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Top Articles

#TitleJournalYearCitations
1Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative UltracentrifugeClinical Chemistry197226,892
2Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesPflugers Archiv European Journal of Physiology198117,126
3The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR ExperimentsClinical Chemistry200912,487
4SWISS-MODEL and the Swiss-Pdb Viewer: An environment for comparative protein modelingElectrophoresis199710,267
5Interrater reliability: the kappa statisticBiochemia Medica20129,684
6Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifugeClinical Chemistry19729,549
7Enzymatic Determination of Total Serum CholesterolClinical Chemistry19747,692
8Probability-based protein identification by searching sequence databases using mass spectrometry dataElectrophoresis19997,555
9The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel FiltrationScandinavian Journal of Clinical and Laboratory Investigation19686,229
10Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicineClinical Chemistry19935,582
11Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gelsElectrophoresis19873,913
12The Ki-67 protein: From the known and the unknownJournal of Cellular Physiology20003,848
13Determination of Glucose in Blood Using Glucose Oxidase with an Alternative Oxygen AcceptorAnnals of Clinical Biochemistry19693,706
14Proposed minimum reporting standards for chemical analysisMetabolomics20073,589
15A simple method for clinical assay of superoxide dismutase.Clinical Chemistry19883,238
16Modified Reagents for Determination of Urea and AmmoniaClinical Chemistry19623,226
17Flavonoid antioxidants: chemistry, metabolism and structure-activity relationshipsJournal of Nutritional Biochemistry20023,093
18Fabrication of microfluidic systems in poly(dimethylsiloxane)Electrophoresis20003,078
19Reactive Oxygen Species in Inflammation and Tissue InjuryAntioxidants and Redox Signaling20143,036
20A Rapid, Simple Spectrophotometric Method for Simultaneous Detection of Nitrate and NitriteNitric Oxide - Biology and Chemistry20012,859
21Quantitative Determination of Serum Triglycerides by the Use of EnzymesClinical Chemistry19732,793
22Interrater reliability: the kappa statisticBiochemia Medica20122,760
23Macrophage plasticity, polarization, and function in health and diseaseJournal of Cellular Physiology20182,693
24Albumin standards and the measurement of serum albumin with bromcresol greenClinica Chimica Acta19712,561
25Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250Electrophoresis19882,534
26A new automated colorimetric method for measuring total oxidant statusClinical Biochemistry20052,530
27Understanding Bland Altman analysisBiochemia Medica20152,511
28Role of reactive oxygen species (ROS) in apoptosis inductionApoptosis: an International Journal on Programmed Cell Death20002,406
29The MicroRNA Spectrum in 12 Body FluidsClinical Chemistry20102,332
30Enzymatic determination of total serum cholesterolClinical Chemistry19742,224
31A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cationClinical Biochemistry20042,151
32Nanoparticle-based targeted drug deliveryExperimental and Molecular Pathology20092,149
33Difference gel electrophoresis. A single gel method for detecting changes in protein extractsElectrophoresis19972,104
34Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide.Clinical Chemistry19822,053
35Cellular response to oxidative stress: Signaling for suicide and survivalJournal of Cellular Physiology20022,053
36Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol.Clinical Chemistry19822,037
37Conditions controlling the proliferation of haemopoietic stem cells in vitroJournal of Cellular Physiology19772,034
38Amino acids: metabolism, functions, and nutritionAmino Acids20092,007
39Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic DiseasesAntioxidants and Redox Signaling20131,938
40Protein carbonyl groups as biomarkers of oxidative stressClinica Chimica Acta20031,888
41Aptamers: An Emerging Class of Molecules That Rival Antibodies in DiagnosticsClinical Chemistry19991,882
42Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicineClinical Chemistry19931,831
43Bone Morphogenetic ProteinsGrowth Factors20041,787
44Electroimmuno AssayScandinavian Journal of Clinical and Laboratory Investigation19721,767
45Oxidative stress: a concept in redox biology and medicineRedox Biology20151,747
46Adult mesenchymal stem cells for tissue engineering versus regenerative medicineJournal of Cellular Physiology20071,731
47A simple method for determination of serum catalase activity and revision of reference rangeClinica Chimica Acta19911,705
48Free Radicals: Properties, Sources, Targets, and Their Implication in Various DiseasesIndian Journal of Clinical Biochemistry20151,694
49Blue silver: A very sensitive colloidal Coomassie G-250 staining for proteome analysisElectrophoresis20041,686
50Mitochondria, oxidative stress and cell deathApoptosis: an International Journal on Programmed Cell Death20071,674
51The current state of two-dimensional electrophoresis with immobilized pH gradientsElectrophoresis20001,670
