| # | Title | Journal | Year | Citations |
|---|
| 1 | EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016 | European Urology | 2017 | 1,594 |
| 2 | Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial | Lancet Oncology, The | 2014 | 1,280 |
| 3 | Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis | New England Journal of Medicine | 2000 | 1,181 |
| 4 | Balloon Angioplasty versus Implantation of Nitinol Stents in the Superficial Femoral Artery | New England Journal of Medicine | 2006 | 1,091 |
| 5 | EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013 | European Urology | 2013 | 1,053 |
| 6 | Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c | Nature | 1998 | 828 |
| 7 | Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial | Lancet, The | 2005 | 828 |
| 8 | European Association of Urology Guidelines on Upper Urinary Tract Urothelial Cell Carcinoma: 2015 Update | European Urology | 2015 | 804 |
| 9 | MULTICENTER RANDOMIZED TRIAL COMPARING TACROLIMUS (FK506) AND CYCLOSPORINE IN THE PREVENTION OF RENAL ALLOGRAFT REJECTION1 | Transplantation | 1997 | 652 |
| 10 | European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2017 Update | European Urology | 2018 | 627 |
| 11 | Long-term outcome in congenitally corrected transposition of the great arteries | Journal of the American College of Cardiology | 2000 | 616 |
| 12 | Chemosensitisation of malignant melanoma by BCL2 antisense therapy | Lancet, The | 2000 | 501 |
| 13 | Arterial Puncture Closing Devices Compared With Standard Manual Compression After Cardiac Catheterization | JAMA - Journal of the American Medical Association | 2004 | 493 |
| 14 | T(14;18)(q32;q21) involving IGH andMALT1 is a frequent chromosomal aberration in MALT lymphoma | Blood | 2003 | 480 |
| 15 | Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus ‘conventional’ protective ventilation (6 ml/kg) in severe ARDS | Intensive Care Medicine | 2013 | 474 |
| 16 | The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT) | Clinical and Experimental Allergy | 1999 | 456 |
| 17 | European position statement on lung cancer screening | Lancet Oncology, The | 2017 | 428 |
| 18 | Natural History of Very Severe Aortic Stenosis | Circulation | 2010 | 424 |
| 19 | SIROLIMUS ALLOWS EARLY CYCLOSPORINE WITHDRAWAL IN RENAL TRANSPLANTATION RESULTING IN IMPROVED RENAL FUNCTION AND LOWER BLOOD PRESSURE1,2,10 | Transplantation | 2001 | 399 |
| 20 | Statins but Not Angiotensin-Converting Enzyme Inhibitors Delay Progression of Aortic Stenosis | Circulation | 2004 | 391 |
| 21 | Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites | Leukemia | 2004 | 385 |
| 22 | Mild and moderate aortic stenosis Natural history and risk stratification by echocardiography | European Heart Journal | 2004 | 383 |
| 23 | Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA | Annals of the Rheumatic Diseases | 2010 | 376 |
| 24 | Risk factors and basic mechanisms of chronic thromboembolic pulmonary hypertension: a current understanding | European Respiratory Journal | 2013 | 361 |
| 25 | The role of heme oxygenase-1 promoter polymorphisms in human disease | Free Radical Biology and Medicine | 2004 | 356 |
| 26 | T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma | Leukemia | 2005 | 354 |
| 27 | Advanced Glycation End Product-Induced Activation of NF-κB is Suppressed by α-Lipoic Acid in Cultured Endothelial Cells | Diabetes | 1997 | 349 |
| 28 | Vaccination with genetically engineered allergens prevents progression of allergic disease | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 340 |
| 29 | Nonselective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients With Cirrhosis and Spontaneous Bacterial Peritonitis | Gastroenterology | 2014 | 336 |
| 30 | Diastolic Pulmonary Vascular Pressure Gradient | Chest | 2013 | 334 |
| 31 | Obesity Decreases Perioperative Tissue Oxygenation | Anesthesiology | 2004 | 328 |
| 32 | Guidelines for the management of vitiligo: the European Dermatology Forum consensus | British Journal of Dermatology | 2013 | 328 |
| 33 | Extended Adjuvant Therapy With Anastrozole Among Postmenopausal Breast Cancer Patients: Results From the Randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a | Journal of the National Cancer Institute | 2007 | 288 |
| 34 | “overestimation” of catheter gradients by doppler ultrasound in patients with aortic stenosis: a predictable manifestation of pressure recovery | Journal of the American College of Cardiology | 1999 | 273 |
| 35 | Randomized Adjuvant Trial of Tamoxifen and Goserelin Versus Cyclophosphamide, Methotrexate, and Fluorouracil: Evidence for the Superiority of Treatment With Endocrine Blockade in Premenopausal Patients With Hormone-Responsive Breast Cancer—Austrian Breast and Colorectal Cancer Study Group Trial 5 | Journal of Clinical Oncology | 2002 | 271 |
| 36 | SERUM COBALT LEVELS AFTER METAL-ON-METAL TOTAL HIP ARTHROPLASTY | Journal of Bone and Joint Surgery - Series A | 2003 | 261 |
| 37 | Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism | Journal of the American College of Cardiology | 2017 | 258 |
| 38 | Incidence and prognosis of early hepatic dysfunction in critically ill patients—A prospective multicenter study | Critical Care Medicine | 2007 | 250 |
| 39 | Autoimmune Bullous Skin Disorders with Immune Checkpoint Inhibitors Targeting PD-1 and PD-L1 | Cancer Immunology Research | 2016 | 247 |
| 40 | Antioxidant status in patients with acute respiratory distress syndrome | Intensive Care Medicine | 1999 | 245 |
| 41 | Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies | Clinical and Experimental Allergy | 2003 | 244 |
| 42 | Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak | Annals of Intensive Care | 2020 | 239 |
| 43 | Treatment-by-Histology Interaction Analyses in Three Phase III Trials Show Superiority of Pemetrexed in Nonsquamous Non-small Cell Lung Cancer | Journal of Thoracic Oncology | 2011 | 236 |
| 44 | Circulating Breast Cancer Cells Are Frequently Apoptotic | American Journal of Pathology | 2001 | 232 |
| 45 | Recombinant Carp Parvalbumin, the Major Cross-Reactive Fish Allergen: A Tool for Diagnosis and Therapy of Fish Allergy | Journal of Immunology | 2002 | 223 |
| 46 | A Systematic Review and Meta-analysis of Clinicopathologic Factors Linked to Intravesical Recurrence After Radical Nephroureterectomy to Treat Upper Tract Urothelial Carcinoma | European Urology | 2015 | 218 |
| 47 | Prostate Cancer: Accurate Determination of Extracapsular Extension with High-Spatial-Resolution Dynamic Contrast-enhanced and T2-weighted MR Imaging—Initial Results | Radiology | 2007 | 217 |
| 48 | Pulmonary Hypertension in Heart Failure. Epidemiology, Right Ventricular Function, and Survival | American Journal of Respiratory and Critical Care Medicine | 2015 | 217 |
| 49 | Oncologic Outcomes of Kidney-sparing Surgery Versus Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the EAU Non-muscle Invasive Bladder Cancer Guidelines Panel | European Urology | 2016 | 215 |
| 50 | Transabdominal bowel sonography for the detection of intestinal complications in Crohn’s disease | Gut | 1999 | 212 |
