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Top Articles

#TitleJournalYearCitations
1Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature1970254,572
2Basic local alignment search toolJournal of Molecular Biology199084,210
3Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Genome Biology201464,243
4Helical microtubules of graphitic carbonNature199139,609
5Detection of specific sequences among DNA fragments separated by gel electrophoresisJournal of Molecular Biology197535,579
6Collective dynamics of ‘small-world’ networksNature199834,950
7[20] Processing of X-ray diffraction data collected in oscillation modeMethods in Enzymology199730,489
8Electrochemical Photolysis of Water at a Semiconductor ElectrodeNature197229,718
9A low-cost, high-efficiency solar cell based on dye-sensitized colloidal TiO2 filmsNature199126,932
10clusterProfiler: an R Package for Comparing Biological Themes Among Gene ClustersOMICS A Journal of Integrative Biology201223,430
11Biodiversity hotspots for conservation prioritiesNature200022,944
12The central role of the propensity score in observational studies for causal effectsBiometrika198322,432
13A simple method for displaying the hydropathic character of a proteinJournal of Molecular Biology198222,379
14Highly accurate protein structure prediction with AlphaFoldNature202122,334
15MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model SpaceSystematic Biology201221,601
16Initial sequencing and analysis of the human genomeNature200121,405
17Learning representations by back-propagating errorsNature198620,251
18[13] Catalase in vitroMethods in Enzymology198419,785
19Two-dimensional gas of massless Dirac fermions in grapheneNature200519,319
20Antioxidant activity applying an improved ABTS radical cation decolorization assayFree Radical Biology and Medicine199918,632
21Issues and challenges facing rechargeable lithium batteriesNature200118,175
22A pneumonia outbreak associated with a new coronavirus of probable bat originNature202017,687
23Human-level control through deep reinforcement learningNature201517,308
24Building better batteriesNature200817,034
25Continuous cultures of fused cells secreting antibody of predefined specificityNature197516,812
26Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genesGenome Biology200216,773
27An integrated encyclopedia of DNA elements in the human genomeNature201216,093
28The value of the world's ecosystem services and natural capitalNature199715,878
29New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0Systematic Biology201015,775
30Double-slit photoelectron interference in strong-field ionization of the neon dimerNature Communications201915,641
31A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum LikelihoodSystematic Biology200315,623
32Ordered mesoporous molecular sieves synthesized by a liquid-crystal template mechanismNature199215,573
33Longitudinal data analysis using generalized linear modelsBiometrika198615,472
34[57] Sequencing end-labeled DNA with base-specific chemical cleavagesMethods in Enzymology198015,338
35A global reference for human genetic variationNature201514,863
36C60: BuckminsterfullereneNature198514,852
37The genetical evolution of social behaviour. IJournal of Theoretical Biology196414,566
38Model-based Analysis of ChIP-Seq (MACS)Genome Biology200814,393
39An analysis of variance test for normality (complete samples)Biometrika196514,384
40Differential expression analysis for sequence count dataGenome Biology201014,141
41Molecular portraits of human breast tumoursNature200013,655
42U1 snRNP regulates cancer cell migration and invasion in vitroNature Communications202013,413
43Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansNature199813,355
44Dendritic cells and the control of immunityNature199813,193
45Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology197713,094
46Structural absorption by barbule microstructures of super black bird of paradise feathersNature Communications201812,905
47Testing for a unit root in time series regressionBiometrika198812,870
48Positional cloning of the mouse obese gene and its human homologueNature199412,326
49Experimental observation of the quantum Hall effect and Berry's phase in grapheneNature200512,325
50[14] Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagentMethods in Enzymology199912,141
51Resilience and Stability of Ecological SystemsAnnual Review of Ecology, Evolution, and Systematics197312,111
52Comparative Protein Modelling by Satisfaction of Spatial RestraintsJournal of Molecular Biology199312,085
53Photoelectrochemical cellsNature200112,077
54Array programming with NumPyNature202012,073
55TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusionsGenome Biology201312,012
56Graphene-based composite materialsNature200611,838
57Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. CohenJournal of Molecular Biology200111,677
58A procedure for the isolation of deoxyribonucleic acid from micro-organismsJournal of Molecular Biology196111,549
59Basic Local Alignment Search ToolJournal of Molecular Biology199011,522
60Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic AcidNature195311,441
61Monte Carlo sampling methods using Markov chains and their applicationsBiometrika197011,436
62The plant immune systemNature200611,343
63The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineNature198011,157
64Learning the parts of objects by non-negative matrix factorizationNature199911,071
65Light-emitting diodes based on conjugated polymersNature199011,066
66In situ click chemistry generation of cyclooxygenase-2 inhibitorsNature Communications201711,016
67Studies on transformation of Escherichia coli with plasmidsJournal of Molecular Biology198310,933
68A synaptic model of memory: long-term potentiation in the hippocampusNature199310,840
69Surface plasmon subwavelength opticsNature200310,726
70A novel potent vasoconstrictor peptide produced by vascular endothelial cellsNature198810,683
71Comprehensive molecular portraits of human breast tumoursNature201210,601
72An obesity-associated gut microbiome with increased capacity for energy harvestNature200610,430
73Stages of embryonic development of the zebrafishDevelopmental Dynamics199510,376
74Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factorNature198710,308
75Mastering the game of Go with deep neural networks and tree searchNature201610,303
76The pathogenesis of atherosclerosis: a perspective for the 1990sNature199310,228
77[30] Microsomal lipid peroxidationMethods in Enzymology197810,154
78Structure, function and diversity of the healthy human microbiomeNature20129,995
79The functions of animal microRNAsNature20049,989
80A new coronavirus associated with human respiratory disease in ChinaNature20209,839
81A general method applicable to the search for similarities in the amino acid sequence of two proteinsJournal of Molecular Biology19709,781
82Large-scale pattern growth of graphene films for stretchable transparent electrodesNature20099,755
83Measurement of DiversityNature19499,704
84The missing memristor foundNature20089,683
85A human gut microbial gene catalogue established by metagenomic sequencingNature20109,658
86Cancer-related inflammationNature20089,652
87Mutations of the BRAF gene in human cancerNature20029,550
88Antioxidant Determinations by the Use of a Stable Free RadicalNature19589,444
89[34] Chlorophylls and carotenoids: Pigments of photosynthetic biomembranesMethods in Enzymology19879,375
90Analysis of protein-coding genetic variation in 60,706 humansNature20169,271
91Opportunities and challenges for a sustainable energy futureNature20129,089
92Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingNature20009,069
93A safe operating space for humanityNature20099,057
94Sequence and organization of the human mitochondrial genomeNature19819,054
95Functional rafts in cell membranesNature19979,038
96MicroRNA expression profiles classify human cancersNature20059,031
97Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsNature20078,982
98Metascape provides a biologist-oriented resource for the analysis of systems-level datasetsNature Communications20198,958
99In vitro selection of RNA molecules that bind specific ligandsNature19908,835
100A globally coherent fingerprint of climate change impacts across natural systemsNature20038,830