| # | Title | Journal | Year | Citations |
|---|
|
| 1 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,596 |
| 2 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 7,596 |
| 3 | Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 7,201 |
| 4 | The mutational constraint spectrum quantified from variation in 141,456 humans | Nature | 2020 | 6,794 |
| 5 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,546 |
| 6 | Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 | Journal of the American College of Cardiology | 2020 | 5,418 |
| 7 | The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines | International Journal of Surgery | 2020 | 5,114 |
| 8 | Emerging applications of stimuli-responsive polymer materials | Nature Materials | 2010 | 5,088 |
| 9 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 10 | The socio-economic implications of the coronavirus pandemic (COVID-19): A review | International Journal of Surgery | 2020 | 4,574 |
| 11 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,451 |
| 12 | World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19) | International Journal of Surgery | 2020 | 4,142 |
| 13 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,992 |
| 14 | TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells | Nature | 2018 | 3,649 |
| 15 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,300 |
| 16 | Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer | New England Journal of Medicine | 2018 | 3,282 |
| 17 | Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial | Lancet, The | 2016 | 3,166 |
| 18 | Estimates of the severity of coronavirus disease 2019: a model-based analysis | Lancet Infectious Diseases, The | 2020 | 3,152 |
| 19 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,742 |
| 20 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,676 |
| 21 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research | PLoS Biology | 2020 | 2,646 |
| 22 | Application of fuzzy algorithms for control of simple dynamic plant | Proceedings of the Institution of Electrical Engineers | 1974 | 2,641 |
| 23 | CYCLOOXYGENASES 1 AND 2 | Annual Review of Pharmacology and Toxicology | 1998 | 2,596 |
| 24 | The structure and dynamics of multilayer networks | Physics Reports | 2014 | 2,578 |
| 25 | Learning to Compare: Relation Network for Few-Shot Learning | | 2018 | 2,555 |
| 26 | Chronic inflammation in the etiology of disease across the life span | Nature Medicine | 2019 | 2,537 |
| 27 | Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems | Nanoscale | 2015 | 2,517 |
| 28 | EAU Guidelines on Renal Cell Carcinoma: 2014 Update | European Urology | 2015 | 2,498 |
| 29 | A flat Universe from high-resolution maps of the cosmic microwave background radiation | Nature | 2000 | 2,258 |
| 30 | Fibroblast growth factor signalling: from development to cancer | Nature Reviews Cancer | 2010 | 2,243 |
| 31 | Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies | BMJ: British Medical Journal | 2009 | 2,202 |
| 32 | A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease | Nature Genetics | 2015 | 2,178 |
| 33 | MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer | Nature | 2014 | 2,151 |
| 34 | Lignocellulosic biomass: a sustainable platform for the production of bio-based chemicals and polymers | Polymer Chemistry | 2015 | 2,047 |
| 35 | Raman Spectroscopy of Biological Tissues | Applied Spectroscopy Reviews | 2007 | 2,011 |
| 36 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,992 |
| 37 | The UKIRT Infrared Deep Sky Survey (UKIDSS) | Monthly Notices of the Royal Astronomical Society | 2007 | 1,986 |
| 38 | 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk | Atherosclerosis | 2019 | 1,953 |
| 39 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,855 |
| 40 | Hybridization and speciation | Journal of Evolutionary Biology | 2013 | 1,819 |
| 41 | Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial | Lancet, The | 2017 | 1,819 |
| 42 | Cellular Senescence: Defining a Path Forward | Cell | 2019 | 1,795 |
| 43 | Pembrolizumab for Early Triple-Negative Breast Cancer | New England Journal of Medicine | 2020 | 1,764 |
| 44 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,724 |
| 45 | Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis | Nature Genetics | 2010 | 1,658 |
| 46 | Mortality after surgery in Europe: a 7 day cohort study | Lancet, The | 2012 | 1,642 |
| 47 | Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease | Biochimica Et Biophysica Acta - Molecular Cell Research | 2014 | 1,615 |
| 48 | Global Burden of Severe Periodontitis in 1990-2010 | Journal of Dental Research | 2014 | 1,613 |
| 49 | Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies | Lancet Neurology, The | 2019 | 1,596 |
| 50 | Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis | BMJ, The | 2020 | 1,581 |
