| # | Title | Journal | Year | Citations |
|---|
| 1 | Effects of Torcetrapib in Patients at High Risk for Coronary Events | New England Journal of Medicine | 2007 | 2,811 |
| 2 | Listening to silence and understanding nonsense: exonic mutations that affect splicing | Nature Reviews Genetics | 2002 | 1,923 |
| 3 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation | Heart Rhythm | 2017 | 1,671 |
| 4 | Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting. | Journal of Clinical Oncology | 1989 | 1,466 |
| 5 | Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells | New England Journal of Medicine | 2004 | 1,293 |
| 6 | Iodination of proteins, glycoproteins, and peptides using a solid-phase oxidizing agent, 1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril (Iodogen) | Analytical Biochemistry | 1981 | 1,198 |
| 7 | Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors | European Journal of Endocrinology | 2016 | 1,173 |
| 8 | Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial | Lancet, The | 2018 | 1,142 |
| 9 | SEX‐HORMONE‐BINDING GLOBULIN | Clinical Endocrinology | 1974 | 1,080 |
| 10 | Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI) | Journal of Cardiovascular Magnetic Resonance | 2017 | 1,074 |
| 11 | Intrauterine Growth Retardation and Postnatal Growth Failure Associated with Deletion of the Insulin-Like Growth Factor I Gene | New England Journal of Medicine | 1996 | 1,002 |
| 12 | Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002) | Gut | 2010 | 1,000 |
| 13 | Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin | Nature | 1982 | 984 |
| 14 | Who should measure quality of life, the doctor or the patient? | British Journal of Cancer | 1988 | 847 |
| 15 | Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study | Lancet, The | 1999 | 814 |
| 16 | Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial | Lancet, The | 2016 | 791 |
| 17 | Prevalence and correlates of personality disorder in Great Britain | British Journal of Psychiatry | 2006 | 778 |
| 18 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation | Europace | 2018 | 767 |
| 19 | Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) | Lancet Oncology, The | 2009 | 738 |
| 20 | Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone) | Pain Practice | 2008 | 710 |
| 21 | Guidelines for Acromegaly Management: An Update | Journal of Clinical Endocrinology and Metabolism | 2009 | 701 |
| 22 | Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial | Lancet Oncology, The | 2014 | 695 |
| 23 | HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome | Nature Genetics | 2002 | 686 |
| 24 | Attitudes to chemotherapy: comparing views of patients with cancer with those of doctors, nurses, and general public. | BMJ: British Medical Journal | 1990 | 679 |
| 25 | Tumour necrosis factor alpha in stool as a marker of intestinal inflammation | Lancet, The | 1992 | 669 |
| 26 | 2019 ESC Guidelines for the management of patients with supraventricular tachycardiaThe Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC) | European Heart Journal | 2020 | 647 |
| 27 | European guidelines for quality assurance in breast cancer screening and diagnosis. Fourth edition—summary document | Annals of Oncology | 2008 | 620 |
| 28 | Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations | Thorax | 2000 | 616 |
| 29 | The Diagnosis and Differential Diagnosis of Cushing’s Syndrome and Pseudo-Cushing’s States | Endocrine Reviews | 1998 | 614 |
| 30 | THE INCIDENCE OF ALKAPTONURIA : A STUDY IN CHEMICAL INDIVIDUALITY. | Lancet, The | 1902 | 599 |
| 31 | Early Therapy Improves Outcomes of Exacerbations of Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2004 | 596 |
| 32 | European Society of Cardiology: Cardiovascular Disease Statistics 2017 | European Heart Journal | 2018 | 595 |
| 33 | Pheochromocytoma: recommendations for clinical practice from the First International Symposium | Nature Clinical Practice Endocrinology and Metabolism | 2007 | 581 |
| 34 | Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry | Biochemical Journal | 2003 | 580 |
| 35 | The Diagnosis and Medical Management of Advanced Neuroendocrine Tumors | Endocrine Reviews | 2004 | 562 |
| 36 | Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia | Cancer Cell | 2011 | 545 |
| 37 | Guidelines for the diagnosis and management of adult aplastic anaemia | British Journal of Haematology | 2016 | 539 |
| 38 | THE URETHRAL PRESSURE PROFILE | British Journal of Urology | 1969 | 523 |
| 39 | Revised FIGO staging for gynaecological cancer | BJOG: an International Journal of Obstetrics and Gynaecology | 1989 | 519 |
| 40 | Ghrelin?a hormone with multiple functions | Frontiers in Neuroendocrinology | 2004 | 496 |
| 41 | Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial | Blood | 2007 | 485 |
| 42 | LONG-TERM OUTCOME OF TREATING RHEUMATOID ARTHRITIS: RESULTS AFTER 20 YEARS | Lancet, The | 1987 | 483 |
| 43 | Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease. | Gut | 1993 | 482 |
| 44 | Brief, high-temperature heat denaturation (pressure cooking): A simple and effective method of antigen retrieval for routinely processed tissues | Journal of Pathology | 1994 | 451 |
| 45 | European Phase II Study of Rituximab (Chimeric Anti-CD20 Monoclonal Antibody) for Patients With Newly Diagnosed Mantle-Cell Lymphoma and Previously Treated Mantle-Cell Lymphoma, Immunocytoma, and Small B-Cell Lymphocytic Lymphoma | Journal of Clinical Oncology | 2000 | 448 |
| 46 | A trithorax–like gene is interrupted by chromosome 11q23 translocations in acute leukaemias | Nature Genetics | 1992 | 443 |
| 47 | Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease. | Gut | 1991 | 441 |
| 48 | Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine | Clinical and Experimental Immunology | 2008 | 427 |
| 49 | Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study | Lancet, The | 1992 | 423 |
| 50 | Elderly people's definitions of quality of life | Social Science and Medicine | 1995 | 423 |
