| # | Title | Journal | Year | Citations |
|---|
| 1 | Design and validation of a histological scoring system for nonalcoholic fatty liver disease | Hepatology | 2005 | 8,518 |
| 2 | Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes | Hepatology | 2016 | 7,346 |
| 3 | Management of hepatocellular carcinoma: An update | Hepatology | 2011 | 7,111 |
| 4 | The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic | Nature Reviews Gastroenterology and Hepatology | 2014 | 5,773 |
| 5 | Management of hepatocellular carcinoma | Hepatology | 2005 | 5,426 |
| 6 | Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis | Gastroenterology | 2007 | 4,828 |
| 7 | Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus | Gut | 2013 | 4,813 |
| 8 | The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases | Hepatology | 2018 | 4,738 |
| 9 | Changes of Intestinal Functions in Liver Cirrhosis | Inflammatory Intestinal Diseases | 2016 | 4,709 |
| 10 | Functional Bowel Disorders | Gastroenterology | 2006 | 4,197 |
| 11 | A model to predict survival in patients with end-stage liver disease | Hepatology | 2001 | 4,112 |
| 12 | Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review | Gastroenterology | 2012 | 4,013 |
| 13 | Acute Abdomen: A Rare Case of Ruptured Hepatocellular Carcinoma | Case Reports in Gastroenterology | 2017 | 3,851 |
| 14 | Steatohepatitis: A tale of two “hits”? | Gastroenterology | 1998 | 3,644 |
| 15 | An algorithm for the grading of activity in chronic hepatitis C | Hepatology | 1996 | 3,593 |
| 16 | Global patterns and trends in colorectal cancer incidence and mortality | Gut | 2017 | 3,497 |
| 17 | Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention | Nature Reviews Gastroenterology and Hepatology | 2018 | 3,487 |
| 18 | A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C | Hepatology | 2003 | 3,455 |
| 19 | Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection | Hepatology | 2006 | 3,343 |
| 20 | Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis | Hepatology | 1981 | 3,336 |
| 21 | Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity | Hepatology | 2004 | 3,250 |
| 22 | Nonalcoholic Steatohepatitis: A Proposal for Grading and Staging The Histological Lesions | American Journal of Gastroenterology | 1999 | 3,233 |
| 23 | The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based Consensus | American Journal of Gastroenterology | 2006 | 3,207 |
| 24 | Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics | Nature Reviews Gastroenterology and Hepatology | 2017 | 3,192 |
| 25 | The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets | Digestive Diseases | 2014 | 3,128 |
| 26 | Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases | Hepatology | 2018 | 3,096 |
| 27 | Japanese classification of gastric carcinoma: 3rd English edition | Gastric Cancer | 2011 | 3,039 |
| 28 | Development of a Crohn's Disease Activity Index | Gastroenterology | 1976 | 3,013 |
| 29 | Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆ | Gastroenterology | 1999 | 3,005 |
| 30 | The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association | Hepatology | 2012 | 2,935 |
| 31 | AASLD guidelines for the treatment of hepatocellular carcinoma | Hepatology | 2018 | 2,932 |
| 32 | Biology of Incretins: GLP-1 and GIP | Gastroenterology | 2007 | 2,918 |
| 33 | Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium | Gastroenterology | 2011 | 2,835 |
| 34 | Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma | Gastroenterology | 2012 | 2,753 |
| 35 | Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology | Canadian Journal of Gastroenterology & Hepatology | 2005 | 2,711 |
| 36 | Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences | Gastroenterology | 2004 | 2,658 |
| 37 | Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival | Hepatology | 2003 | 2,646 |
| 38 | Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance | Hepatology | 2018 | 2,620 |
| 39 | Diagnosis, management, and treatment of hepatitis C: An update | Hepatology | 2009 | 2,610 |
| 40 | Systematic review: the epidemiology and natural history of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis in adults | Alimentary Pharmacology and Therapeutics | 2011 | 2,569 |
| 41 | The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study | Gastroenterology | 2005 | 2,544 |
| 42 | Endoscopic sphincterotomy complications and their management: an attempt at consensus | Gastrointestinal Endoscopy | 1991 | 2,535 |
| 43 | Chronic hepatitis B: Update 2009 | Hepatology | 2009 | 2,506 |
| 44 | MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer | Gastroenterology | 2007 | 2,499 |
| 45 | A global view of hepatocellular carcinoma: trends, risk, prevention and management | Nature Reviews Gastroenterology and Hepatology | 2019 | 2,482 |
| 46 | A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts | Hepatology | 2000 | 2,466 |
| 47 | Classification of chronic hepatitis: Diagnosis, grading and staging | Hepatology | 1994 | 2,456 |
| 48 | Etiology and management of fecal incontinence | Diseases of the Colon and Rectum | 1993 | 2,453 |
| 49 | The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD | Hepatology | 2007 | 2,448 |
| 50 | The risk of colorectal cancer in ulcerative colitis: a meta-analysis | Gut | 2001 | 2,433 |
