| # | Title | Journal | Year | Citations |
|---|
| 1 | Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease? | Hypertension | 2003 | 1,121 |
| 2 | Simultaneous Emergence of Multidrug-ResistantCandida aurison 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses | Clinical Infectious Diseases | 2017 | 1,099 |
| 3 | Trinucleotide repeat length instability and age of onset in Huntington's disease | Nature Genetics | 1993 | 1,008 |
| 4 | Ensemble of surrogates | Structural and Multidisciplinary Optimization | 2007 | 544 |
| 5 | A reliable index for the prognostic significance of blood pressure variability | Journal of Hypertension | 2005 | 387 |
| 6 | Mechanisms of Disease: oxidative stress and inflammation in the pathogenesis of hypertension | Nature Clinical Practice Nephrology | 2006 | 350 |
| 7 | First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia | Journal of Infection | 2016 | 340 |
| 8 | Resilience in natural and socioeconomic systems | Environment and Development Economics | 1998 | 272 |
| 9 | Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes | JAMA - Journal of the American Medical Association | 2019 | 265 |
| 10 | An optimization methodology of alkaline–surfactant–polymer flooding processes using field scale numerical simulation and multiple surrogates | Journal of Petroleum Science and Engineering | 2005 | 262 |
| 11 | Essential Hypertension, Progressive Renal Disease, and Uric Acid: A Pathogenetic Link?: Table 1. | Journal of the American Society of Nephrology: JASN | 2005 | 259 |
| 12 | Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia | American Journal of Physiology - Renal Physiology | 2008 | 254 |
| 13 | Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth | International Journal of Reproductive Medicine | 2014 | 247 |
| 14 | Response surface approximation of Pareto optimal front in multi-objective optimization | Computer Methods in Applied Mechanics and Engineering | 2007 | 234 |
| 15 | Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all | American Journal of Physiology - Renal Physiology | 2004 | 229 |
| 16 | Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses | MBio | 2020 | 224 |
| 17 | Reduction of renal immune cell infiltration results in blood pressure control in genetically hypertensive rats | American Journal of Physiology - Renal Physiology | 2002 | 219 |
| 18 | Huntington's disease in venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals | Movement Disorders | 1990 | 216 |
| 19 | Development of a Panel of Genome-Wide Ancestry Informative Markers to Study Admixture Throughout the Americas | PLoS Genetics | 2012 | 212 |
| 20 | Huntington's disease gene: Regional and cellular expression in brain of normal and affected individuals | Annals of Neurology | 1995 | 206 |
| 21 | Mycophenolate Mofetil Treatment Improves Hypertension in Patients with Psoriasis and Rheumatoid Arthritis | Journal of the American Society of Nephrology: JASN | 2006 | 199 |
| 22 | Effect of oat’s soluble fibre (β-glucan) as a fat replacer on physical, chemical, microbiological and sensory properties of low-fat beef patties | Meat Science | 2008 | 175 |
| 23 | Long-lasting delayed hyperalgesia after subchronic swim stress | Pharmacology Biochemistry and Behavior | 2000 | 167 |
| 24 | Antioxidant-Rich Diet Relieves Hypertension and Reduces Renal Immune Infiltration in Spontaneously Hypertensive Rats | Hypertension | 2003 | 167 |
| 25 | Optical functions of chalcopyrite CuGa x In 1-x Se 2 alloys | Applied Physics A: Materials Science and Processing | 2002 | 160 |
| 26 | A preliminary evaluation of turbidity removal by natural coagulants indigenous to Venezuela | Process Biochemistry | 1999 | 139 |
| 27 | Effect of pure and mixed cultures of the main wine yeast species on grape must fermentations | European Food Research and Technology | 2010 | 135 |
| 28 | Mutation rates at Y chromosome specific microsatellites | Human Mutation | 2005 | 133 |
| 29 | Early and Sustained Inhibition of Nuclear Factor-κB Prevents Hypertension in Spontaneously Hypertensive Rats | Journal of Pharmacology and Experimental Therapeutics | 2005 | 133 |
| 30 | 24‐Hour Blood Pressure Variability Assessed by Average Real Variability: A Systematic Review and Meta‐Analysis | Journal of the American Heart Association | 2017 | 133 |
| 31 | A global reptile assessment highlights shared conservation needs of tetrapods | Nature | 2022 | 130 |
| 32 | Cytotoxicity and mode of action of maleic hydrazide in root tips of Allium cepa L. | Environmental Research | 2004 | 128 |
| 33 | Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society? | Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology | 2009 | 117 |
| 34 | Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy | Journal of Diabetes Research | 2018 | 117 |
| 35 | Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats | American Journal of Physiology - Renal Physiology | 2003 | 115 |
| 36 | Regression analyses and motile sperm subpopulation structure study as improving tools in boar semen quality analysis | Theriogenology | 2004 | 112 |
| 37 | Evolution of Renal Interstitial Inflammation and NF-κB Activation in Spontaneously Hypertensive Rats | American Journal of Nephrology | 2004 | 107 |
| 38 | TAXONOMIC STATUS OF THE GENUS SOTALIA: SPECIES LEVEL RANKING FOR "TUCUXI" (SOTALIA FLUVIATILIS) AND "COSTERO" (SOTALIA GUIANENSIS) DOLPHINS | Marine Mammal Science | 2007 | 107 |
| 39 | Steel cathodic protection afforded by zinc, aluminium and zinc/aluminium alloy coatings in the atmosphere | Surface and Coatings Technology | 2005 | 104 |
| 40 | Velocity field across the Southern Caribbean Plate Boundary and estimates of Caribbean/South-American Plate Motion using GPS Geodesy 1994-2000 | Geophysical Research Letters | 2001 | 103 |
| 41 | Characterization of honey produced in Venezuela | Food Chemistry | 2004 | 103 |
| 42 | Structural and Ultrastructural Analysis of Cerebral Cortex, Cerebellum, and Hypothalamus from Diabetic Rats | Experimental Diabetes Research | 2009 | 102 |
| 43 | Effect of mixed culture fermentations on yeast populations and aroma profile | LWT - Food Science and Technology | 2012 | 101 |
| 44 | Comparative spectroscopic characterization of different pectins and their sources | Food Hydrocolloids | 1998 | 100 |
| 45 | Substance P and calcitonin gene-related peptide increase IL-1β, IL-6 and TNFα secretion from human peripheral blood mononuclear cells | Neurochemistry International | 2002 | 100 |
| 46 | Association of mitochondrial SOD deficiency with salt-sensitive hypertension and accelerated renal senescence | Journal of Applied Physiology | 2007 | 100 |
| 47 | Major Cardiovascular Risk Factors in Latin America: A Comparison with the United States. The Latin American Consortium of Studies in Obesity (LASO) | PLoS ONE | 2013 | 100 |
| 48 | Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin | Experimental Gerontology | 2002 | 98 |
| 49 | Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna | South American Journal of Herpetology | 2019 | 98 |
| 50 | Overload proteinuria is followed by salt-sensitive hypertension caused by renal infiltration of immune cells | American Journal of Physiology - Renal Physiology | 2002 | 96 |
