| 20 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 21 | Brain development during childhood and adolescence: a longitudinal MRI study | Nature Neuroscience | 1999 | 4,670 |
| 22 | Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer | New England Journal of Medicine | 2005 | 4,601 |
| 23 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Nature Reviews Genetics | 2008 | 4,577 |
| 24 | A nonparametric method for automatic correction of intensity nonuniformity in MRI data | IEEE Transactions on Medical Imaging | 1998 | 4,181 |
| 25 | Neuroinflammation in Alzheimer's disease | Lancet Neurology, The | 2015 | 4,129 |
| 26 | The metacommunity concept: a framework for multi-scale community ecology | Ecology Letters | 2004 | 4,069 |
| 27 | The Correlates of Entrepreneurship in Three Types of Firms | Management Science | 1983 | 3,975 |
| 28 | Functional profiling of the Saccharomyces cerevisiae genome | Nature | 2002 | 3,938 |
| 29 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 30 | Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis | Science | 1999 | 3,761 |
| 31 | Antithrombotic Therapy for VTE Disease | Chest | 2012 | 3,745 |
| 32 | The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) | IEEE Transactions on Medical Imaging | 2015 | 3,589 |
| 33 | LSQR: An Algorithm for Sparse Linear Equations and Sparse Least Squares | ACM Transactions on Mathematical Software | 1982 | 3,556 |
| 34 | Nanocelluloses: A New Family of Nature‐Based Materials | Angewandte Chemie - International Edition | 2011 | 3,550 |
| 35 | Life with 6000 Genes | Science | 1996 | 3,548 |
| 36 | Rebuilding community ecology from functional traits | Trends in Ecology and Evolution | 2006 | 3,525 |
| 37 | The short-form McGill pain questionnaire | Pain | 1987 | 3,518 |
| 38 | Oscillation and chaos in physiological control systems | Science | 1977 | 3,516 |
| 39 | Polymer Vesicles | Science | 2002 | 3,444 |
| 40 | Triple-Negative Breast Cancer | New England Journal of Medicine | 2010 | 3,233 |
| 41 | Identification of the breast cancer susceptibility gene BRCA2 | Nature | 1995 | 3,230 |
| 42 | MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis | Nucleic Acids Research | 2018 | 3,199 |
| 43 | Crizotinib versus Chemotherapy in AdvancedALK-Positive Lung Cancer | New England Journal of Medicine | 2013 | 3,181 |
| 44 | Of strategies, deliberate and emergent | Strategic Management Journal | 1985 | 3,128 |
| 45 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 46 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit | Critical Care Medicine | 2013 | 3,066 |
| 47 | Automatic 3D Intersubject Registration of MR Volumetric Data in Standardized Talairach Space | Journal of Computer Assisted Tomography | 1994 | 3,049 |
| 48 | Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse | Nature Neuroscience | 2009 | 3,035 |
| 49 | 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2010 | 2,994 |
| 50 | Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change | Psychoneuroendocrinology | 2003 | 2,979 |
