| Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice | Nature | 2005 | 591 |
| Risk of thyroid cancer after exposure to 131I in childhood | Journal of the National Cancer Institute | 2005 | 430 |
| Pd-catalyzed C3-selective allylation of indoles with allyl alcohols promoted by triethylborane | Journal of the American Chemical Society | 2005 | 323 |
| Negative regulation of Toll-like-receptor signaling by IRF-4 | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 311 |
| Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production | Brain Research | 2005 | 277 |
| Twelve-month prevalence, severity, and treatment of common mental disorders in communities in Japan: preliminary finding from the World Mental Health Japan Survey 2002-2003 | Psychiatry and Clinical Neurosciences | 2005 | 266 |
| Rapid detection and differentiation of dengue virus serotypes by a real-time reverse transcription-loop-mediated isothermal amplification assay | Journal of Clinical Microbiology | 2005 | 262 |
| Activation of Allyl Alcohols as Allyl Cations, Allyl Anions, and Amphiphilic Allylic Species by Palladium | European Journal of Organic Chemistry | 2005 | 241 |
| Acute physical stress elevates mouse period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive element | Journal of Biological Chemistry | 2005 | 211 |
| Structure-activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells | FEBS Letters | 2005 | 202 |
| Molecular determinants of topoisomerase I poisoning by lamellarins: comparison with camptothecin and structure-activity relationships | Journal of Medicinal Chemistry | 2005 | 187 |
| Human mesenchymal stem cells successfully improve skin-substitute wound healing | British Journal of Dermatology | 2005 | 177 |
| The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus | Journal of Virology | 2005 | 172 |
| A multi-mode-driven molecular shuttle: photochemically and thermally reactive azobenzene rotaxanes | Journal of the American Chemical Society | 2005 | 170 |
| Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis | Annals of Neurology | 2005 | 146 |
| Effect of dietary taurine levels on growth and feeding behavior of juvenile Japanese flounder Paralichthys olivaceus | Aquaculture | 2005 | 123 |
| Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells | American Journal of Physiology - Cell Physiology | 2005 | 122 |
| Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeys | Journal of General Virology | 2005 | 122 |
| Estrogen differentially regulates expression of Per1 and Per2 genes between central and peripheral clocks and between reproductive and nonreproductive tissues in female rats | Journal of Neuroscience Research | 2005 | 118 |
| Regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998-2002) | Diagnostic Microbiology and Infectious Disease | 2005 | 117 |
| Superoxide production by marine microalgae | Marine Biology | 2005 | 113 |
| Nuclear localization of Japanese encephalitis virus core protein enhances viral replication | Journal of Virology | 2005 | 113 |
| Molecular determinants for subcellular localization of hepatitis C virus core protein | Journal of Virology | 2005 | 111 |
| Identification of a 3.0-kb major recombination hotspot in patients with Sotos syndrome who carry a common 1.9-Mb microdeletion | American Journal of Human Genetics | 2005 | 110 |
| Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 108 |
