| # | Title | Journal | Year | Citations |
|---|
| 1 | Mesocorticolimbic dopaminergic network: functional and regulatory roles | Physiological Reviews | 1991 | 1,104 |
| 2 | Laser assisted bioprinting of engineered tissue with high cell density and microscale organization | Biomaterials | 2010 | 686 |
| 3 | High-Frequency Stimulation Produces a Transient Blockade of Voltage-Gated Currents in Subthalamic Neurons | Journal of Neurophysiology | 2001 | 483 |
| 4 | Pathophysiology of levodopa-induced dyskinesia: Potential for new therapies | Nature Reviews Neuroscience | 2001 | 472 |
| 5 | Distribution, biochemistry and function of striatal adenosine A2A receptors | Progress in Neurobiology | 1999 | 468 |
| 6 | Lipid Rafts in Higher Plant Cells | Journal of Biological Chemistry | 2004 | 428 |
| 7 | Collagen types analysis and differentiation by FTIR spectroscopy | Analytical and Bioanalytical Chemistry | 2009 | 406 |
| 8 | Epicardial Ventricular Tachycardia Ablation | Journal of the American College of Cardiology | 2010 | 375 |
| 9 | Predictors of Early Death Risk in Older Patients Treated With First-Line Chemotherapy for Cancer | Journal of Clinical Oncology | 2012 | 366 |
| 10 | Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies | International Journal of Geriatric Psychiatry | 2015 | 363 |
| 11 | Secular Trends in the Performance of Children and Adolescents (1980???2000) | Sports Medicine | 2003 | 355 |
| 12 | Long-term use of standardised ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial | Lancet Neurology, The | 2012 | 331 |
| 13 | The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling | Plant Molecular Biology | 2008 | 317 |
| 14 | Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project | Journal of Neurology, Neurosurgery and Psychiatry | 1999 | 310 |
| 15 | Phrenic Nerve Injury After Atrial Fibrillation Catheter Ablation | Journal of the American College of Cardiology | 2006 | 310 |
| 16 | Pathophysiology of obsessive–compulsive disorder | Progress in Neurobiology | 2004 | 303 |
| 17 | Outcome After Implantation of a Cardioverter-Defibrillator in Patients With Brugada Syndrome | Circulation | 2006 | 303 |
| 18 | Dental evidence for ontogenetic differences between modern humans and Neanderthals | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 299 |
| 19 | ESPEN Guidelines on Parenteral Nutrition: Adult Renal Failure | Clinical Nutrition | 2009 | 297 |
| 20 | Cats protecting birds: modelling the mesopredator release effect | Journal of Animal Ecology | 1999 | 284 |
| 21 | Fatigue, sleep restriction and driving performance | Accident Analysis and Prevention | 2005 | 280 |
| 22 | Novel pharmacological targets for the treatment of Parkinson's disease | Nature Reviews Drug Discovery | 2006 | 262 |
| 23 | Severe portal hypertensive gastropathy and antral vascular ectasia are distinct entities in patients with cirrhosis | Gastroenterology | 1995 | 238 |
| 24 | International multicentre pooled analysis of late postnatal mother-to-child transmission of HIV-1 infection | Lancet, The | 1998 | 238 |
| 25 | Algebraic languages and polyominoes enumeration | Theoretical Computer Science | 1984 | 230 |
| 26 | CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial | Lancet, The | 2006 | 230 |
| 27 | A Deductive Mapping Strategy for Atrial Tachycardia Following Atrial Fibrillation Ablation: Importance of Localized Reentry | Journal of Cardiovascular Electrophysiology | 2009 | 227 |
| 28 | Three Arabidopsis Fatty Acyl-Coenzyme A Reductases, FAR1, FAR4, and FAR5, Generate Primary Fatty Alcohols Associated with Suberin Deposition | Plant Physiology | 2010 | 227 |
| 29 | Evidence for nonsynaptic serotonergic and noradrenergic innervation of the rat dorsal horn and possible involvement of neuron-glia interactions | Neuroscience | 1993 | 226 |
| 30 | Under-reporting of adverse drug reactions | European Journal of Clinical Pharmacology | 1998 | 218 |
| 31 | Abolition and Reversal of Strain Differences in Behavioral Responses to Drugs of Abuse After a Brief Experience | Science | 2000 | 218 |
| 32 | Mutations in SCN10A Are Responsible for a Large Fraction of Cases of Brugada Syndrome | Journal of the American College of Cardiology | 2014 | 212 |
| 33 | Laser-assisted cell printing: principle, physical parameters versus cell fate and perspectives in tissue engineering | Nanomedicine | 2010 | 211 |
| 34 | Rabbits killing birds: modelling the hyperpredation process | Journal of Animal Ecology | 2000 | 204 |
| 35 | Effects of acute physical exercise on central serotonergic systems | Medicine and Science in Sports and Exercise | 1997 | 196 |
| 36 | 5-HT2A and 5-HT2C/2B Receptor Subtypes Modulate Dopamine Release Induced in Vivo by Amphetamine and Morphine in Both the Rat Nucleus Accumbens and Striatum | Neuropsychopharmacology | 2002 | 189 |
| 37 | Postnatal Stimulation of the Pups Counteracts Prenatal Stress-Induced Deficits in Hippocampal Neurogenesis | Biological Psychiatry | 2006 | 189 |
| 38 | Risk factors for failure of Helicobacter pylori therapy — results of an individual data analysis of 2751 patients | Alimentary Pharmacology and Therapeutics | 2003 | 181 |
| 39 | Development and implementation of standardized respiratory chain spectrophotometric assays for clinical diagnosis | Mitochondrion | 2009 | 178 |
| 40 | A simple method to measure stride length as an index of nigrostriatal dysfunction in mice | Journal of Neuroscience Methods | 2002 | 170 |
| 41 | What Aspects of Social Network Are Protective for Dementia? Not the Quantity But the Quality of Social Interactions Is Protective Up to 15 Years Later | Psychosomatic Medicine | 2010 | 166 |
| 42 | Oxythiamine and dehydroepiandrosterone induce a G1phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle | FEBS Letters | 1999 | 164 |
| 43 | Acute and chronic effects of exercise on tissue sensitivity to glucocorticoids | Journal of Applied Physiology | 2003 | 162 |
| 44 | GαolfLevels Are Regulated by Receptor Usage and Control Dopamine and Adenosine Action in the Striatum | Journal of Neuroscience | 2001 | 156 |
| 45 | Mycoplasma genitalium, a New Species from the Human Urogenital Tract | International Journal of Systematic Bacteriology | 1983 | 155 |
| 46 | Subcutaneous Ustekinumab Provides Clinical Benefit for Two-Thirds of Patients With Crohn’s Disease Refractory to Anti–Tumor Necrosis Factor Agents | Clinical Gastroenterology and Hepatology | 2016 | 155 |
| 47 | Four Instrumental Activities of Daily Living Score as a Predictor of One-year Incident Dementia | Age and Ageing | 1993 | 154 |
| 48 | Age, performance and sleep deprivation | Journal of Sleep Research | 2004 | 153 |
| 49 | A hierarchical model of domains of disablement in the elderly: a longitudinal approach | Disability and Rehabilitation | 2000 | 152 |
| 50 | Anxiety- and activity-related effects of diazepam and chlordiazepoxide in the rat light/dark and dark/light tests | Behavioural Brain Research | 1997 | 151 |
