| # | Title | Journal | Year | Citations |
|---|
| 1 | Sarcopenia: revised European consensus on definition and diagnosis | Age and Ageing | 2019 | 6,824 |
| 2 | Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus | Arthritis and Rheumatism | 2012 | 3,838 |
| 3 | Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial | Lancet, The | 2010 | 2,857 |
| 4 | Clinical diagnostic criteria for dementia associated with Parkinson's disease | Movement Disorders | 2007 | 2,497 |
| 5 | 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | Arthritis and Rheumatism | 2013 | 2,359 |
| 6 | European Guidelines for Obesity Management in Adults | Obesity Facts | 2015 | 2,172 |
| 7 | Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis | New England Journal of Medicine | 2018 | 1,944 |
| 8 | Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines | Movement Disorders | 2012 | 1,908 |
| 9 | Novel Total Antioxidant Capacity Index for Dietary Polyphenols and Vitamins C and E, Using Their Cupric Ion Reducing Capability in the Presence of Neocuproine: CUPRAC Method | Journal of Agricultural and Food Chemistry | 2004 | 1,840 |
| 10 | Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions | Cell | 2015 | 1,725 |
| 11 | 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2013 | 1,705 |
| 12 | Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2) | Cell | 2000 | 1,489 |
| 13 | The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission1 | Epilepsia | 2011 | 1,454 |
| 14 | Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A | Nature Genetics | 2004 | 1,391 |
| 15 | Acid Mine Drainage (AMD): causes, treatment and case studies | Journal of Cleaner Production | 2006 | 1,157 |
| 16 | Rivastigmine for Dementia Associated with Parkinson's Disease | New England Journal of Medicine | 2004 | 1,111 |
| 17 | A Calcium Antagonist vs a Non–Calcium Antagonist Hypertension Treatment Strategy for Patients With Coronary Artery Disease | JAMA - Journal of the American Medical Association | 2003 | 1,107 |
| 18 | Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial | Lancet, The | 2005 | 1,105 |
| 19 | EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria | Annals of the Rheumatic Diseases | 2010 | 1,073 |
| 20 | Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial | Lancet, The | 2018 | 984 |
| 21 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 22 | Mutations in Kir2.1 Cause the Developmental and Episodic Electrical Phenotypes of Andersen's Syndrome | Cell | 2001 | 921 |
| 23 | 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents | Journal of Hypertension | 2016 | 898 |
| 24 | EULAR recommendations for the management of primary small and medium vessel vasculitis | Annals of the Rheumatic Diseases | 2009 | 889 |
| 25 | Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force | Movement Disorders | 2007 | 885 |
| 26 | Immunosuppressive therapy in lupus nephritis: The Euro‐Lupus Nephritis Trial, a randomized trial of low‐dose versus high‐dose intravenous cyclophosphamide | Arthritis and Rheumatism | 2002 | 849 |
| 27 | Pyogenic Bacterial Infections in Humans with MyD88 Deficiency | Science | 2008 | 844 |
| 28 | International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods | Epilepsia | 2013 | 816 |
| 29 | Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III | Nature Genetics | 1997 | 812 |
| 30 | Strict Blood-Pressure Control and Progression of Renal Failure in Children | New England Journal of Medicine | 2009 | 798 |
| 31 | International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology | Lancet, The | 2015 | 780 |
| 32 | Comparative Evaluation of Various Total Antioxidant Capacity Assays Applied to Phenolic Compounds with the CUPRAC Assay | Molecules | 2007 | 764 |
| 33 | Clinical patterns of neurological involvement in Behçet's disease: evaluation of 200 patients | Brain | 1999 | 760 |
| 34 | Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone) | Pain Practice | 2008 | 710 |
| 35 | Identifying Autism Loci and Genes by Tracing Recent Shared Ancestry | Science | 2008 | 688 |
| 36 | The genomic basis of trophic strategy in marine bacteria | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 685 |
| 37 | Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey | Lancet, The | 2021 | 683 |
| 38 | Mutations in the O-Mannosyltransferase Gene POMT1 Give Rise to the Severe Neuronal Migration Disorder Walker-Warburg Syndrome | American Journal of Human Genetics | 2002 | 636 |
| 39 | The Long-Term Mortality and Morbidity of Behçet Syndrome | Medicine (United States) | 2003 | 635 |
| 40 | A Controlled Trial of Azathioprine in Behçet's Syndrome | New England Journal of Medicine | 1990 | 634 |
| 41 | Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness | Nature Genetics | 1999 | 633 |
| 42 | EULAR recommendations for the management of Behcet disease | Annals of the Rheumatic Diseases | 2008 | 624 |
| 43 | Association of Cardiometabolic Multimorbidity With Mortality | JAMA - Journal of the American Medical Association | 2015 | 624 |
| 44 | Clinical and Molecular Genetic Spectrum of Congenital Deficiency of the Leptin Receptor | New England Journal of Medicine | 2007 | 610 |
| 45 | TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis | Science Translational Medicine | 2014 | 600 |
| 46 | EULAR recommendations for the management of large vessel vasculitis | Annals of the Rheumatic Diseases | 2009 | 596 |
| 47 | Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease | Nature Genetics | 2010 | 595 |
| 48 | A review: Current analytical methods for the determination of biogenic amines in foods | Food Chemistry | 2007 | 592 |
| 49 | Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis | New England Journal of Medicine | 2012 | 588 |
| 50 | Connexin 43 (GJA1) Mutations Cause the Pleiotropic Phenotype of Oculodentodigital Dysplasia | American Journal of Human Genetics | 2003 | 585 |
