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Top Articles

#TitleJournalYearCitations
1The ORCA program systemWiley Interdisciplinary Reviews: Computational Molecular Science20129,098
2Solutions for a cultivated planetNature20115,821
3Purity of the sacred lotus, or escape from contamination in biological surfacesPlanta19975,815
4Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
5Neuroinflammation in Alzheimer's diseaseLancet Neurology, The20154,129
6Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's diseaseNature Genetics20133,741
7Crop losses to pestsJournal of Agricultural Science20063,573
8A Mammalian microRNA Expression Atlas Based on Small RNA Library SequencingCell20073,390
9GPOWER: A general power analysis programBehavior Research Methods19963,223
10Review of Particle PhysicsProgress of Theoretical and Experimental Physics20203,177
11Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
12Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)Epilepsia20052,809
13Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's diseaseNature Genetics20092,697
14Alzheimer's diseaseLancet, The20162,430
15Activation and regulation of the inflammasomesNature Reviews Immunology20132,373
16Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 ExpressionJournal of Immunology20092,281
17The dynamic window approach to collision avoidanceIEEE Robotics and Automation Magazine19972,273
18Methodological nationalism and beyond: nation-state building, migration and the social sciencesGlobal Networks20022,270
19The bonn meson-exchange model for the nucleon—nucleon interactionPhysics Reports19872,228
20Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressionNature Genetics20182,224
21Climate Change Impacts on Global Food SecurityScience20132,131
22Revealing structure and assembly cues for Arabidopsis root-inhabiting bacterial microbiotaNature20122,127
23Phylogenomics resolves the timing and pattern of insect evolutionScience20142,096
245'-Triphosphate RNA Is the Ligand for RIG-IScience20062,094
25Drought and Salt Tolerance in PlantsCritical Reviews in Plant Sciences20052,081
26Indications of nonlinear deterministic and finite-dimensional structures in time series of brain electrical activity: Dependence on recording region and brain statePhysical Review E20012,068
27NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 miceNature20132,063
28Efficient, approximate and parallel Hartree–Fock and hybrid DFT calculations. A ‘chain-of-spheres’ algorithm for the Hartree–Fock exchangeChemical Physics20092,010
29A new antibiotic kills pathogens without detectable resistanceNature20151,991
30A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseasesNature Medicine20151,967
31Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processingNature Genetics20191,962
32DNA methylation-based classification of central nervous system tumoursNature20181,872
33Human3.6M: Large Scale Datasets and Predictive Methods for 3D Human Sensing in Natural EnvironmentsIEEE Transactions on Pattern Analysis and Machine Intelligence20141,869
34A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's diseaseAlzheimer's and Dementia20141,863
35A theory of reciprocityGames and Economic Behavior20061,839
36DBpedia – A large-scale, multilingual knowledge base extracted from WikipediaSemantic Web20151,826
37Defining the role of common variation in the genomic and biological architecture of adult human heightNature Genetics20141,818
38IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapyNature Genetics20091,808
39Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study GroupJournal of the American Medical Directors Association20131,767
40Genome-wide association study reveals genetic risk underlying Parkinson's diseaseNature Genetics20091,745
41Atopic DermatitisNew England Journal of Medicine20081,730
42Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's diseaseNature Genetics20111,708
43Temperature increase reduces global yields of major crops in four independent estimatesProceedings of the National Academy of Sciences of the United States of America20171,708
44GFN2-xTB—An Accurate and Broadly Parametrized Self-Consistent Tight-Binding Quantum Chemical Method with Multipole Electrostatics and Density-Dependent Dispersion ContributionsJournal of Chemical Theory and Computation20191,704
45Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclatureNatural Product Reports20131,692
46Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage ActivationImmunity20141,692
47Large-scale association analysis identifies 13 new susceptibility loci for coronary artery diseaseNature Genetics20111,685
48Review of Particle PhysicsProgress of Theoretical and Experimental Physics20221,679
49Common variants conferring risk of schizophreniaNature20091,572
50Electrochemical Properties of Polyoxometalates as ElectrocatalystsChemical Reviews19981,544