| # | Title | Journal | Year | Citations |
|---|
| 1 | STRING v10: protein–protein interaction networks, integrated over the tree of life | Nucleic Acids Research | 2015 | 9,029 |
| 2 | De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis | Nature Protocols | 2013 | 7,054 |
| 3 | Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 | Journal of the American College of Cardiology | 2020 | 4,468 |
| 4 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 5 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 6 | Europe-wide reduction in primary productivity caused by the heat and drought in 2003 | Nature | 2005 | 3,245 |
| 7 | The size and burden of mental disorders and other disorders of the brain in Europe 2010 | European Neuropsychopharmacology | 2011 | 2,930 |
| 8 | On the separation of net ecosystem exchange into assimilation and ecosystem respiration: review and improved algorithm | Global Change Biology | 2005 | 2,778 |
| 9 | Formal Concept Analysis | Global Change Biology | 1999 | 2,676 |
| 10 | Riboflavin/ultraviolet-a–induced collagen crosslinking for the treatment of keratoconus | American Journal of Ophthalmology | 2003 | 2,473 |
| 11 | Visual Genome: Connecting Language and Vision Using Crowdsourced Dense Image Annotations | International Journal of Computer Vision | 2017 | 2,422 |
| 12 | Glypican-1 identifies cancer exosomes and detects early pancreatic cancer | Nature | 2015 | 2,240 |
| 13 | KOH activation of carbon-based materials for energy storage | Journal of Materials Chemistry | 2012 | 2,127 |
| 14 | Control of Viremia in Simian Immunodeficiency Virus Infection by CD8+ Lymphocytes | Science | 1999 | 2,072 |
| 15 | Twelve‐month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States | International Journal of Methods in Psychiatric Research | 2012 | 2,042 |
| 16 | Construction of tight-binding-like potentials on the basis of density-functional theory: Application to carbon | Physical Review B | 1995 | 1,950 |
| 17 | Multilevel Voltage-Source-Converter Topologies for Industrial Medium-Voltage Drives | IEEE Transactions on Industrial Electronics | 2007 | 1,938 |
| 18 | Growth, innovation, scaling, and the pace of life in cities | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 1,917 |
| 19 | The ODD protocol: A review and first update | Ecological Modelling | 2010 | 1,913 |
| 20 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 21 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 22 | Wikidata | Communications of the ACM | 2014 | 1,770 |
| 23 | Flexible metal–organic frameworks | Chemical Society Reviews | 2014 | 1,741 |
| 24 | Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates | Cell | 2019 | 1,739 |
| 25 | Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients | Arthritis and Rheumatism | 2002 | 1,736 |
| 26 | The State and Fate of Himalayan Glaciers | Science | 2012 | 1,633 |
| 27 | Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial | Lancet, The | 2019 | 1,625 |
| 28 | Scenarios for 5G mobile and wireless communications: the vision of the METIS project | Lancet, The | 2014 | 1,616 |
| 29 | Tackling antibiotic resistance: the environmental framework | Nature Reviews Microbiology | 2015 | 1,612 |
| 30 | Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells | Nature Genetics | 2005 | 1,591 |
| 31 | Gap filling strategies for defensible annual sums of net ecosystem exchange | Agricultural and Forest Meteorology | 2001 | 1,579 |
| 32 | Gaia Data Release 2 | Astronomy and Astrophysics | 2018 | 1,576 |
| 33 | Iron Catalysis in Organic Synthesis | Chemical Reviews | 2015 | 1,500 |
| 34 | A Survey on Neutral-Point-Clamped Inverters | IEEE Transactions on Industrial Electronics | 2010 | 1,459 |
| 35 | Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma | Nature | 2007 | 1,446 |
| 36 | Highly Efficient Organic Devices Based on Electrically Doped Transport Layers | Chemical Reviews | 2007 | 1,443 |
| 37 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 38 | Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice | Science | 2001 | 1,414 |
| 39 | Multicellular tumor spheroids: An underestimated tool is catching up again | Journal of Biotechnology | 2010 | 1,376 |
| 40 | Brown adipose tissue activity controls triglyceride clearance | Nature Medicine | 2011 | 1,367 |
| 41 | Spheroid-based drug screen: considerations and practical approach | Nature Protocols | 2009 | 1,353 |
| 42 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 43 | Wetting and Self-Cleaning Properties of Artificial Superhydrophobic Surfaces | Langmuir | 2005 | 1,311 |
| 44 | Sex differences in HPA axis responses to stress: a review | Biological Psychology | 2005 | 1,264 |
| 45 | Isolation and Synthesis of Biologically Active Carbazole Alkaloids | Chemical Reviews | 2002 | 1,263 |
| 46 | Highly Conductive PEDOT:PSS Electrode with Optimized Solvent and Thermal Post‐Treatment for ITO‐Free Organic Solar Cells | Advanced Functional Materials | 2011 | 1,218 |
| 47 | Conduction at domain walls in oxide multiferroics | Nature Materials | 2009 | 1,212 |
| 48 | New advances in nanographene chemistry | Chemical Society Reviews | 2015 | 1,212 |
| 49 | Genome-wide association study identifies 30 loci associated with bipolar disorder | Nature Genetics | 2019 | 1,191 |
| 50 | The Future of Industrial Communication: Automation Networks in the Era of the Internet of Things and Industry 4.0 | IEEE Industrial Electronics Magazine | 2017 | 1,183 |
