| # | Title | Journal | Year | Citations |
|---|
| 1 | Fiji: an open-source platform for biological-image analysis | Nature Methods | 2012 | 47,818 |
| 2 | The Hallmarks of Cancer | Cell | 2000 | 24,832 |
| 3 | ImageNet Large Scale Visual Recognition Challenge | International Journal of Computer Vision | 2015 | 24,215 |
| 4 | A Computational Approach to Edge Detection | IEEE Transactions on Pattern Analysis and Machine Intelligence | 1986 | 21,603 |
| 5 | THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS | Annals of the New York Academy of Sciences | 1949 | 20,417 |
| 6 | QUANTUM ESPRESSO: a modular and open-source software project for quantum simulations of materials | Journal of Physics Condensed Matter | 2009 | 18,183 |
| 7 | MicroRNAs: Target Recognition and Regulatory Functions | Cell | 2009 | 17,802 |
| 8 | Electronics and optoelectronics of two-dimensional transition metal dichalcogenides | Nature Nanotechnology | 2012 | 13,346 |
| 9 | Optical coherence tomography | Science | 1991 | 13,009 |
| 10 | Multiplex Genome Engineering Using CRISPR/Cas Systems | Science | 2013 | 12,725 |
| 11 | Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 | Nature Biotechnology | 2019 | 11,167 |
| 12 | Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets | Cell | 2005 | 10,880 |
| 13 | Cooperative Diversity in Wireless Networks: Efficient Protocols and Outage Behavior | IEEE Transactions on Information Theory | 2004 | 10,614 |
| 14 | An Integrative Theory of Prefrontal Cortex Function | Annual Review of Neuroscience | 2001 | 10,240 |
| 15 | An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest | NeuroImage | 2006 | 10,125 |
| 16 | How to share a secret | Communications of the ACM | 1979 | 10,025 |
| 17 | Integrins: Versatility, modulation, and signaling in cell adhesion | Cell | 1992 | 9,858 |
| 18 | Tissue engineering | Science | 1993 | 9,341 |
| 19 | Determining optical flow | Artificial Intelligence | 1981 | 9,134 |
| 20 | MicroRNA expression profiles classify human cancers | Nature | 2005 | 8,931 |
| 21 | Observation of Gravitational Waves from a Binary Black Hole Merger | Physical Review Letters | 2016 | 8,753 |
| 22 | Iterative minimization techniques forab initiototal-energy calculations: molecular dynamics and conjugate gradients | Reviews of Modern Physics | 1992 | 8,643 |
| 23 | Energy-efficient communication protocol for wireless microsensor networks | Reviews of Modern Physics | 0 | 8,440 |
| 24 | An application-specific protocol architecture for wireless microsensor networks | IEEE Transactions on Wireless Communications | 2002 | 8,330 |
| 25 | How Much Should We Trust Differences-In-Differences Estimates? | Quarterly Journal of Economics | 2004 | 7,850 |
| 26 | Integrins | Cell | 2002 | 7,714 |
| 27 | Nanocarriers as an emerging platform for cancer therapy | Nature Nanotechnology | 2007 | 7,469 |
| 28 | The Colonial Origins of Comparative Development: An Empirical Investigation | American Economic Review | 2001 | 7,321 |
| 29 | Most mammalian mRNAs are conserved targets of microRNAs | Genome Research | 2009 | 7,226 |
| 30 | Powering the planet: Chemical challenges in solar energy utilization | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 7,148 |
| 31 | Commentary: The Materials Project: A materials genome approach to accelerating materials innovation | APL Materials | 2013 | 6,913 |
| 32 | Low-density parity-check codes | IEEE Transactions on Information Theory | 1962 | 6,837 |
| 33 | Random effects structure for confirmatory hypothesis testing: Keep it maximal | Journal of Memory and Language | 2013 | 6,772 |
| 34 | The organization of the human cerebral cortex estimated by intrinsic functional connectivity | Journal of Neurophysiology | 2011 | 6,420 |
| 35 | GW170817: Observation of Gravitational Waves from a Binary Neutron Star Inspiral | Physical Review Letters | 2017 | 6,413 |
| 36 | Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Nature | 1993 | 6,331 |
| 37 | A Model of Leptons | Physical Review Letters | 1967 | 6,195 |
| 38 | Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex | Science | 2005 | 5,761 |
| 39 | Integrative analysis of 111 reference human epigenomes | Nature | 2015 | 5,653 |
| 40 | Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations | Quarterly Journal of Economics | 1993 | 5,598 |
| 41 | A robust layered control system for a mobile robot | IEEE Journal of Robotics and Automation | 1986 | 5,504 |
| 42 | Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals | Nature Genetics | 2003 | 5,434 |
| 43 | The Structure of Haplotype Blocks in the Human Genome | Science | 2002 | 5,300 |
| 44 | A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE | Journal of Biological Chemistry | 1952 | 5,298 |
| 45 | Convective Transport in Nanofluids | Journal of Heat Transfer | 2006 | 5,283 |
| 46 | Unconventional superconductivity in magic-angle graphene superlattices | Nature | 2018 | 5,221 |
| 47 | Large Area, Few-Layer Graphene Films on Arbitrary Substrates by Chemical Vapor Deposition | Nano Letters | 2009 | 5,220 |
| 48 | Resonance Absorption by Nuclear Magnetic Moments in a Solid | Physical Review | 1946 | 4,976 |
| 49 | Raman spectroscopy in graphene | Physics Reports | 2009 | 4,853 |
| 50 | Efficient Graph-Based Image Segmentation | International Journal of Computer Vision | 2004 | 4,789 |