| 51 | Chronic hepatitis B | Hepatology | 2007 | 2,422 |
| 52 | Mechanisms of Hepatic Fibrogenesis | Gastroenterology | 2008 | 2,381 |
| 53 | Stool Form Scale as a Useful Guide to Intestinal Transit Time | Scandinavian Journal of Gastroenterology | 1997 | 2,375 |
| 54 | The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications | Gut | 2006 | 2,362 |
| 55 | Short chain fatty acids in human large intestine, portal, hepatic and venous blood. | Gut | 1987 | 2,348 |
| 56 | Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas | Gastroenterology | 1994 | 2,329 |
| 57 | Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma | Hepatology | 2002 | 2,322 |
| 58 | Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome | Gastroenterology | 2012 | 2,287 |
| 59 | Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome | Hepatology | 2003 | 2,276 |
| 60 | Management ofHelicobacter pyloriinfection—the Maastricht V/Florence Consensus Report | Gut | 2017 | 2,245 |
| 61 | Evidence for Gastrointestinal Infection of SARS-CoV-2 | Gastroenterology | 2020 | 2,222 |
| 62 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C | Gastroenterology | 2005 | 2,216 |
| 63 | Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism | Gut Microbes | 2016 | 2,214 |
| 64 | Model for end-stage liver disease (MELD) and allocation of donor livers | Gastroenterology | 2003 | 2,212 |
| 65 | Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis | Gastroenterology | 2013 | 2,211 |
| 66 | Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease | Gastroenterology | 2015 | 2,200 |
| 67 | Primary liver cancer: Worldwide incidence and trends | Gastroenterology | 2004 | 2,193 |
| 68 | Intraobserver and Interobserver Variations in Liver Biopsy Interpretation in Patients with Chronic Hepatitis C | Hepatology | 1994 | 2,184 |
| 69 | Japanese Classification of Gastric Carcinoma – 2nd English Edition – | Gastric Cancer | 1998 | 2,184 |
| 70 | Hepatocellular carcinoma in cirrhosis: Incidence and risk factors | Gastroenterology | 2004 | 2,168 |
| 71 | Colonic Health: Fermentation and Short Chain Fatty Acids | Journal of Clinical Gastroenterology | 2006 | 2,159 |
| 72 | European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease | Journal of Pediatric Gastroenterology and Nutrition | 2012 | 2,124 |
| 73 | Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence | Hepatology | 2013 | 2,118 |
| 74 | Nonalcoholic fatty liver disease: From steatosis to cirrhosis | Hepatology | 2006 | 2,116 |
| 75 | A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice | Gastroenterology | 1990 | 2,091 |
| 76 | Japanese gastric cancer treatment guidelines 2010 (ver. 3) | Gastric Cancer | 2011 | 2,086 |
| 77 | Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability | Gut | 2009 | 2,061 |
| 78 | Review article: the role of butyrate on colonic function | Alimentary Pharmacology and Therapeutics | 2008 | 2,048 |
| 79 | International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas | Pancreatology | 2012 | 2,043 |
| 80 | Long-term follow-up of patients with NAFLD and elevated liver enzymes | Hepatology | 2006 | 2,038 |
| 81 | Management ofHelicobacter pyloriinfection—the Maastricht IV/ Florence Consensus Report | Gut | 2012 | 2,023 |
| 82 | Japanese gastric cancer treatment guidelines 2014 (ver. 4) | Gastric Cancer | 2017 | 2,020 |
| 83 | Colorectal cancer screening and surveillance: Clinical guidelines and rationale?Update based on new evidence | Gastroenterology | 2003 | 2,016 |
| 84 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology | Gastroenterology | 2008 | 2,002 |
| 85 | U. S. Householder survey of functional gastrointestinal disorders | Digestive Diseases and Sciences | 1993 | 1,995 |
| 86 | Adalimumab for Maintenance of Clinical Response and Remission in Patients With Crohn’s Disease: The CHARM Trial | Gastroenterology | 2007 | 1,986 |
| 87 | Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis | Gastroenterology | 2017 | 1,983 |
| 88 | Early indicators of prognosis in fulminant hepatic failure | Gastroenterology | 1989 | 1,981 |
| 89 | Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification | Gut | 1999 | 1,959 |
| 90 | Inflammatory bowel disease: Etiology and pathogenesis | Gastroenterology | 1998 | 1,955 |
| 91 | Liver transplantation for hepatocellular carcinoma: Expansion of the tumor size limits does not adversely impact survival | Hepatology | 2001 | 1,931 |
| 92 | Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach | Gut | 2006 | 1,931 |
| 93 | Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability | Gastroenterology | 1989 | 1,916 |
| 94 | Bowel Disorders | Gastroenterology | 2016 | 1,912 |
| 95 | Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota | Gastroenterology | 1997 | 1,898 |
| 96 | The Functional Gastrointestinal Disorders and the Rome III Process | Gastroenterology | 2006 | 1,891 |
| 97 | Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection | American Journal of Gastroenterology | 2002 | 1,878 |
| 98 | Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: Resection versus transplantation | Hepatology | 1999 | 1,869 |
| 99 | Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis | Hepatology | 2010 | 1,857 |
| 100 | Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study | Gastroenterology | 2011 | 1,856 |