52An Overview of Autophagy: Morphology, Mechanism, and RegulationAntioxidants and Redox Signaling20141,669
53Hirnpotential�nderungen bei Willk�rbewegungen und passiven Bewegungen des Menschen: Bereitschaftspotential und reafferente PotentialePflugers Archiv European Journal of Physiology19651,667
54Antioxidant enzymes and human diseasesClinical Biochemistry19991,656
55Glutathione: Overview of its protective roles, measurement, and biosynthesisMolecular Aspects of Medicine20091,647
56Molecular, pharmacological and functional diversity of 5-HT receptorsPharmacology Biochemistry and Behavior20021,637
57Free radical-mediated oxidation of free amino acids and amino acid residues in proteinsAmino Acids20031,637
58Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine ValuesClinical Chemistry20071,587
59Automated comparative protein structure modeling with SWISS‐MODEL and Swiss‐PdbViewer: A historical perspectiveElectrophoresis20091,574
60Regulation of glutathione synthesisMolecular Aspects of Medicine20091,567
61Physiological concentrations of purines and pyrimidinesMolecular and Cellular Biochemistry19941,557
62Flavonoids--Chemistry, metabolism, cardioprotective effects, and dietary sourcesJournal of Nutritional Biochemistry19961,542
63Microfluidic devices fabricated in Poly(dimethylsiloxane) for biological studiesElectrophoresis20031,532
64Determination of hydroxyprolineClinica Chimica Acta19671,484
65Cholesterol determination in high-density lipoproteins separated by three different methods.Clinical Chemistry19771,483
66Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and DiseasesAntioxidants and Redox Signaling20111,470
67Redox Regulation of Cell SurvivalAntioxidants and Redox Signaling20081,464
68Lipid peroxidation and antioxidants as biomarkers of tissue damageClinical Chemistry19951,455
69The endothelial glycocalyx: composition, functions, and visualizationPflugers Archiv European Journal of Physiology20071,440
70Proline accumulation in plants: a reviewAmino Acids20081,435
71Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrixJournal of Cellular Physiology19901,429
72Recent advances in the relationship between obesity, inflammation, and insulin resistanceEuropean Cytokine Network20061,415
73Oxidative stress and the amyloid beta peptide in Alzheimer’s diseaseRedox Biology20181,411
74Immune checkpoint inhibitors: recent progress and potential biomarkersExperimental and Molecular Medicine20181,410
75Stability of curcumin in buffer solutions and characterization of its degradation productsJournal of Pharmaceutical and Biomedical Analysis19971,401
76Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysisClinical Chemistry and Laboratory Medicine20201,400
77Medicinal plants: Traditions of yesterday and drugs of tomorrowMolecular Aspects of Medicine20061,398
78Ion Suppression in Mass SpectrometryClinical Chemistry20031,396
79Biomarkers of Oxidative Damage in Human DiseaseClinical Chemistry20061,395
80Role of oxygen radicals in DNA damage and cancer incidenceMolecular and Cellular Biochemistry20041,387
81The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an updateApoptosis: an International Journal on Programmed Cell Death20031,384
82Redefining Oxidative StressAntioxidants and Redox Signaling20061,381
83Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustressRedox Biology20171,378
84Simplified method for silver staining of proteins in polyacrylamide gels and the mechanism of silver stainingElectrophoresis19851,377
85Transcriptional Regulation by Nrf2Antioxidants and Redox Signaling20181,356
86Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Cycle or a Double-Edged Sword?Antioxidants and Redox Signaling20071,339
87The Chi-square test of independenceBiochemia Medica20131,339
88Serum Creatinine as an Index of Renal Function: New Insights into Old ConceptsClinical Chemistry19921,333
89Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the ratPharmacology Biochemistry and Behavior19861,325
90Human serum albumin: From bench to bedsideMolecular Aspects of Medicine20121,320
91Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric methodClinica Chimica Acta19781,298
92Therapeutic peptides: Historical perspectives, current development trends, and future directionsBioorganic and Medicinal Chemistry20181,298
93Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysisClinica Chimica Acta20201,289
94Reactive Oxygen Species and Antioxidant Defense in Plants under Abiotic Stress: Revisiting the Crucial Role of a Universal Defense RegulatorAntioxidants20201,288
95Liver regenerationJournal of Cellular Physiology20071,284
96Two-dimensional electrophoresis. The current state of two-dimensional electrophoresis with immobilized pH gradientsElectrophoresis19881,282
97Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery diseaseEuropean Journal of Clinical Investigation20091,281
98Development of therapeutic antibodies for the treatment of diseasesJournal of Biomedical Science20201,277
99Human bone marrow colony growth in agar-gelJournal of Cellular Physiology19701,270
100The Electrophoretic α;1-Globulin Pattern of Serum in α;1-Antitrypsin DeficiencyScandinavian Journal of Clinical and Laboratory Investigation19631,260